公开(公告)号：US20190270811A1

公开(公告)日：2019-09-05

申请号：US16299407

申请日：2019-03-12

Applicant: UCB BIOPHARMA SPRL

Inventor： Paul Alan ATHERFOLD ,  Thomas Allen CESKA ,  Helene Margaret FINNEY ,  Lara KEVORKIAN ,  Kaushik SARKAR ,  Bryan John SMITH ,  Kerry Louise TYSON

IPC: C07K16/28 ,  A61K47/68 ,  A61K47/60

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：US20170081406A1

公开(公告)日：2017-03-23

申请号：US15123066

申请日：2015-03-05

Applicant: UCB BIOPHARMA SPRL

Inventor： Farnaz FALLAH-ARANI ,  Robert Anthony GRIFFIN ,  David Paul HUMPHREYS ,  Shirley Jane PETERS ,  Bryan John SMITH ,  Paul Edward STEPHENS

IPC: C07K16/28 ,  A61K45/06 ,  A61K39/395

CPC classification number: C07K16/283 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505 ,  C07K14/70535 ,  C07K16/00 ,  C07K2317/41 ,  C07K2317/51 ,  C07K2317/52 ,  C07K2317/524 ,  C07K2317/526 ,  C07K2317/528 ,  C07K2317/53 ,  C07K2317/60 ,  C07K2317/66 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2319/00

Abstract: The invention relates to multimeric fusion proteins which bind to human Fc receptors. The invention also relates to therapeutic compositions comprising the proteins, and their use in the treatment of immune disorders.

公开(公告)号：US20160264668A1

公开(公告)日：2016-09-15

申请号：US15036209

申请日：2014-11-12

Applicant: UCB BIOPHARMA SPRL

Inventor： Paul Alan ATHERFOLD ,  Thomas Allen CESKA ,  Helene Margaret FINNEY ,  Lara KEVORKIAN ,  Kaushik SARKAR ,  Bryan John SMITH ,  Kerry Louise TYSON

IPC: C07K16/28 ,  A61K47/48

CPC classification number: C07K16/283 ,  A61K47/60 ,  A61K47/6849 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/51 ,  C07K2317/515 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/624 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

Abstract translation: 本公开涉及对FcRn特异性的抗体，包含其的制剂，治疗中的每一种的使用，用于表达和任选配制所述抗体的方法，编码抗体的DNA和包含所述DNA的宿主。

公开(公告)号：US20220162311A1

公开(公告)日：2022-05-26

申请号：US17643506

申请日：2021-12-09

Applicant: UCB BIOPHARMA SPRL

Inventor： Paul Alan ATHERFOLD ,  Thomas Allen CESKA ,  Helene Margaret FINNEY ,  Lara KEVORKIAN ,  Kaushik SARKAR ,  Bryan John SMITH ,  Kerry Louise TYSON

IPC: C07K16/28 ,  A61K47/68 ,  A61K47/60

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：US20180127498A1

公开(公告)日：2018-05-10

申请号：US15573185

申请日：2016-05-09

Applicant: UCB Biopharma SPRL

Inventor： Pallavi BHATTA ,  Emma DAVE ,  Sam Philip HEYWOOD ,  David Paul HUMPHREYS ,  Bryan John SMITH

IPC: C07K16/28 ,  C07K16/18 ,  A61P21/04 ,  A61P17/00 ,  A61P25/00 ,  A61P37/00 ,  A61P7/00

CPC classification number: C07K16/283 ,  A61K2039/505 ,  A61P7/00 ,  A61P17/00 ,  A61P21/04 ,  A61P25/00 ,  A61P37/00 ,  C07K16/18 ,  C07K16/28 ,  C07K2317/24 ,  C07K2317/30 ,  C07K2317/31 ,  C07K2317/33 ,  C07K2317/35 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/624 ,  C07K2317/626 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94 ,  C07K2319/74

Abstract: The disclosure relates to antibody fusion proteins specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：US20170088603A1

公开(公告)日：2017-03-30

申请号：US15123038

申请日：2015-03-05

Applicant: UCB BIOPHARMA SPRL

Inventor： Farnaz FALLAH-ARANI ,  Robert Anthony GRIFFIN ,  David Paul HUMPHREYS ,  Shirley Jane PETERS ,  Bryan John SMITH ,  Paul Edward STEPHENS

IPC: C07K16/00 ,  C12P21/02 ,  C12N15/62

CPC classification number: C07K16/00 ,  A61K2039/505 ,  C07K16/46 ,  C07K2317/41 ,  C07K2317/52 ,  C07K2317/524 ,  C07K2317/526 ,  C07K2317/528 ,  C07K2317/53 ,  C07K2317/62 ,  C07K2317/76 ,  C07K2317/92 ,  C12N15/62 ,  C12P21/02

Abstract: The invention relates to multimeric fusion proteins which bind to human Fc receptors. The invention also relates to therapeutic compositions comprising the proteins, and their use in the treatment of immune disorders.