公开(公告)号：US09642856B2

公开(公告)日：2017-05-09

申请号：US15029269

申请日：2014-10-03

Applicant: University Health Network

Inventor： David W. Hedley ,  Ines Lohse ,  Jacqueline M. Mason ,  Mark R. Bray

IPC: A61K31/5377 ,  A61K31/416 ,  A61P35/00 ,  C07D413/14 ,  A61K45/06 ,  A61K31/7068 ,  A61K33/24

CPC classification number: A61K31/5377 ,  A61K31/7068 ,  A61K33/24 ,  A61K45/06 ,  C07D403/08 ,  C07D413/14 ,  A61K2300/00

Abstract: The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof.

公开(公告)号：US20160250220A1

公开(公告)日：2016-09-01

申请号：US15029269

申请日：2014-10-03

Applicant: UNIVERSITY HEALTH NETWORK

Inventor： David W. Hedley ,  Ines Lohse ,  Jacqueline M. Mason ,  Mark R. Bray

IPC: A61K31/5377 ,  A61K33/24 ,  A61K31/7068

CPC classification number: A61K31/5377 ,  A61K31/7068 ,  A61K33/24 ,  A61K45/06 ,  C07D403/08 ,  C07D413/14 ,  A61K2300/00

Abstract: The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof.

Abstract translation: 本发明涉及通过施用结构式（I）表示的化合物或其药学上可接受的盐来治疗患有胰腺癌的受试者的方法。

公开(公告)号：US09555042B2

公开(公告)日：2017-01-31

申请号：US15029269

申请日：2014-10-03

Applicant: University Health Network

Inventor： David W. Hedley ,  Ines Lohse ,  Jacqueline M. Mason ,  Mark R. Bray

IPC: A61K31/5377 ,  A61K31/416 ,  A61P35/00 ,  C07D413/14 ,  A61K45/06 ,  A61K31/7068 ,  A61K33/24

Abstract: The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof.

Abstract translation: 本发明涉及通过施用结构式（I）表示的化合物或其药学上可接受的盐来治疗患有胰腺癌的受试者的方法。