公开(公告)号：US20250107747A1

公开(公告)日：2025-04-03

申请号：US18899233

申请日：2024-09-27

Applicant: UNIVERSITY HEALTH NETWORK

Inventor： Nooshin BAHADOR ,  Liang ZHANG ,  Frances SKINNER ,  Milad LANKARANY

IPC: A61B5/00 ,  G16H20/10 ,  G16H50/20

Abstract: According to an aspect, there is provided a computer implemented method and an epilepsy monitoring unit for diagnosis, investigation or treatment of seizures. The method includes identifying ictal-related chirp patterns from recordings of electrophysiological signals by determining onset and offset times of the ictal-related chirp patterns, characterizing the ictal-related chirp patterns, classifying spectro-temporal morphology of the ictal-related chirp patterns. According to an aspect, there is provided a computer implemented method for electrophysiological signals. The method including extracting a neuromarker from neural activities recorded as electrophysiological signals and characterizing ictal-related patterns in the electrophysiological signals during ictal discharge. The neuromarker is for assessment of progression of a seizure or efficacy of anti-seizure pharmacological agents.