公开(公告)号：US11814526B2

公开(公告)日：2023-11-14

申请号：US18079085

申请日：2022-12-12

Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION

Inventor： Elise Lin Cheng ,  C. Allan Guymon ,  Marian R. Hansen ,  Braden Leigh

IPC: C09D133/10 ,  A61L27/16 ,  A61L27/34 ,  A61L29/04 ,  A61L29/08 ,  A61L31/04 ,  A61L31/10 ,  C08K5/11 ,  C09D5/16 ,  C09D133/26 ,  C09D151/08

CPC classification number: C09D133/10 ,  A61L27/16 ,  A61L27/34 ,  A61L29/041 ,  A61L29/085 ,  A61L31/048 ,  A61L31/10 ,  C08K5/11 ,  C09D5/1675 ,  C09D133/26 ,  C09D151/085 ,  A61L2300/404 ,  A61L2420/08

Abstract: Durable, anti-fouling, crosslinked zwitterionic coatings that are grafted to the surface of a substrate through covalent bonding are disclosed. When exposed to a light source, zwitterionic monomers react with a crosslinker and with activated radicals at the surface of the substrate, simultaneously forming the crosslinked zwitterionic coating and anchoring it to the surface of the substrate. Photomasking techniques can be used to micropattern the zwitterionic coatings. The zwitterionic coatings can be applied to a variety of substrates, including medical devices and systems.

公开(公告)号：US20240084163A1

公开(公告)日：2024-03-14

申请号：US18507969

申请日：2023-11-13

Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION

Inventor： Elise Lin Cheng ,  C. Allan Guymon ,  Marlan R. Hansen ,  Braden Leigh

IPC: C09D133/10 ,  A61L27/16 ,  A61L27/34 ,  A61L29/04 ,  A61L29/08 ,  A61L31/04 ,  A61L31/10 ,  C08K5/11 ,  C09D5/16 ,  C09D133/26 ,  C09D151/08

CPC classification number: C09D133/10 ,  A61L27/16 ,  A61L27/34 ,  A61L29/041 ,  A61L29/085 ,  A61L31/048 ,  A61L31/10 ,  C08K5/11 ,  C09D5/1675 ,  C09D133/26 ,  C09D151/085 ,  A61L2300/404 ,  A61L2420/08

Abstract: Durable, anti-fouling, crosslinked zwitterionic coatings that are grafted to the surface of a substrate through covalent bonding are disclosed. When exposed to a light source, zwitterionic monomers react with a crosslinker and with activated radicals at the surface of the substrate, simultaneously forming the crosslinked zwitterionic coating and anchoring it to the surface of the substrate. Photomasking techniques can be used to micropattern the zwitterionic coatings. The zwitterionic coatings can be applied to a variety of substrates, including medical devices and systems.

公开(公告)号：US11525069B2

公开(公告)日：2022-12-13

申请号：US16312448

申请日：2017-06-24

Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION

Inventor： Elise Lin Cheng ,  C. Allan Guymon ,  Marian R. Hansen ,  Braden Leigh

IPC: C09D133/10 ,  A61L27/16 ,  A61L27/34 ,  A61L29/04 ,  A61L29/08 ,  A61L31/04 ,  A61L31/10 ,  C08K5/11 ,  C09D5/16 ,  C09D133/26 ,  C09D151/08

Abstract: Durable, anti-fouling, crosslinked zwitterionic coatings that are grafted to the surface of a substrate through covalent bonding are disclosed. When exposed to a light source, zwitterionic monomers react with a crosslinker and with activated radicals at the surface of the substrate, simultaneously forming the crosslinked zwitterionic coating and anchoring it to the surface of the substrate. Photomasking techniques can be used to micropattern the zwitterionic coatings. The zwitterionic coatings can be applied to a variety of substrates, including medical devices and systems.

公开(公告)号：US12116498B2

公开(公告)日：2024-10-15

申请号：US18507969

申请日：2023-11-13

Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION

Inventor： Elise Lin Cheng ,  C. Allan Guymon ,  Marlan R. Hansen ,  Braden Leigh

IPC: C09D133/10 ,  A61L27/16 ,  A61L27/34 ,  A61L29/04 ,  A61L29/08 ,  A61L31/04 ,  A61L31/10 ,  C08K5/11 ,  C09D5/16 ,  C09D133/26 ,  C09D151/08

CPC classification number: C09D133/10 ,  A61L27/16 ,  A61L27/34 ,  A61L29/041 ,  A61L29/085 ,  A61L31/048 ,  A61L31/10 ,  C08K5/11 ,  C09D5/1675 ,  C09D133/26 ,  C09D151/085 ,  A61L2300/404 ,  A61L2420/08

Abstract: Durable, anti-fouling, crosslinked zwitterionic coatings that are grafted to the surface of a substrate through covalent bonding are disclosed. When exposed to a light source, zwitterionic monomers react with a crosslinker and with activated radicals at the surface of the substrate, simultaneously forming the crosslinked zwitterionic coating and anchoring it to the surface of the substrate. Photomasking techniques can be used to micropattern the zwitterionic coatings. The zwitterionic coatings can be applied to a variety of substrates, including medical devices and systems.

公开(公告)号：US20200308440A1

公开(公告)日：2020-10-01

申请号：US16312448

申请日：2017-06-24

Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION

Inventor： Elise Lin Cheng ,  C. Allan Guymon ,  Marlan R. Hansen ,  Braden Leigh

IPC: C09D133/10 ,  C09D5/16 ,  C08K5/11 ,  A61L27/34 ,  A61L29/08 ,  A61L31/10 ,  C09D133/26 ,  A61L29/04 ,  A61L31/04 ,  A61L27/16 ,  C09D151/08

Abstract: Durable, anti-fouling, crosslinked zwitterionic coatings that are grafted to the surface of a substrate through covalent bonding are disclosed. When exposed to a light source, zwitterionic monomers react with a crosslinker and with activated radicals at the surface of the substrate, simultaneously forming the crosslinked zwitterionic coating and anchoring it to the surface of the substrate. Photomasking techniques can be used to micropattern the zwitterionic coatings. The zwitterionic coatings can be applied to a variety of substrates, including medical devices and systems.