公开(公告)号：US20250049338A1

公开(公告)日：2025-02-13

申请号：US18719461

申请日：2022-12-12

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： ASHWIN PARTHASARATHY ,  ABDUL MOHAIMEN SAFI

IPC: A61B5/026 ,  A61B5/00 ,  G06T7/00 ,  G06T7/20

Abstract: A SyntheticMulti-Exposure Speckle Imaging (syMESI) methodology necessarily utilizing an optical interferometer apparatus as part of the speckle imaging system to overcome the optical detector noise that conventionally limits the reliable and accurate determination of a speckle contrast characteristic at low exposure times. The use of such methodology enabled a quantitative determination of absolute value(s) of changes of motion at the target object (such as blood flow changes in tissue) at low photon budget of less than 40 counts of average detection intensity and/or quantitative imaging of the blood flow at the object in interoperative setting with a low-cost camera sensor.