公开(公告)号：US09766126B2

公开(公告)日：2017-09-19

申请号：US13941389

申请日：2013-07-12

Applicant: Zyomed Corp.

Inventor： Sandeep Gulati ,  Thomas George ,  Timothy L. Ruchti ,  Alan Abul-Haj ,  Kevin H. Hazen

IPC: A61B5/1455 ,  G01J3/42 ,  G01N21/47 ,  A61B5/00 ,  A61B5/107 ,  A61B5/145

CPC classification number: G01J3/42 ,  A61B5/0022 ,  A61B5/1079 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/14552 ,  A61B5/6801 ,  G01N21/474 ,  G01N2021/4742 ,  G01N2021/4747 ,  G01N2201/0826

Abstract: An analyzer apparatus and method of use thereof is described to dynamically irradiate a sample with incident light where the incident light is varied in time in terms of any of: position, radial position relative to a point of the skin of a subject, solid angle, incident angle, depth of focus, energy, and/or intensity. For example, the incident light is varied in radial position as a function of time relative to one or more of a sample site, a point on skin of the subject, a detection optic, and/or a sample volume observed by a detection system. The radially varied incident light is used to enhance and/or vary light probing the epidermis, the dermis, and/or the subcutaneous fat of the subject or of a group of subjects.

公开(公告)号：US09585604B2

公开(公告)日：2017-03-07

申请号：US14493283

申请日：2014-09-22

Applicant: Zyomed Corp.

Inventor： Timothy Ruchti ,  Alan Abul-Haj ,  Kevin Hazen

IPC: G01J5/02 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/1455 ,  A61B5/6801 ,  A61B2562/04 ,  A61B2562/046

Abstract: A noninvasive analyzer apparatus and method of use thereof is described comprising a near-infrared source, a detector, and a photon transport system configured to direct photons from the source to the detector via an analyzer-sample optical interface. The photon transport system includes a dynamically position light directing unit used to, within a measurement time period for a single analyte concentration determination, change any of: radius, energy, intensity, position, incident angle, solid angle, and/or depth of penetration of a beam of photons entering skin of a subject.

Abstract translation: 描述了一种非侵入性分析仪装置及其使用方法，其包括近红外源，检测器和光子传输系统，其被配置为经由分析仪样品光学界面将光子从源引导到检测器。 光子传输系统包括动态位置光导单元，用于在单个分析物浓度测定的测量时间段内改变以下任何一种：半径，能量，强度，位置，入射角，立体角和/或穿透深度 一束进入受试者皮肤的光子。