公开(公告)号：US11666221B2

公开(公告)日：2023-06-06

申请号：US16613445

申请日：2018-05-18

Applicant: VANDERBILT UNIVERSITY

Inventor： Christine O'Brien ,  Katherine Cochran ,  Anita Mahadevan-Jansen ,  Kristen Rose Findley ,  William Stokes ,  Lowell Hays ,  Mohsin Tejani ,  Anne-Marie Crowe

IPC: G01J3/44 ,  A61B5/00 ,  G01J3/02 ,  G01J3/28

CPC classification number: A61B5/0075 ,  A61B5/435 ,  A61B5/6875 ,  G01J3/0248 ,  G01J3/2823

Abstract: A method for identification of biochemical markers associated with cervical remodeling over the course of pregnancy of humans includes obtaining Raman signals from the cervix of each of a group of humans with pregnancy at each phase of pregnancy; finding Raman signatures corresponding to each type of cervical tissue from the obtained Raman signals; and identifying biochemical markers associated with cervical remodeling at each phase of pregnancy corresponding to the Raman signatures.