公开(公告)号：US20230172970A1

公开(公告)日：2023-06-08

申请号：US18077533

申请日：2022-12-08

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Nurettin Sahiner ,  Ramesh Ayyala

IPC: A61K31/737 ,  A61K9/00 ,  A61K9/50

CPC classification number: A61K31/737 ,  A61K9/0048 ,  A61K9/0014 ,  A61K9/5015

Abstract: Disclosed herein are crosslinked chondroitin sulfate particles crosslinked chondroitin sulfate particle polyelectrolytes. The particles are useful in drug delivery applications. The particles may be used to treat various conditions, including bacterial and fungal infections.

公开(公告)号：US20240043618A1

公开(公告)日：2024-02-08

申请号：US18380965

申请日：2023-10-17

Applicant: University of South Florida

Inventor： Ramesh Ayyala ,  Nurettin Sahiner

IPC: C08G73/02 ,  A61P31/04 ,  A01P1/00

CPC classification number: C08G73/0273 ,  C08G73/0246 ,  A61P31/04 ,  A01P1/00

Abstract: This disclosure relates to antimicrobial compositions, and more particularly to treatment of surfaces (e.g., face masks) for the reduction or prevention of transmission of microbes (e.g., bacteria, fungus, and/or viruses). In some embodiments, the compositions comprise a cationic polymer selected from the group consisting of: a polydiallyldimethylammonium salt, a polyethyleneimine salt, a polydiallyldimethylammonium with different counter ions, a chemically modified polyethyleneimine salt, or a combination thereof.

公开(公告)号：US11998562B2

公开(公告)日：2024-06-04

申请号：US17583781

申请日：2022-01-25

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Vijaykumar Sutariya ,  Srinivas Tipparaju ,  Kevin Sneed ,  Manas Biswal ,  Ramesh Ayyala ,  Radouil Tzekov

IPC: A61K31/706 ,  A61K9/00 ,  A61K31/573

CPC classification number: A61K31/706 ,  A61K9/0048 ,  A61K31/573

Abstract: The present disclosure provides for an ophthalmological composition comprising remdesivir and an ophthalmologically suitable carrier, and the use thereof for treating and preventing a coronavirus infection and treating conjunctivitis.

公开(公告)号：US20220233564A1

公开(公告)日：2022-07-28

申请号：US17583781

申请日：2022-01-25

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Vijaykumar Sutariya ,  Srinivas Tipparaju ,  Kevin Sneed ,  Manas Biswal ,  Ramesh Ayyala ,  Radouil Tzekov

IPC: A61K31/706 ,  A61K9/00 ,  A61K31/573

Abstract: The present disclosure provides for an ophthalmological composition comprising remdesivir and an ophthalmologically suitable carrier, and the use thereof for treating and preventing a coronavirus infection and treating conjunctivitis.

公开(公告)号：US12171779B2

公开(公告)日：2024-12-24

申请号：US18077533

申请日：2022-12-08

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Nurettin Sahiner ,  Ramesh Ayyala

IPC: A61K31/737 ,  A61K9/00 ,  A61K9/50

Abstract: Disclosed herein are crosslinked chondroitin sulfate particles crosslinked chondroitin sulfate particle polyelectrolytes. The particles are useful in drug delivery applications. The particles may be used to treat various conditions, including bacterial and fungal infections.