公开(公告)号：US20230002381A1

公开(公告)日：2023-01-05

申请号：US17850650

申请日：2022-06-27

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Yu CHEN ,  Michael SACCO ,  James LEAHY ,  Elena BRAY ,  Xingmin SUN ,  Xiujun ZHANG

IPC: C07D471/08 ,  A61K45/06

Abstract: Disclosed herein are compounds that can prevent and treat C. difficile by inhibiting sporulation. Also disclosed herein are compositions and formulations comprising the compound disclosed herein. Methods of preventing and treating C. difficile comprising administering the compounds described herein are also disclosed.

公开(公告)号：US20240051959A1

公开(公告)日：2024-02-15

申请号：US18376525

申请日：2023-10-04

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Yu CHEN ,  Michael SACCO ,  James LEAHY ,  Elena BRAY ,  Xingmin SUN ,  Xiujun ZHANG

IPC: C07D471/08 ,  A61K45/06

CPC classification number: C07D471/08 ,  A61K45/06

Abstract: Disclosed herein are compounds that can prevent and treat C. difficile by inhibiting sporulation. Also disclosed herein are compositions and formulations comprising the compound disclosed herein. Methods of preventing and treating C. difficile comprising administering the compounds described herein are also disclosed.