公开(公告)号：US20240100334A1

公开(公告)日：2024-03-28

申请号：US17766600

申请日：2020-10-28

Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA

Inventor： Mark S. Humayun ,  Gianluca Lazzi ,  Bodour Salhia ,  Manjunath Machnoor ,  Javad Paknahad

IPC: A61N1/36 ,  A61N1/04 ,  A61N1/40 ,  C12Q1/6874 ,  C12Q1/6883

CPC classification number: A61N1/36046 ,  A61N1/0476 ,  A61N1/36014 ,  A61N1/40 ,  C12Q1/6874 ,  C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/154

Abstract: Methods, systems, and apparatus for causing changes to cells or tissue within or adjacent to an eye. The system includes an external RF coil configured to transmit RF signals. The system also includes a wearable device configured to be removably disposed on the eye, the wearable device including a plurality of internal radiofrequency (RF) coils configured to receive the RF signals from the external RF coil and a plurality of stimulating electrodes configured to electromagnetically stimulate a portion of the eye or an area adjacent to the eye, causing changes to cells or tissue within or adjacent to the eye.

公开(公告)号：US20220280777A1

公开(公告)日：2022-09-08

申请号：US17685186

申请日：2022-03-02

Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA

Inventor： Mark S. Humayun ,  Gianluca Lazzi ,  Bodour Salhia ,  Manjunath Machnoor ,  Javad Paknahad ,  Alejandra Gonzalez-Calle ,  Ben Yi Tew

IPC: A61N1/04 ,  A61N1/05 ,  A61N1/40 ,  A61N1/14

Abstract: Bioelectronic lens (E-lens) systems for inducing neuroprotective changes in neurons, in particular the retina. A system may include a stimulating electrode configured to be placed on an eye or skin around the eye. The system may further include a return electrode configured such that voltage distribution is focalized to the eye and induced electric fields to an area of interest on the eye or on the skin around the eye are maximized. The electric fields provide neuroprotection and reinnervation.