OPTICAL CAVITY ENHANCEMENT FOR MULTI-PHOTON MICROSCOPY

    公开(公告)号:US20240044797A1

    公开(公告)日:2024-02-08

    申请号:US18228989

    申请日:2023-08-01

    Applicant: Thorlabs, Inc.

    Abstract: A system and method of producing energetic laser pulses suitable for multi-photon microscopy, in which laser pulses from an ultrafast pump source operating at greater than 40 MHz repetition rate are directed onto an optical cavity, where the pulses build-up to a higher energy inside of that cavity over the period of many pulses. After the intra-cavity pulses achieve sufficient energy, an active element inside of the cavity switches out the enhanced light pulse with a reduced a repetition rate relative to the pump source. The increased pulse energy and reduced repetition rate will enable the pump source, originally designed for two-photon microscopy, to perform new imaging modalities, such as deep, in-vivo, three-photon microscopy.

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