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公开(公告)号：US20180194856A1
公开(公告)日：2018-07-12
申请号：US15741590
申请日：2016-07-06
Applicant: UCB Biopharma SPRL
Inventor： Robert Anthony GRIFFIN , David Paul HUMPHREYS , Shirley Jane PETERS
CPC classification number: C07K16/32 , A61P35/00 , C07K16/2887 , C07K16/30 , C07K2317/14 , C07K2317/24 , C07K2317/52 , C07K2317/53 , C07K2317/55 , C07K2317/56 , C07K2317/569 , C07K2317/622 , C07K2317/64 , C07K2317/734 , C07K2317/76 , C07K2317/94 , C07K2319/00
Abstract: The invention relates to fusion proteins which bind to human Fc-receptors. The fusion proteins are initially produced as monomers, and are capable of assembly into multimers at a target site of interest. The invention also relates to therapeutic compositions comprising the fusion proteins, and their widespread use in the treatment of diseases.
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公开(公告)号：US20170081406A1
公开(公告)日：2017-03-23
申请号：US15123066
申请日：2015-03-05
Applicant: UCB BIOPHARMA SPRL
Inventor： Farnaz FALLAH-ARANI , Robert Anthony GRIFFIN , David Paul HUMPHREYS , Shirley Jane PETERS , Bryan John SMITH , Paul Edward STEPHENS
IPC: C07K16/28 , A61K45/06 , A61K39/395
CPC classification number: C07K16/283 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K14/70535 , C07K16/00 , C07K2317/41 , C07K2317/51 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/528 , C07K2317/53 , C07K2317/60 , C07K2317/66 , C07K2317/76 , C07K2317/92 , C07K2319/00
Abstract: The invention relates to multimeric fusion proteins which bind to human Fc receptors. The invention also relates to therapeutic compositions comprising the proteins, and their use in the treatment of immune disorders.
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公开(公告)号：US20170029505A1
公开(公告)日：2017-02-02
申请号：US15303625
申请日：2015-04-16
Applicant: UCB BIOPHARMA SPRL
Inventor： Robert Anthony GRIFFIN , David Paul HUMPHREYS , Shirley Jane PETERS
CPC classification number: C07K16/283 , A61K2039/505 , C07K16/00 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3053 , C07K16/3061 , C07K16/3069 , C07K2317/22 , C07K2317/524 , C07K2317/526 , C07K2317/528 , C07K2317/53 , C07K2317/569 , C07K2317/622 , C07K2317/72 , C07K2317/76 , C07K2319/30
Abstract: The invention relates to multimeric proteins which bind to human Fc receptors. The invention also relates to therapeutic compositions comprising the proteins, and their use in the treatment of immune and other disorders.
Abstract translation: 本发明涉及结合人Fc受体的多聚体蛋白质。 本发明还涉及包含蛋白质的治疗组合物及其在治疗免疫和其它疾病中的用途。
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公开(公告)号：US20170088603A1
公开(公告)日：2017-03-30
申请号：US15123038
申请日：2015-03-05
Applicant: UCB BIOPHARMA SPRL
Inventor： Farnaz FALLAH-ARANI , Robert Anthony GRIFFIN , David Paul HUMPHREYS , Shirley Jane PETERS , Bryan John SMITH , Paul Edward STEPHENS
CPC classification number: C07K16/00 , A61K2039/505 , C07K16/46 , C07K2317/41 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/528 , C07K2317/53 , C07K2317/62 , C07K2317/76 , C07K2317/92 , C12N15/62 , C12P21/02
Abstract: The invention relates to multimeric fusion proteins which bind to human Fc receptors. The invention also relates to therapeutic compositions comprising the proteins, and their use in the treatment of immune disorders.
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