公开(公告)号：US20170258967A1

公开(公告)日：2017-09-14

申请号：US15118414

申请日：2015-02-13

Applicant: UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION

Inventor： Warren O. HAGGARD ,  Ashley C. PARKER ,  Jessica Amber JENNINGS

IPC: A61L29/16 ,  A61K47/10 ,  A61L29/08 ,  A61L29/04 ,  A61L29/14 ,  C08J5/18 ,  A61K9/00 ,  A61K38/14 ,  A61K31/7036 ,  C08L5/08 ,  C08L71/02 ,  A61K47/36 ,  A61K31/7048

CPC classification number: A61L29/16 ,  A61K9/0024 ,  A61K9/19 ,  A61K31/7036 ,  A61K31/7048 ,  A61K38/14 ,  A61K47/10 ,  A61K47/36 ,  A61L15/26 ,  A61L15/28 ,  A61L15/425 ,  A61L15/44 ,  A61L17/005 ,  A61L17/06 ,  A61L17/10 ,  A61L29/049 ,  A61L29/085 ,  A61L29/146 ,  A61L29/148 ,  A61L2300/232 ,  A61L2300/252 ,  A61L2300/404 ,  A61L2300/606 ,  A61L2420/06 ,  C08J5/18 ,  C08J9/0061 ,  C08J9/28 ,  C08J2201/0484 ,  C08J2205/022 ,  C08J2207/10 ,  C08J2305/08 ,  C08J2371/02 ,  C08J2471/02 ,  C08L5/08 ,  C08L71/02 ,  C08L2203/02

Abstract: The invention provides compositions featuring chitosan and polyethylene glycol and methods for using such compositions for the local delivery of biologically active agents to an open fracture, complex wound or other site of infection. Advantageously, the chitosan-PEG compositions can be loaded with one or more antimicrobial agents, including hydrophobic agents, and can be tailored to the needs of particular patients at the point of care (e.g., in a surgical suite, clinic, physician's office, or other clinical setting).

公开(公告)号：US20230226190A1

公开(公告)日：2023-07-20

申请号：US18102123

申请日：2023-01-27

Applicant: The University of Memphis Research Foundation

Inventor： Warren O. HAGGARD ,  Scott P. NOEL ,  Joel D. BUMGARDNER

IPC: A61K47/36 ,  A61L31/16 ,  A61L31/14 ,  A61K9/70 ,  A61L31/04 ,  A61L27/58 ,  A61L15/44 ,  A61K31/7036 ,  A61L29/14 ,  A61K31/00 ,  A61K38/14 ,  A61L29/16 ,  C08J5/18 ,  C08B37/08 ,  A61L15/28 ,  C08L5/08 ,  A61L29/04 ,  A61L27/20 ,  A61K9/00

CPC classification number: A61K47/36 ,  A61L31/16 ,  A61L31/148 ,  A61K9/7007 ,  A61L31/042 ,  A61L27/58 ,  A61L15/44 ,  A61K31/7036 ,  A61L29/148 ,  A61K31/00 ,  A61K38/14 ,  A61L29/146 ,  A61L29/16 ,  A61L31/146 ,  C08J5/18 ,  C08B37/003 ,  A61L15/28 ,  C08L5/08 ,  A61L29/043 ,  A61L27/20 ,  A61L2300/232 ,  A61K9/0024 ,  A61L2300/406 ,  C08J2305/08 ,  A61L2300/25

Abstract: The invention provides compositions featuring chitosan and methods for using such compositions for the local delivery of biologically active agents to an open fracture, complex wound or other site of infection. Advantageously, the degradation and drug elution profiles of the chitosan compositions can be tailored to the needs of particular patients at the point of care (e.g., in a surgical suite, clinic, physician's office, or other clinical setting).