公开(公告)号：US20180346603A1

公开(公告)日：2018-12-06

申请号：US15779417

申请日：2016-12-01

Applicant: UCB BIOPHARMA SPRL

Inventor： Pallavi BHATTA ,  Laura STARKIE ,  Michael John WRIGHT

IPC: C07K16/46 ,  C07K16/14 ,  C07K14/395 ,  C12N15/10

CPC classification number: C07K16/00 ,  C07K14/395 ,  C07K16/14 ,  C07K16/468 ,  C07K2319/00 ,  C07K2319/21 ,  C07K2319/23

Abstract: The present invention relates to heterodimerically-tethered bispecific protein complexes (according to the general formula of A-X:Y-B) and libraries/multiplexes thereof for use in research and therapy and in particular an in vitro/ex vivo method of detecting synergistic biological function of otherwise unknown pairs of targets.