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Patent Agency Ranking
公开(公告)号：US12264219B2
公开(公告)日：2025-04-01
申请号：US16634026
申请日：2018-07-27
Applicant: UNIVERSITY HEALTH NETWORK
Inventor： Ren-Ke Li
Abstract: The present disclosure relates to a biocompatible, electrically conductive biomaterial capable of carrying the electrical potential of a cardiac impulse. The biomaterial comprises a conductive polymer and a biocompatible component. The conductive polymer comprising an aminomethoxybenzoic acid (AMBA) polymer. The present disclosure also relates to treatments, uses and devices using the biocompatible, electrically conductive biomaterial.
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2.发明申请公开(公告)号：US20150366900A1
公开(公告)日：2015-12-24
申请号：US14765992
申请日：2014-02-04
Applicant: UNIVERSITY HEALTH NETWORK
Inventor： Ren-Ke Li
IPC: A61K31/787 , A61K47/48 , C08G61/12
CPC classification number: A61K31/787 , A61K9/0024 , A61K31/785 , A61K47/36 , A61K47/61 , A61K47/6435 , A61K47/6903 , A61L27/26 , A61L27/50 , A61L31/041 , A61L31/14 , A61L2400/06 , A61L2430/20 , C08G61/124 , C08G2261/128 , C08G2261/3221 , C08L89/06 , C08L5/08
Abstract: A biocompatible, electrically conductive biomaterial capable of earn carrying the electrical potential of a cardiac impulse and comprising (1) a conductive polymer such as polyaniline, polypyrrole or polythiophene, and (ii) a biocompatible component such as a polysaccharide, a protein, or a polypeptide, in particular chitosan or gelatin, is described. The material can take the form of a hydrogel, membrane, sheet or mesh. It can be used to restore or improve electrical impulse propagation across damaged tissue or scar region of the myocardium, in particular in the ti treatment of myocardial infarction and arrhythmia.
Abstract translation: 一种生物相容的导电生物材料，其能够产生携带心脏脉冲的电势，并且包括（1）导电聚合物，例如聚苯胺，聚吡咯或聚噻吩，和（ii）生物相容性组分如多糖，蛋白质或 多肽，特别是壳聚糖或明胶。 该材料可以采取水凝胶，膜，片或网的形式。 它可用于恢复或改善穿过受损组织或心肌瘢痕区域的电脉冲传播，特别是在心肌梗塞和心律失常的治疗中。
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公开(公告)号：US11052173B2
公开(公告)日：2021-07-06
申请号：US16419221
申请日：2019-05-22
Applicant: UNIVERSITY HEALTH NETWORK
Inventor： Ren-Ke Li
Abstract: The present disclosure relates to a biocompatible, electrically conductive polymer capable of carrying the electrical potential of a cardiac impulse. The present disclosure also relates to treatments using the electrically conductive polymer, such as for atrial fibrillation.
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公开(公告)号：US20210087336A1
公开(公告)日：2021-03-25
申请号：US16634026
申请日：2018-07-27
Applicant: UNIVERSITY HEALTH NETWORK
Inventor： Ren-Ke Li
Abstract: The present disclosure relates to a biocompatible, electrically conductive biomaterial capable of carrying the electrical potential of a cardiac impulse. The biomaterial comprises a conductive polymer and a biocompatible component. The conductive polymer comprising an aminomethoxybenzoic acid (AMBA) polymer. The present disclosure also relates to treatments, uses and devices using the biocompatible, electrically conductive biomaterial.
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公开(公告)号：US10350237B2
公开(公告)日：2019-07-16
申请号：US14765992
申请日：2014-02-04
Applicant: University Health Network
Inventor： Ren-Ke Li
IPC: A61K9/10 , A61K31/787 , A61K31/785 , A61L27/26 , A61L27/50 , A61L31/04 , A61L31/14 , C08G61/12 , A61K47/61 , A61K47/64 , A61K47/69 , A61K9/00 , A61K47/36
Abstract: A biocompatible, electrically conductive biomaterial capable of earn carrying the electrical potential of a cardiac impulse and comprising (1) a conductive polymer such as polyaniline, polypyrrole or polythiophene, and (ii) a biocompatible component such as a polysaccharide, a protein, or a polypeptide, in particular chitosan or gelatin, is described. The material can take the form of a hydrogel, membrane, sheet or mesh. It can be used to restore or improve electrical impulse propagation across damaged tissue or scar region of the myocardium, in particular in the ti treatment of myocardial infarction and arrhythmia.
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