公开(公告)号：US11746114B2

公开(公告)日：2023-09-05

申请号：US17665253

申请日：2022-02-04

Applicant: University of Windsor

Inventor： John Frederick Trant ,  Sarah Nasri ,  Maryamalsadat Kosar ,  Sanaz Nadimi ,  Mohaddeseh Dashti Nejad Pour ,  Purshotam Sharma ,  Seyedeh Maryamdokht Taimoory

IPC: C07D491/18 ,  C07K1/06

CPC classification number: C07D491/18 ,  C07K1/067

Abstract: In a preferred embodiment, there is provided a protecting group for protecting the thiol side chain of a cysteine residue, the protecting group comprising a Diels-Alder cycloadduct of a furan and a maleimide, and optionally, a linker interposed between the thiol side chain and the Diels-Alder cycloadduct.

公开(公告)号：US20220153749A1

公开(公告)日：2022-05-19

申请号：US17665253

申请日：2022-02-04

Applicant: University of Windsor

Inventor： John Frederick TRANT ,  Sarah Nasri ,  Maryamalsadat Kosar ,  Sanaz Nadimi ,  Mohaddeseh Dashti Nejad Pour ,  Purshotam Sharma ,  Seyedeh Maryamdokht Taimoory

IPC: C07D491/18 ,  C07K1/06

Abstract: In a preferred embodiment, there is provided a protecting group for protecting the thiol side chain of a cysteine residue, the protecting group comprising a Diels-Alder cycloadduct of a furan and a maleimide, and optionally, a linker interposed between the thiol side chain and the Diels-Alder cycloadduct.