公开(公告)号：US10107739B2

公开(公告)日：2018-10-23

申请号：US15379546

申请日：2016-12-15

Applicant: UNCHAINED LABS

Inventor： Karsten Goede ,  Lothar Holz ,  Markus Lankers ,  Oliver K. Valet

IPC: G01N21/03 ,  G01N33/483 ,  G01N21/65

Abstract: Disclosed herein is a system, particularly a microscope system, for confocal Raman-spectroscopic measurements. The system is configured to detect minute sample amounts of microbes in a sample chamber with a lid, wherein the system is configured such that a comparably large working distance between the objective lens and the sample is sustained such that a measurement can be performed through the lid of the sample chamber. This allows for cultivating and measuring the sample in the same container.

公开(公告)号：US11209346B2

公开(公告)日：2021-12-28

申请号：US16603817

申请日：2018-04-11

Applicant: Unchained Labs

Inventor： Markus Lankers ,  Oliver Valet ,  Lisa Krapf ,  Karsten Goede ,  Steve Bober

IPC: G01J3/44 ,  G01N15/14 ,  G01N21/05 ,  G01N21/85 ,  G02B21/10 ,  G02B21/34 ,  G01N21/65 ,  G01N15/00

Abstract: The invention relates to a liquid cell (1) for the microscopic image capture and Raman spectroscopic material analysis of a particle suspension in a reflected light microscope, having at least the following components: a measuring chamber (2) which has a base (3), a measuring window (5) opposite the base (3), and a seal (6), wherein the base (3) has a planar design at least in one region of the support of the seal (6), and the base (3) has a reflective surface (4) which is provided such that Raman excitation light incident through the measuring window (5) is reflected on the reflective surface (4) in a directed manner such that the background signal in a Raman measurement is reduced and the Raman signal of a particle in a suspension is increased. The invention further relates to a microscope which has such a liquid cell.