公开(公告)号：US07645267B2

公开(公告)日：2010-01-12

申请号：US10535760

申请日：2003-11-19

Applicant: Udo J. Vetter ,  Joachim Glocker ,  Jochen Alberstetter

Inventor： Udo J. Vetter ,  Joachim Glocker ,  Jochen Alberstetter

IPC: A61M5/315

CPC classification number: A61M5/286 ,  A61M5/28 ,  A61M5/3146 ,  A61M5/347 ,  A61M5/5086 ,  A61M2005/3104 ,  A61M2005/3106 ,  A61M2005/312

Abstract: A prefilled medical syringe includes a syringe barrel. A syringe plunger is disposed in the barrel and displaceable by means of a plunger rod. An end plug closes off a cannula side of the syringe barrel. The plug is provided with a through-channel closed off by a membrane. A finger support is disposed at the end of the syringe barrel opposite the end plug and provided with a through-opening for the plunger rod. A thread system cooperates with the plunger rod and the finger support. The thread system includes a thread sleeve detachably connected with the finger support. The thread sleeve is provided with an inner thread that cooperates with an outer thread on the plunger rod.

Abstract translation: 预充式医疗注射器包括注射器筒。 注射器柱塞设置在筒体中并且可通过柱塞杆移动。 终端塞将注射器筒的插管侧封闭。 插头设有通过膜封闭的通道。 手指支撑件设置在与端塞相对的注射器筒的端部处并且设置有用于柱塞杆的通孔。 螺纹系统与柱塞杆和手指支撑件配合。 螺纹系统包括可拆卸地与手指支撑件连接的螺纹套筒。 螺纹套筒具有与柱塞杆上的外螺纹配合的内螺纹。

公开(公告)号：US07036288B2

公开(公告)日：2006-05-02

申请号：US10779527

申请日：2004-02-12

Applicant: Udo J. Vetter ,  Helmut Hennig

Inventor： Udo J. Vetter ,  Helmut Hennig

IPC: B65B57/02

CPC classification number: B65B3/003

Abstract: Prefilled syringes are made by displacing a succession of syringes along a conveyor path from a supply station successively through a marking station, a filling station, and to a downstream packing station. Each of the syringes is filled with a predetermined dose of a medicament in the filling station. The syringes are marked in the marking station with machine-readable data identifying the medicament to be put in the empty syringe at the filling station. The syringes are scanned downstream of the marking station and any syringe whose data is not readable is then removed from the conveyor path, as is any syringe whose data does not correspond to the medicament filled into the syringe at the filling station.

Abstract translation: 预先注射的注射器是通过将一连串注射器沿输送路径从供应站连续地通过标记站，加油站和下游包装站排出的。 每个注射器在加油站中填充有预定剂量的药物。 注射器在标记站中标记有机器可读数据，标识要在加油站放置在空注射器中的药物。 注射器被扫描在标记站的下游，并且其数据不可读的任何注射器然后从输送路径中移除，其中任何注射器的数据与填充到注射器中的药物不对应。

公开(公告)号：US06419656B1

公开(公告)日：2002-07-16

申请号：US09528513

申请日：2000-03-20

Applicant: Udo J. Vetter ,  Klaus Schönwetter

Inventor： Udo J. Vetter ,  Klaus Schönwetter

IPC: A61M300

CPC classification number: A61M5/31595 ,  A61M5/284 ,  A61M5/3146 ,  A61M5/31505 ,  A61M5/31553 ,  A61M5/3156 ,  A61M5/3158 ,  A61M2005/3139 ,  A61M2005/3151

Abstract: A medical syringe has a tubular body extending along an axis and having a front end and a rear end, a plunger axially slidable in the body and carrying a stem projecting axially rearward out of the body from the plunger, and a free piston slidable in the body forward of the plunger and subdividing the body forward of the plunger into a front compartment at the front body end and a rear compartment between the plunger and the piston. The body is formed with a bypass passage forward of the piston in a starting position so the front compartment can hold a soluble medicament and the rear compartment can hold its solvent. Structure at the rear body end forms a radially inwardly open angularly limited cutout and at least two axially spaced, angularly offset, and radially outwardly projecting stop bumps on the stem are axially displaceable through the cutout in respective angularly offset positions of the stem. The stop bumps are axially engageable against the structure except when the stem is in the respective angular position. An elastically deformable brake element engaged between the body and the stem for axially slowing axial forward advance of the stem.

Abstract translation: 医疗注射器具有沿着轴线延伸并具有前端和后端的管状体，可在主体中可轴向滑动的柱塞，并且从柱塞沿轴向向后伸出体外的杆，以及可自由滑动的自由活塞 柱塞的前部并将柱塞的前部细分成前体的前隔室和柱塞与活塞之间的后隔间。 主体在起始位置形成有活塞前方的旁路通道，因此前隔室可容纳可溶性药物，后隔室可容纳其溶剂。 在后主体端部处的结构形成径向向内开口的有角度限制的切口，并且柄上的至少两个轴向间隔开的有角度偏移和径向向外突出的止动凸块在杆的相应的角度偏移位置中可轴向移动穿过切口。 除了杆处于相应的角位置之外，止动凸块可轴向地接合结构。 接合在主体和杆之间的可弹性变形的制动元件用于轴向地减慢杆的轴向前进。

公开(公告)号：US20110046563A1

公开(公告)日：2011-02-24

申请号：US12907774

申请日：2010-10-19

Applicant: Udo J. Vetter ,  Joachim Glocker ,  Walter Schwarz

Inventor： Udo J. Vetter ,  Joachim Glocker ,  Walter Schwarz

IPC: A61M5/31 ,  A61M5/32 ,  A61M5/315

CPC classification number: A61M5/31511 ,  A61L2/07 ,  A61L2/18 ,  A61L2/20 ,  A61L2/26 ,  A61L2202/121 ,  A61L2202/21 ,  A61M2005/3104

Abstract: A sealing element is suggested, in particular one for closing primary packaging for medications, that has at least two parts, which touch each other at least in some areas. This is characterized in that steam-permeable channels are provided for sterilization of the contact surfaces. In addition, a method is suggested for manufacturing a syringe system with a sealing element. This is characterized by the steps preliminary assembly of the sealing element, sterilization of the sealing element, final assembly of the sealing element.

Abstract translation: 建议使用密封元件，特别是用于封闭用于药物的初级包装的密封元件，其具有至少两部分，至少在一些区域彼此接触。 其特征在于提供透气通道用于对接触表面进行灭菌。 此外，建议制造具有密封元件的注射器系统的方法。 其特征在于密封元件的初步组装，密封元件的灭菌，密封元件的最终组装。

公开(公告)号：US07828777B2

公开(公告)日：2010-11-09

申请号：US10479206

申请日：2002-05-18

Applicant: Udo J. Vetter ,  Joachim Glocker ,  Walter Schwarz

Inventor： Udo J. Vetter ,  Joachim Glocker ,  Walter Schwarz

IPC: A61M5/32 ,  A61B19/00

CPC classification number: A61M5/31511 ,  A61L2/07 ,  A61L2/18 ,  A61L2/20 ,  A61L2/26 ,  A61L2202/121 ,  A61L2202/21 ,  A61M2005/3104

Abstract: A sealing element is suggested, in particular one for closing primary packaging for medications, that has at least two parts, which touch each other at least in some areas. This is characterized in that steam-permeable channels are provided for sterilization of the contact surfaces. In addition, a method is suggested for manufacturing a syringe system with a sealing element. This is characterized by the steps—preliminary assembly of the sealing element, —sterilization of the sealing element, —final assembly of the sealing element.

Abstract translation: 建议使用密封元件，特别是用于封闭用于药物的初级包装的密封元件，其具有至少两部分，至少在一些区域彼此接触。 其特征在于提供透气通道用于对接触表面进行灭菌。 此外，建议制造具有密封元件的注射器系统的方法。 其特征在于密封元件的初步组装，密封元件的灭菌，密封元件的最终组件。

公开(公告)号：US06491665B1

公开(公告)日：2002-12-10

申请号：US09516651

申请日：2000-03-01

Applicant: Udo J. Vetter ,  Thomas Otto ,  Petra Hund

Inventor： Udo J. Vetter ,  Thomas Otto ,  Petra Hund

IPC: A61M500

CPC classification number: A61M5/3134 ,  A61M5/3213 ,  A61M5/5086

Abstract: A syringe assembly has a syringe body adapted to be filled with an injectable liquid and having an annular neck defining an axis and having an axially outwardly open outlet. The neck is adapted to carry a needle. An elastomeric plug engaged axially inward with the neck closes the outlet and a holding ring is fixed to the neck below the plug. A retaining sleeve around the neck is fixed to the holding ring and a cup-shaped safety cap is fixed to the plug and has an end edge confronting the retaining sleeve and spaced axially therefrom. Frangible formations extend from the cap edge to the sleeve.

Abstract translation: 注射器组件具有适于填充有可注射液体并且具有限定轴线并具有轴向向外开口的出口的环形颈部的注射器主体。 颈部适合携带针头。 与颈部轴向向内接合的弹性塞子封闭出口，并且保持环固定在塞子下方的颈部。 围绕颈部的保持套固定在保持环上，并且杯形安全帽固定在插头上，并且具有面向保持套筒并与其轴向间隔的端部边缘。 易碎结构从帽边缘延伸到套筒。

公开(公告)号：US06223408B1

公开(公告)日：2001-05-01

申请号：US09624479

申请日：2000-07-24

Applicant: Udo J. Vetter ,  Klaus Steinbach ,  Anton Hecht

Inventor： Udo J. Vetter ,  Klaus Steinbach ,  Anton Hecht

IPC: B23P1904

CPC classification number: B65B61/207 ,  A61M5/2448 ,  A61M5/284 ,  B65B3/003 ,  B65B7/2821 ,  Y10T29/53652 ,  Y10T29/53657 ,  Y10T29/53943

Abstract: An object, e.g. a piston or a fluid medicament, is inserted into a tubular syringe body centered on a syringe axis and having a pair of ends by an apparatus having a support movable axially forward toward and axially rearward away from the body and a tube extending along a sleeve axis generally parallel to the syringe axis, having a rear end fixed in the support and a front end fittable inside the syringe. A centering sleeve is formed centered on the sleeve axis with a generally frustoconical centering surface engageable with the rear body end surrounding the tube. This sleeve is displaceable axially on the support between a front position with the centering surface projecting axially forward past the tube front end and a rear position with the tube front end projecting axially forward past the centering surface. The support is displaced axially forward toward the body and thereby engages the centering surface coaxially with the body rear end. Thereafter the tube is pressed coaxially through the centering sleeve into the syringe body and the object is expelled from its front end.

Abstract translation: 一个对象，例如 将活塞或流体药物插入到以注射器轴线为中心的管状注射器体内，并且具有一对端部，该装置具有可沿轴向向前并且远离身体轴向向后移动的支撑件，以及沿着套筒轴线延伸的管 通常平行于注射器轴线，其后端固定在支撑件中，前端可装配在注射器内。 中心套筒以套筒轴线为中心形成有大致截头圆锥形的定心表面，可与围绕管子的后体端部接合。 该套筒可以在支撑件之间轴向位移，该前部位置与定心面之间轴向向前突出穿过管子前端，后部位置与管子前端沿轴向向前突出超过定心面。 支撑件朝向主体轴向向前移位，从而与中心面同轴地与主体后端接合。 此后，管被同心地通过定心套筒压入注射器主体中，物体从其前端排出。

公开(公告)号：US06817987B2

公开(公告)日：2004-11-16

申请号：US10222677

申请日：2002-08-16

Applicant: Udo J. Vetter ,  Thomas Otto

Inventor： Udo J. Vetter ,  Thomas Otto

IPC: A61M3700

CPC classification number: A61M5/284 ,  A61M2005/31508

Abstract: A syringe holding a solvent and a soluble component has a tubular body formed its front and rear ends with a bypass, a plunger axially slidable in the body, and a stem projecting axially rearward out of the body from the plunger. A cover fits over the front end of the body and is so tight that the front compartment can be pressurized to a superatmospheric pressure without leakage out the front end. A free piston slidable in the body forward of the plunger subdivides the body forward of the plunger into a front compartment at the front body end holding the soluble component and a rear compartment between the plunger and the piston and holding the solvent. Stops are provided for arresting the free piston when it is level with the bypass in a position permitting flow through the bypass between the compartments.

Abstract translation: 保持溶剂和可溶性成分的注射器具有管状体，其前端和后端具有旁路，可在主体中可轴向滑动的柱塞和从柱塞向轴向后伸出体外的杆。 一个盖子装配在主体的前端，并且非常紧密，使得前隔室可以被加压到超大气压力，而不会从前端泄漏。 在柱塞前部滑动的自由活塞将柱塞的前方的主体细分成前部主体端部的前部隔间，其保持可溶性部件，并且在柱塞和活塞之间并保持溶剂的后部隔室。 提供止动件，用于当自由活塞与旁路平齐时允许流过隔室之间的旁路的位置阻止自由活塞。

公开(公告)号：US06447610B1

公开(公告)日：2002-09-10

申请号：US09618442

申请日：2000-07-18

Applicant: Udo J. Vetter

Inventor： Udo J. Vetter

IPC: B05C100

CPC classification number: A61M5/3129 ,  A61M2005/3131 ,  B05C7/08

Abstract: An inside wall of an elongated syringe body is coated by supplying at least an outer surface of an applicator ring with a coating of silicon oil while displacing a rod carrying the coated ring from a rear end to a front end of the body with the ring in continuous annular engagement with the inside wall thereof so as to transfer the oil from the ring to the inside wall. Thereafter a scraper ring also carried on the rod is displaced from the front end to the rear end of the body with the scraper ring in continuous annular engagement with the inside wall so as to scrape excess silicone oil from the inside wall.

Abstract translation: 通过向涂抹器环的至少外表面供应硅油涂层，同时将携带涂覆环的杆从后端移动到主体的前端，使环的内部位于 与其内壁连续环形接合，以便将油从环转移到内壁。 此后，还带有杆上的刮环从主体的前端移动到后端，刮刀环与内壁连续环形接合，从而从内壁刮去多余的硅油。

公开(公告)号：US5080649A

公开(公告)日：1992-01-14

申请号：US533448

申请日：1990-06-05

Applicant: Udo J. Vetter

Inventor： Udo J. Vetter

IPC: A61M5/178 ,  A61M5/31 ,  A61M5/315 ,  A61M39/00

CPC classification number: A61M5/31596 ,  A61M5/31586

Abstract: A hypodermic syringe has an elongated tubular body having a front end adapted to carry a needle, a rear end, and a bypass between the ends. A front partition piston defines with the front end a front compartment adapted to hold a substance and a rear piston defines with the front piston a rear compartment adapted to hold a fluid miscible with the front-compartment substance. The front piston is displaceable into a middle position in the bypass for fluid communication between the compartments. A stem projecting rearward out of the body from the rear piston is provided with axially spaced front and rear external screwthreads and has a clear region between the screwthreads. A damper on the rear end of the body can engage the screwthreads for slowing axial movement of the screwthreads past the rear end of the body and for permitting relatively rapid axial movement of the stem in the body when the clear region is level with the damper.

Abstract translation: 皮下注射器具有细长管状体，其具有适于承载针头，后端和端部之间的旁路的前端。 前分隔活塞限定前端具有适于保持物质的前隔室，后活塞与前活塞一起形成，后室适于保持与前隔室物质混溶的流体。 前活塞可移动到旁路中的中间位置，以在隔室之间流体连通。 从后活塞向后伸出主体的杆设置有轴向隔开的前外螺纹和后外螺纹，并且在螺纹之间具有清晰的区域。 身体后端的阻尼器可以与螺纹接合，以减缓螺纹穿过主体的后端的轴向运动，并且当透明区域与阻尼器平齐时，允许杆在体内的相对快速的轴向移动。