公开(公告)号：US20240166683A1

公开(公告)日：2024-05-23

申请号：US18503951

申请日：2023-11-07

Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA ,  RADBOUD UNIVERSITY NIJMEGEN

Inventor： Zhipeng LU ,  Willem A. VELEMA ,  Ryan VAN DAMME

IPC: C07H21/02 ,  C12N15/11

CPC classification number: C07H21/02 ,  C12N15/111 ,  C12N2310/351 ,  C12N2320/51

Abstract: Reversible Spatial 2′ Hydroxyl Acylation Reversible Crosslinking (SHARC) agents and methods of using the same to determine spatial distance between nucleotides in a ribonucleic acid (RNA) molecule.