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    Process for the gelatin coating of medicaments
    1.
    发明授权
    Process for the gelatin coating of medicaments 有权
    药物明胶包衣的方法

    公开(公告)号：US6126987A

    公开(公告)日：2000-10-03

    申请号：US274761

    申请日：1999-03-23

    Applicant: Jeffrey D. Brehaut ,  Linn C. Hoover ,  Thomas Kucharski ,  Thomas C. Reiter ,  David J. Revelle ,  Daniel A. Slater ,  Luis R. Torres ,  Patrick Vo

    Inventor： Jeffrey D. Brehaut ,  Linn C. Hoover ,  Thomas Kucharski ,  Thomas C. Reiter ,  David J. Revelle ,  Daniel A. Slater ,  Luis R. Torres ,  Patrick Vo

    IPC: A61J3/06 ,  A23G3/24 ,  A23G7/00 ,  A61J3/00 ,  B05B15/12 ,  B05C3/10 ,  B65D1/36 ,  A61J3/07 ,  B05C3/09

    CPC classification number: A23G7/0025 ,  A23G3/24 ,  A61J3/005 ,  B65D1/36 ,  B05B15/1207 ,  B05C3/10 ,  Y10S53/90

    Abstract: A process and apparatus for the gelatin coating of medicaments which includes a continuous conveyer system to advance a plurality of pallets through a loading station, at least one dipping station, at least one dryer station, a reorientation station and an unloading station. Medicaments to be coated are loaded into pallets at the loading station and advanced to the first dipping station where a vacuum is applied to secure the medicament to the pallet. The pallet is inverted and a first portion of each of the medicaments is dipped into a coating mixture. The pallet is then returned to its upright position, the vacuum is removed and the coating is dried. The medicaments are then transferred from the first pallet to a second pallet by a reorientation mechanism. The second pallet is then advanced to a second dipping station which operates in the same manner as the first dipping station. The second pallet is advanced through the dryer station and the fully coated medicaments are ejected from the pallet into a container. The pallets used to hold the medicaments include a plate-like support member, on which rests a flexible mat having a rectangular array of receptacles including compliant diaphragm portions such that when a vacuum is applied to the pallet, the medicaments are secured thereto. The drying means includes air directing plates having sinusoidal rows of air directing apertures under which the medicaments to be dried are passed.

    Abstract translation: 用于药物明胶涂层的方法和装置，其包括连续输送系统，以通过装载站，至少一个浸渍站，至少一个干燥站，重新定向站和卸载站推进多个托盘。 待涂覆的药物装载在装载站的托盘中并且前进到第一浸渍站，在那里施加真空以将药剂固定到托盘上。 托盘倒置，每个药物的第一部分浸入涂料混合物中。 然后将托盘返回到其直立位置，除去真空并将涂层干燥。 然后通过重新定向机构将药物从第一托盘转移到第二托盘。 然后将第二托盘推进到以与第一浸渍站相同的方式操作的第二浸渍站。 第二个托盘通过干燥站前进，完全涂覆的药物从托盘中排出到容器中。 用于保持药物的托盘包括板状支撑构件，其上放置有具有矩形阵列的容器的柔性垫，其包括顺应性膜部分，使得当将真空施加到托盘时，药物被固定到其上。 干燥装置包括具有正弦排的空气引导孔的空气引导板，待干燥的药物在该空气引导孔下通过。

    Apparatus for holding solid compact medicaments during processing
    2.
    发明授权
    Apparatus for holding solid compact medicaments during processing 失效
    用于在加工过程中保持固体紧凑型药物的装置

    公开(公告)号：US5387287A

    公开(公告)日：1995-02-07

    申请号：US88501

    申请日：1993-07-07

    Applicant: Thomas C. Reiter ,  Peter A. Pastecki ,  Charles W. Pierson

    Inventor： Thomas C. Reiter ,  Peter A. Pastecki ,  Charles W. Pierson

    IPC: A23G3/24 ,  A61J3/00 ,  B05C3/09 ,  B05C13/00 ,  A61K9/00 ,  B23Q3/00 ,  B25B1/20

    CPC classification number: A61J3/005 ,  A23G3/24 ,  B05C13/00 ,  B05C3/09

    Abstract: An apparatus for holding a solid compact medicament has relatively displaceable, substantially planar first and second members having opposed edge portions. Each edge portion has at least one notch having an interior wall. Housing is provided for holding members in a substantially co-planar relationship. When members are displaced, preferably along a fixed axis, to a first position, the interior walls of the opposed, aligned notches define an open gripping jaw for receiving and subsequently releasing the caplet. Further, when members are displaced to a second position, the open gripping jaw then partially closes, thereby capturing the caplet securely within the notches in the gripping jaw for processing.

    Abstract translation: 用于保持固体紧凑型药物的装置具有相对位移的基本上平面的具有相对边缘部分的第一和第二构件。 每个边缘部分具有至少一个具有内壁的凹口。 为保持构件提供基本上共平面关系的壳体。 当构件优选地沿着固定的轴线移动到第一位置时，相对的对齐的凹口的内壁限定用于接收和随后释放盖子的敞开的夹持爪。 此外，当构件被移动到第二位置时，打开的夹爪然后部分地关闭，从而将封盖片牢固地捕获在夹爪中的凹口内用于处理。

    Apparatus for the gelatin coating of medicaments
    3.
    发明授权
    Apparatus for the gelatin coating of medicaments 失效
    用于药物明胶涂层的装置

    公开(公告)号：US5942034A

    公开(公告)日：1999-08-24

    申请号：US900225

    申请日：1997-07-24

    Applicant: Jeffrey D. Brehant ,  Linn C. Hoover ,  Thomas Kucharski ,  Thomas C. Reiter ,  David J. Revelle ,  Daniel A. Slater ,  Luis R. Torres ,  Patrick Vo

    Inventor： Jeffrey D. Brehant ,  Linn C. Hoover ,  Thomas Kucharski ,  Thomas C. Reiter ,  David J. Revelle ,  Daniel A. Slater ,  Luis R. Torres ,  Patrick Vo

    IPC: A61J3/06 ,  A23G3/24 ,  A23G7/00 ,  A61J3/00 ,  B05B15/12 ,  B05C3/10 ,  B65D1/36 ,  A23G3/00

    CPC classification number: A23G7/0025 ,  A23G3/24 ,  A61J3/005 ,  B65D1/36 ,  B05B15/1207 ,  B05C3/10 ,  Y10S53/90

    Abstract: A process and apparatus for the gelatin coating of medicaments which includes a continuous conveyer system to advance a plurality of pallets through a loading station, at least one dipping station, at least one dryer station, a reorientation station and an unloading station. Medicaments to be coated are loaded into pallets at the loading station and advanced to the first dipping station where a vacuum is applied to secure the medicament to the pallet. The pallet is inverted and a first portion of each of the medicaments is dipped into a coating mixture. The pallet is then returned to its upright position, the vacuum is removed and the coating is dried. The medicaments are then transferred from the first pallet to a second pallet by a reorientation mechanism. The second pallet is then advanced to a second dipping station which operates in the same manner as the first dipping station. The second pallet is advanced through the dryer station and the fully coated medicaments are ejected from the pallet into a container. The pallets used to hold the medicaments include a plate-like support member, on which rests a flexible mat having a rectangular array of receptacles including compliant diaphragm portions such that when a vacuum is applied to the pallet, the medicaments are secured thereto. The drying means includes air directing plates having sinusoidal rows of air directing apertures under which the medicaments to be dried are passed.

    Abstract translation: 用于药物明胶涂层的方法和装置，其包括连续输送系统，以通过装载站，至少一个浸渍站，至少一个干燥站，重新定向站和卸载站推进多个托盘。 待涂覆的药物装载在装载站的托盘中并且前进到第一浸渍站，在那里施加真空以将药剂固定到托盘上。 托盘倒置，每个药物的第一部分浸入涂料混合物中。 然后将托盘返回到其直立位置，除去真空并将涂层干燥。 然后通过重新定向机构将药物从第一托盘转移到第二托盘。 然后将第二托盘推进到以与第一浸渍站相同的方式操作的第二浸渍站。 第二个托盘通过干燥站前进，完全涂覆的药物从托盘中排出到容器中。 用于保持药物的托盘包括板状支撑构件，其上放置有具有矩形阵列的容器的柔性垫，其包括顺应性膜部分，使得当将真空施加到托盘时，药物被固定到其上。 干燥装置包括具有正弦排的空气引导孔的空气引导板，待干燥的药物在该空气引导孔下通过。

    Process and apparatus for holding medicaments to be coated
    5.
    发明授权
    Process and apparatus for holding medicaments to be coated 有权
    用于保持待涂药剂的方法和装置

    公开(公告)号：US06258400B1

    公开(公告)日：2001-07-10

    申请号：US09274759

    申请日：1999-03-23

    Applicant: Jeffrey D. Brehant ,  Linn C. Hoover ,  Thomas Kucharski ,  Thomas C. Reiter ,  David J. Revelle ,  Daniel A. Slater ,  Luis R. Torres ,  Patrick Vo

    Inventor： Jeffrey D. Brehant ,  Linn C. Hoover ,  Thomas Kucharski ,  Thomas C. Reiter ,  David J. Revelle ,  Daniel A. Slater ,  Luis R. Torres ,  Patrick Vo

    IPC: A61J103

    CPC classification number: A23G7/0025 ,  A23G3/24 ,  A61J3/005 ,  B05B16/20 ,  B05C3/10 ,  B65D1/36 ,  Y10S53/90

    Abstract: A process and apparatus for holding a plurality of medicaments to be coated is disclosed. A support member is provided having a receiving surface with a plurality of channels to communicate a vacuum across the receiving surface and an aperture operable to couple the plurality of channels to a vacuum source. A flexible mat having a perimeter shaped to engage the support member in a sealed relation is provided on the support member. The flexible mat includes a plurality of medicament receptacles mounted to a first surface and adapted to receive the medicaments. The medicament receptacles initially are in a first position when no vacuum is applied. In the first position, the medicament receptacles are positioned to receive a medicament. When a vacuum is applied, the medicament receptacles change to a second position in which the medicament receptacles are positioned to hold the medicament and permit coating thereof.

    Abstract translation: 公开了一种用于保持待涂覆的多种药物的方法和装置。 提供了一种支撑构件，其具有接收表面，该接收表面具有多个通道以在接收表面上传递真空，以及可操作以将多个通道耦合到真空源的孔。 在支撑构件上设置有具有成形为以密封关系与支撑构件接合的周边的柔性垫。 柔性垫包括安装到第一表面并适于接收药物的多个药物容器。 当不施加真空时，药物容器最初处于第一位置。 在第一位置，药物容器被定位成容纳药物。 当施加真空时，药物容器改变到第二位置，在该第二位置，药物容器被定位成保持药物并允许其涂覆。

    Curtain coating method and apparatus using dual wire edge guides
    7.
    发明授权
    Curtain coating method and apparatus using dual wire edge guides 失效
    帘线涂布方法和使用双线边缘导轨的设备

    公开(公告)号：US5328726A

    公开(公告)日：1994-07-12

    申请号：US979504

    申请日：1992-11-19

    Applicant: Thomas C. Reiter

    Inventor： Thomas C. Reiter

    IPC: B05C5/00 ,  B05C9/06 ,  B05D1/30 ,  G03C1/74

    CPC classification number: G03C1/74 ,  B05C5/008 ,  B05C9/06 ,  Y10S118/04

    Abstract: The present invention discloses edge guides (12) for use in guiding a curtain (17) of coating liquid onto a moving support. Each edge guide (12) is made of two or more small diameter wires (20) spaced apart a distance and running from the hopper lip (16) to the support web. The distance between the wires is approximately the thickness of the curtain. Flushing solution is introduced between the wires (20) near the hopper lip (16) and removed near the support web (15).

    Abstract translation: 本发明公开了一种用于将涂覆液体的帘幕（17）引导到移动的支撑件上的边缘引导件（12）。 每个边缘引导件（12）由两个或更多个间距距离的小直径的线（20）制成，并且从漏斗唇缘（16）延伸到支撑腹板。 电线之间的距离约为帘幕的厚度。 冲洗溶液引入靠近料斗唇缘（16）的线（20）之间，并在支撑腹板（15）附近被移除。

    Curtain coating method and apparatus
    8.
    发明授权
    Curtain coating method and apparatus 失效
    窗帘涂布方法及装置

    公开(公告)号：US4830887A

    公开(公告)日：1989-05-16

    申请号：US185207

    申请日：1988-04-22

    Applicant: Thomas C. Reiter

    Inventor： Thomas C. Reiter

    IPC: B05C5/00 ,  B05C9/06 ,  B05D1/30 ,  G03C1/74

    CPC classification number: G03C1/74 ,  B05C5/008 ,  B05D1/305 ,  B05C9/06 ,  G03C2001/7433 ,  G03C2001/7455 ,  G03C2001/747 ,  Y10S118/04

    Abstract: Method and apparatus for applying one or a plurality of superimposed layers of a photographic coating composition by the curtain coating method onto a moving support. The spacing between the edge guides, used to maintain the width of a curtain throughout its free fall from the coating hopper to the impingement line on the support, is arranged to coat less than the width of the support so as to provide an uncoated margin on the support. The curtain fluids are extracted from the edge region of the falling curtain by connecting a suction device to the edge guides near the point of impingement of the falling curtain, thus substantially reducing the thickness of the curtain at its edge region and thereby reducing the thickness of the coated edges.

    Abstract translation: 通过帘式涂布方法将一个或多个照相涂料组合物叠加层施加到移动载体上的方法和装置。 边缘引导件之间的间距用于将窗帘的宽度保持在从涂覆料斗自由落下到支撑件上的冲击线上，布置成小于支撑件的宽度以便提供未涂覆的边缘 支撑。 通过将抽吸装置连接到落下的帷幕撞击点附近的边缘导向器，帘幕流体从帷幕的边缘区域被抽出，从而大大减小了窗帘边缘区域的厚度，从而减小了帘幕的厚度 涂层边缘。

    Process and apparatus for drying a plurality of dip-coated medicaments
    9.
    发明授权
    Process and apparatus for drying a plurality of dip-coated medicaments 有权
    用于干燥多种浸涂药物的方法和设备

    公开(公告)号：US06195911B1

    公开(公告)日：2001-03-06

    申请号：US09274760

    申请日：1999-03-23

    Applicant: Jeffrey D. Brehant ,  Linn C. Hoover ,  Thomas Kucharski ,  Thomas C. Reiter ,  David J. Revelle ,  Daniel A. Slater ,  Luis R. Torres ,  Patrick Vo

    Inventor： Jeffrey D. Brehant ,  Linn C. Hoover ,  Thomas Kucharski ,  Thomas C. Reiter ,  David J. Revelle ,  Daniel A. Slater ,  Luis R. Torres ,  Patrick Vo

    IPC: F26B300

    CPC classification number: A23G7/0025 ,  A23G3/24 ,  A61J3/005 ,  B05B16/20 ,  B05C3/10 ,  B65D1/36 ,  Y10S53/90

    Abstract: A process and apparatus for the gelatin coating of medicaments which includes a continuous conveyer system to advance a plurality of pallets through a loading station, at least one dipping station, at least one dryer station, a reorientation station and an unloading station. Medicaments to be coated are loaded into pallets at the loading station and advanced to the first dipping station where a vacuum is applied to secure the medicament to the pallet. The pallet is inverted and a first portion of each of the medicaments is dipped into a coating mixture. The pallet is then returned to its upright position, the vacuum is removed and the coating is dried. The medicaments are then transferred from the first pallet to a second pallet by a reorientation mechanism. The second pallet is then advanced to a second dipping station which operates in the same manner as the first dipping station. The second pallet is advanced through the dryer station and the fully coated medicaments are ejected from the pallet into a container. The pallets used to hold the medicaments include a plate-like support member, on which rests a flexible mat having a rectangular array of receptacles including compliant diaphragm portions such that when a vacuum is applied to the pallet, the medicaments are secured thereto. The drying means includes air directing plates having sinusoidal rows of air directing apertures under which the medicaments to be dried are passed.

    Abstract translation: 用于药物明胶涂层的方法和装置，其包括连续输送系统，以通过装载站，至少一个浸渍站，至少一个干燥站，重新定向站和卸载站推进多个托盘。 待涂覆的药物装载在装载站的托盘中并且前进到第一浸渍站，在那里施加真空以将药剂固定到托盘上。 托盘倒置，每个药物的第一部分浸入涂料混合物中。 然后将托盘返回到其直立位置，除去真空并将涂层干燥。 然后通过重新定向机构将药物从第一托盘转移到第二托盘。 然后将第二托盘推进到以与第一浸渍站相同的方式操作的第二浸渍站。 第二个托盘通过干燥站前进，完全涂覆的药物从托盘中排出到容器中。 用于保持药物的托盘包括板状支撑构件，其上放置有具有矩形阵列的容器的柔性垫，其包括顺应性膜部分，使得当将真空施加到托盘时，药物被固定到其上。 干燥装置包括具有正弦排的空气引导孔的空气引导板，待干燥的药物在该空气引导孔下通过。

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