IMAGING GUIDEWIRE WITH PHOTOACTIVATION CAPABILITIES
    1.
    发明申请
    IMAGING GUIDEWIRE WITH PHOTOACTIVATION CAPABILITIES 审中-公开
    具有摄影能力的成像指南

    公开(公告)号:US20140180056A1

    公开(公告)日:2014-06-26

    申请号:US14132479

    申请日:2013-12-18

    Inventor: Paul Hoseit

    Abstract: A guidewire providing imaging and light for photoactivation of therapeutic agents. Using optical fibers with Bragg gratings, electromagnetic waves are coupled to photoacoustic materials thereby providing acoustic energy for imaging tissues. The reflected acoustic waves can be sensed with photoreflective materials coupled to different optical fibers. Additional optical fibers allow photoactivated therapeutics to be activated in proximity to the imaged tissues. The photoactivated therapeutics may be administered intravenously or with a drug-delivery catheter.

    Abstract translation: 提供用于治疗剂的光活化的成像和光的导丝。 使用具有布拉格光栅的光纤,电磁波耦合到光声材料,从而为成像组织提供声能。 可以用耦合到不同光纤的光反射材料感测反射的声波。 另外的光纤使得光活化的治疗剂在被成像的组织附近被活化。 光活化治疗剂可以静脉内或与药物递送导管一起施用。

    Intravascular ultrasound imaging system with slip ring interface and associated devices, systems, and methods

    公开(公告)号:US10646200B2

    公开(公告)日:2020-05-12

    申请号:US14845093

    申请日:2015-09-03

    Abstract: An intravascular ultrasound (IVUS) imaging system is provided. The IVUS imaging system includes an intravascular device including a transducer shaft with an ultrasound transducer at a distal end. The IVUS imaging system also includes an interface module removably coupled to the intravascular device. The interface module includes a connector rotatably coupled to a proximal end of the transducer shaft; a motor coupled to the connector; a spinning element coupled to the motor, wherein the spinning element comprises four conductive rings; a stationary element comprising a plurality of brushes, wherein the stationary element is disposed proximate the spinning element such that a different one of the plurality of brushes is in mechanical contact with each of the four conductive rings; and four conductors coupled to the connector and the spinning element such that the stationary element and the intravascular device are in electrical communication.

    IMAGING AND REMOVING BIOLOGICAL MATERIAL
    3.
    发明申请
    IMAGING AND REMOVING BIOLOGICAL MATERIAL 审中-公开
    成像和去除生物材料

    公开(公告)号:US20140180316A1

    公开(公告)日:2014-06-26

    申请号:US14133066

    申请日:2013-12-18

    Inventor: Paul Hoseit

    Abstract: The invention generally relates to devices and methods for imaging and removing biological material from a vessel wall. In certain embodiments, the invention provides devices that include a body configured to fit within a lumen of a vessel, the body including an opening, a biological material removal assembly configured to remove biological material that is exposed to the removal assembly via the opening, and an imaging assembly coupled to the body and positioned to image the opening.

    Abstract translation: 本发明一般涉及用于从血管壁成像和去除生物材料的装置和方法。 在某些实施例中,本发明提供了一种装置,其包括构造成装配在容器内腔内的主体,该主体包括开口,生物材料去除组件,构造成移除通过开口暴露于移除组件的生物材料,以及 耦合到所述主体并被定位成对所述开口成像的成像组件。

    Imaging guidewire with photoactivation capabilities

    公开(公告)号:US10987492B2

    公开(公告)日:2021-04-27

    申请号:US14132479

    申请日:2013-12-18

    Inventor: Paul Hoseit

    Abstract: A guidewire providing imaging and light for photoactivation of therapeutic agents. Using optical fibers with Bragg gratings, electromagnetic waves are coupled to photoacoustic materials thereby providing acoustic energy for imaging tissues. The reflected acoustic waves can be sensed with photoreflective materials coupled to different optical fibers. Additional optical fibers allow photoactivated therapeutics to be activated in proximity to the imaged tissues. The photoactivated therapeutics may be administered intravenously or with a drug-delivery catheter.

    IMAGING CATHETER FOR IMAGING FROM WITHIN BALLOON
    6.
    发明申请
    IMAGING CATHETER FOR IMAGING FROM WITHIN BALLOON 审中-公开
    用于从气球成像的成像导管

    公开(公告)号:US20140180134A1

    公开(公告)日:2014-06-26

    申请号:US14108627

    申请日:2013-12-17

    Inventor: Paul Hoseit

    Abstract: The invention generally relates to balloon catheters for vascular intervention and particularly to devices for imaging from within a balloon. The invention provides a balloon catheter with an imaging device inside the balloon and capable of viewing a treatment site through a wall of the balloon. The device allows a physician to both view the affected site within the vessel and to inflate the balloon at the location that is in view, thus allowing the balloon to be deployed with good positioning and efficiency while minimizing a stiff length of the catheter to give it good maneuverability.

    Abstract translation: 本发明一般涉及用于血管干预的气囊导管,特别涉及用于从球囊内成像的装置。 本发明提供了一种气囊导管,其具有球囊内的成像装置并能够通过气囊的壁观察治疗部位。 该装置允许医生查看血管内的受影响位置并在视野中的气囊处使气囊膨胀,从而允许气囊以良好的定位和效率展开,同时最小化导管的刚度以给予它 良好的机动性。

    SYSTEM AND METHOD FOR FLUSH-TRIGGERED IMAGING
    7.
    发明申请
    SYSTEM AND METHOD FOR FLUSH-TRIGGERED IMAGING 审中-公开
    用于冲洗成像的系统和方法

    公开(公告)号:US20140180083A1

    公开(公告)日:2014-06-26

    申请号:US14109019

    申请日:2013-12-17

    Inventor: Paul Hoseit

    Abstract: The invention generally relates to intravascular imaging and methods of improved image quality by triggering image operations with a vessel flush. The invention provides systems and methods for intravascular imaging in which a flush such as the influx of clear saline or radiopaque dye triggers the imaging operation. The flush is detected by a mechanism—such as a pressure sensor or optical device on the imaging catheter, an external angiography system, or other device—that uses detection as a trigger to initiate imaging. Thus, when the blood is flushed, the catheter automatically takes a picture of the vessel wall.

    Abstract translation: 本发明一般涉及通过用血管冲洗来触发图像操作的血管内成像和改善图像质量的方法。 本发明提供了用于血管内成像的系统和方法,其中诸如清除盐水或不透射线染色剂的冲洗的冲洗触发成像操作。 冲洗通过诸如成像导管上的压力传感器或光学装置,外部血管造影系统或其他装置 - 使用检测作为触发来启动成像的机构来检测。 因此,当血液被冲洗时,导管自动拍摄血管壁。

    INTRAVASCULAR ULTRASOUND IMAGING SYSTEM WITH SLIP RING INTERFACE AND ASSOCIATED DEVICES, SYSTEMS, AND METHODS
    8.
    发明申请
    INTRAVASCULAR ULTRASOUND IMAGING SYSTEM WITH SLIP RING INTERFACE AND ASSOCIATED DEVICES, SYSTEMS, AND METHODS 审中-公开
    具有滑环接口和相关设备,系统和方法的血管内超声成像系统

    公开(公告)号:US20160066886A1

    公开(公告)日:2016-03-10

    申请号:US14845093

    申请日:2015-09-03

    CPC classification number: A61B8/4461 A61B8/0891 A61B8/12 A61B8/4411 A61B8/445

    Abstract: An intravascular ultrasound (IVUS) imaging system is provided. The IVUS imaging system includes an intravascular device including a transducer shaft with an ultrasound transducer at a distal end. The IVUS imaging system also includes an interface module removably coupled to the intravascular device. The interface module includes a connector rotatably coupled to a proximal end of the transducer shaft; a motor coupled to the connector; a spinning element coupled to the motor, wherein the spinning element comprises four conductive rings; a stationary element comprising a plurality of brushes, wherein the stationary element is disposed proximate the spinning element such that a different one of the plurality of brushes is in mechanical contact with each of the four conductive rings; and four conductors coupled to the connector and the spinning element such that the stationary element and the intravascular device are in electrical communication.

    Abstract translation: 提供血管内超声(IVUS)成像系统。 IVUS成像系统包括血管内装置,其包括在远端具有超声换能器的换能器轴。 IVUS成像系统还包括可移除地联接到血管内装置的接口模块。 接口模块包括可旋转地联接到换能器轴的近端的连接器; 耦合到所述连接器的马达; 联接到所述马达的旋转元件,其中所述旋转元件包括四个导电环; 包括多个电刷的固定元件,其中所述固定元件设置在所述旋转元件附近,使得所述多个电刷中的不同的电刷与所述四个导电环中的每一个机械接触; 以及连接到连接器和旋转元件的四个导体,使得静止元件和血管内装置电连通。

    IMAGING GUIDEWIRE WITH PRESSURE SENSING
    9.
    发明申请
    IMAGING GUIDEWIRE WITH PRESSURE SENSING 审中-公开
    带压力感应的成像指南

    公开(公告)号:US20140275950A1

    公开(公告)日:2014-09-18

    申请号:US14205726

    申请日:2014-03-12

    Inventor: Paul Hoseit

    Abstract: An intravascular element, for example a guidewire, configured for pressure measurements and imaging within a patient. In an embodiment, the invention uses a system of optical fibers and photoabsorptive and/or photoreflective materials to make intravascular ultrasound (IVUS) measurements. In an embodiment, the invention uses microfabricated pressure sensors to measure fluidic pressure adjacent to the element, such as the pressure of the blood within the vasculature. In a clinical setting, the invention can provide a surgeon with critical information about pressure, tissue composition, and luminal area while also reducing the time for procedures.

    Abstract translation: 血管内元件,例如导丝,被配置用于在患者体内进行压力测量和成像。 在一个实施例中,本发明使用光纤和光吸收和/或光反射材料的系统来进行血管内超声(IVUS)测量。 在一个实施例中,本发明使用微加压压力传感器来测量邻近元件的流体压力,例如脉管系统内血液的压力。 在临床环境中,本发明可以为外科医生提供关于压力,组织组成和腔面积的关键信息,同时也减少了手术的时间。

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