公开(公告)号：US20170356830A1

公开(公告)日：2017-12-14

申请号：US15541880

申请日：2015-10-19

Applicant: WASEDA UNIVERSITY

Inventor： Kiyotaka Iwasaki ,  Shumpei Saito

IPC: G01N3/02 ,  G01N3/08 ,  G01N33/483

CPC classification number: G01N3/02 ,  A61L27/00 ,  G01N3/04 ,  G01N3/08 ,  G01N33/4833

Abstract: A tensile testing machine exerts tensile force to biological, tissue attached to a bone. A fixture 10 according to the present invention includes a holder 11, which holds a bone B, and a support 12, which supports the holder 11. The holder 11 is provided with around-bone-axis angle adjusting mechanisms 14, 15, which adjust the angle of rotation of the bone B around the bone axis of the hone B held by the holder 11. The holder 11 and the support 12 are provided with bone inclination angle adjusting mechanisms 15, 34, which adjust the inclination angle of the bone B held by the holder 11. The support 12 is provided with lateral position adjusting mechanisms 34, 35, which adjust the lateral position of the holder 11 and longitudinal position adjusting mechanisms 35, 36, which adjust the longitudinal position of the holder 11.

公开(公告)号：US20210267467A1

公开(公告)日：2021-09-02

申请号：US17259988

申请日：2019-07-19

Applicant: WASEDA UNIVERSITY

Inventor： Masafumi Nakayama ,  Kiyotaka Iwasaki

IPC: A61B5/0215 ,  A61B5/026 ,  A61B5/349 ,  A61B5/00

Abstract: An ischemic cardiopathy diagnosis assistance system includes pressure data acquisition means 11 for acquiring pressure data including proximal pressure Pa in a proximal stenotic segment A1 and distal pressure Pd in a distal stenotic segment A2; intracoronary electrocardiogram data acquisition means 12 for acquiring intracoronary electrocardiogram data made up of a local intracoronary artery electrocardiogram in a neighborhood of the distal stenotic segment; and computational processing means 14 for finding a pressure ratio Pa/Pd between the proximal pressure Pa and distal pressure Pd at a time suitable for diagnosis of ischemic cardiopathy based on these data. The computational processing means temporally associates the pressure data with the intracoronary electrocardiogram data, estimates an analysis period T during which vascular resistance remains stably low from a waveform of the intracoronary electrocardiogram data, and extract the pressure data of the analysis period T, and finds the pressure ratio Pa/Pd from the pressure data.

公开(公告)号：US10660977B2

公开(公告)日：2020-05-26

申请号：US14389269

申请日：2013-04-01

Applicant: WASEDA UNIVERSITY

Inventor： Kiyotaka Iwasaki ,  Mitsuo Umezu

IPC: A61L2/00 ,  A61L27/36 ,  A01N1/02

Abstract: The present invention suppresses the strength reduction or degeneration of a tissue after the tissue is dried and/or sterilized, for the tissue comprising biological components and the like. Specifically, biological tissue is immersed in a trehalose solution and shaken, thereby impregnating the biological tissue with the trehalose solution. The trehalose solution used here is one obtained by dissolving trehalose in a phosphate buffered saline, the concentration of trehalose being preferably in the range of 20 wt % to 35 wt %. Thereafter, the biological tissue is dried to remove moisture in the biological tissue, and sterilized with ethylene oxide gas.

公开(公告)号：US20150064228A1

公开(公告)日：2015-03-05

申请号：US14389269

申请日：2013-04-01

Applicant: WASEDA UNIVERSITY

Inventor： Kiyotaka Iwasaki ,  Mitsuo Umezu

IPC: A61L2/00 ,  A61L27/36

CPC classification number: A61L2/0094 ,  A01N1/0221 ,  A01N1/0226 ,  A61L27/3687 ,  A61L2430/40

Abstract: The present invention suppresses the strength reduction or degeneration of a tissue after the tissue is dried and/or sterilized, for the tissue comprising biological components and the like. Specifically, biological tissue is immersed in a trehalose solution and shaken, thereby impregnating the biological tissue with the trehalose solution. The trehalose solution used here is one obtained by dissolving trehalose in a phosphate buffered saline, the concentration of trehalose being preferably in the range of 20 wt % to 35 wt %. Thereafter, the biological tissue is dried to remove moisture in the biological tissue, and sterilized with ethylene oxide gas.

Abstract translation: 本发明抑制组织干燥和/或灭菌后对于包含生物成分的组织等的组织的强度降低或变性。 具体地，将生物组织浸入海藻糖溶液中并摇动，从而用海藻糖溶液浸渍生物组织。 这里使用的海藻糖溶液是通过将海藻糖溶解在磷酸盐缓冲盐水中而获得的，海藻糖的浓度优选在20重量％〜35重量％的范围内。 此后，将生物组织干燥以除去生物组织中的水分，并用环氧乙烷气体灭菌。