公开(公告)号：US11181482B1

公开(公告)日：2021-11-23

申请号：US16121932

申请日：2018-09-05

Applicant: University of South Florida

Inventor： Anna Pyayt ,  Arsenii Zhdanov ,  Jordan Keefe ,  Luis Franco-Waite

IPC: G01N21/78 ,  G01N21/25 ,  G01N21/64 ,  G01N21/27 ,  G01N33/543 ,  G01N21/03 ,  G01N21/29 ,  G01N33/569 ,  G01N33/574

Abstract: A mobile phone-based system for ELISA (MELISA). The MELISA system can perform all steps of ELISA procedure and output hormone concentration values. The system includes a heater that keeps the temperature required for sample incubation, illumination system for sample image capturing, and a digital camera system. All components are enclosed in a dark box to create optimal light conditions for image capturing. After sample images are captured, they are digitally processed, and hormone concentration values are reported based on colorimetric data from the samples. The system can be used to complete all steps of the assay, including incubation and reading. It is lightweight, can be fabricated at low cost, is portable, and can transfer test results via mobile phone. MELISA can be calibrated for accurate measurements of progesterone and has demonstrated successful measurements with the calibrated system.

公开(公告)号：US20160151493A1

公开(公告)日：2016-06-02

申请号：US14778703

申请日：2015-06-03

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Anna Pyayt

IPC: A61K41/00 ,  A61K47/48 ,  A61K9/00 ,  A61N5/06 ,  A61B18/04

CPC classification number: A61K41/0052 ,  A61B18/04 ,  A61B18/18 ,  A61K9/0019 ,  A61K41/00 ,  A61K47/52 ,  A61K47/6941 ,  A61N5/062 ,  A61N2005/0659 ,  C22C5/02

Abstract: In one embodiment, a heating element includes a central particle and a plurality of plasmonic nanoparticles attached to the central particle, wherein the nanoparticles undergo plasmonic heating when exposed to near infrared light.

Abstract translation: 在一个实施方案中，加热元件包括中心颗粒和附着到中心颗粒的多个等离子体激元纳米颗粒，其中当暴露于近红外光时，纳米颗粒经受等离子体激发加热。

公开(公告)号：US20220236169A1

公开(公告)日：2022-07-28

申请号：US17723128

申请日：2022-04-18

Applicant: University of South Florida

Inventor： Anna Pyayt ,  Edikan Archibong ,  Harry Tuazon

IPC: G01N21/31 ,  G01N1/40 ,  B01L3/00

Abstract: An optical spectroscopy probe including an optical fiber having a distal tip and a microfluidic filtering chamber attached to the distal tip of the optical fiber, the chamber comprising a microfluidic membrane configured to enable liquid to enter the chamber but prevent particles from entering the chamber. Method for fabrication of same.

公开(公告)号：US11307194B2

公开(公告)日：2022-04-19

申请号：US15311216

申请日：2015-05-18

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Anna Pyayt ,  Edikan Archibong ,  Harry Tuazon

IPC: B01L3/00 ,  A61B5/1455 ,  G02B6/36 ,  G01N33/49 ,  A61B5/00 ,  G01N21/39 ,  B01D63/00

Abstract: In one embodiment, an optical spectroscopy probe includes an optical fiber having a distal tip and a microfluidic filtering chamber attached to the distal tip of the optical fiber, the chamber comprising a microfluidic membrane adapted to enable liquid to enter the chamber but prevent particles from entering the chamber.

公开(公告)号：US20170082602A1

公开(公告)日：2017-03-23

申请号：US15311216

申请日：2015-05-18

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Anna Pyayt ,  Edikan Archibong ,  Harry Tuazon

IPC: G01N33/49 ,  G01N21/39 ,  B01L3/00

CPC classification number: G01N33/49 ,  A61B5/1455 ,  A61B5/14552 ,  A61B5/4244 ,  B01L3/502715 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/168 ,  G01N21/39 ,  G01N2201/06113 ,  G01N2201/0846

Abstract: In one embodiment, an optical spectroscopy probe includes an optical fiber having a distal tip and a microfluidic filtering chamber attached to the distal tip of the optical fiber, the chamber comprising a microfluidic membrane adapted to enable liquid to enter the chamber but prevent particles from entering the chamber.