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    Cuvette assembly having chambers for containing samples to be evaluated through optical measurement
    2.
    发明授权
    Cuvette assembly having chambers for containing samples to be evaluated through optical measurement 审中-公开

    公开(公告)号：US10668466B2

    公开(公告)日：2020-06-02

    申请号：US16050105

    申请日：2018-07-31

    Applicant: BacterioScan LTD

    Inventor： Dana A. Marshall ,  Theodore S. McMinn ,  Dan Vadim Regelman

    IPC: B01L3/00 ,  G01N21/51

    Abstract: The present invention is a cuvette assembly for use in optically measuring at least one characteristic of particles within a plurality of liquid samples. The cuvette assembly comprises a main body having internal walls and external walls, and a plurality of cuvettes within the main body at least partially being defined by the internal walls. Each of the plurality of cuvettes has a liquid-input chamber for receiving a respective one of the plurality of liquid samples, a filter, and an optical chamber for receiving a respective filtered liquid sample caused by passing the respective one of the plurality of liquid samples through the filter. Each of the optical chambers includes an entry window for allowing transmission of an input light beam through the filtered liquid sample and an exit window for transmitting a forward scatter signal caused by the particles within the filtered liquid sample.

    Multi-sample laser-scatter measurement instrument with incubation feature and systems for using the same
    3.
    发明授权
    Multi-sample laser-scatter measurement instrument with incubation feature and systems for using the same 有权

    公开(公告)号：US10233481B2

    公开(公告)日：2019-03-19

    申请号：US14959054

    申请日：2015-12-04

    Applicant: BacterioScan LTD

    Inventor： Dana A. Marshall ,  Theodore S. McMinn ,  Dan Vadim Regelman

    IPC: C12Q1/06 ,  G01N33/487 ,  G01N21/51 ,  B01L3/00 ,  G01N21/25 ,  G01N21/47

    Abstract: An optical measurement instrument is an integrated instrument that includes an optical cavity with a light source, a sample cuvette, and an optical sensor. The light source and sensor are on a bench that is on a translational or rotational mechanical platform such that optical beam can be moved to multiple sample containers. The instrument can be used for taking measurements of organism concentration in multiple samples as a production tool for microbiology. Preferably, the instrument holds multiple, individually-loaded, independent fluid samples and determines bacteria concentration via a forward-scattering signal. The instrument can incorporate onboard incubation to promote bacterial growth in the samples during the test. In another aspect, the instrument can be a part of a network for medical diagnostic testing data where data is stored in a manner that is inherently untainted by patient identifiable information.

    Laser-scatter measurement instrument having carousel-based fluid sample arrangement
    4.
    发明授权
    Laser-scatter measurement instrument having carousel-based fluid sample arrangement 有权

    公开(公告)号：US10006857B2

    公开(公告)日：2018-06-26

    申请号：US15005321

    申请日：2016-01-25

    Applicant: BacterioScan LTD

    Inventor： Dana A. Marshall ,  Dan Vadim Regelman

    IPC: G01N21/51 ,  G01N21/03

    CPC classification number: G01N21/51 ,  G01N21/0303 ,  G01N2021/513 ,  G01N2201/0231 ,  G01N2201/0415

    Abstract: An instrument determines a concentration of bacteria in a plurality of fluid samples, and comprises a housing, a rotatable platform, a plurality of fluid containers, a light source, a sensor, and a motor. The rotatable platform is within the housing. The fluid containers are located on the rotatable platform. Each fluid container holds a corresponding one of the plurality of fluid samples, and has an input window and an output window. The light source provides an input beam for transmission into the input windows of the fluid containers and through the corresponding fluid samples. The input beam creates a forward-scatter signal associated with the concentration of bacteria. The motor rotates the rotatable platform so that the input beam sequentially passes through each fluid sample. A sensor within the housing detects the forward-scatter signal exiting from the output window associated with the fluid sample receiving the input beam.

    Cuvette assembly having chambers for containing samples to be evaluated through optical measurement
    5.
    发明授权
    Cuvette assembly having chambers for containing samples to be evaluated through optical measurement 有权
    比色杯组件，其具有用于容纳通过光学测量评价的样品的室

    公开(公告)号：US09579648B2

    公开(公告)日：2017-02-28

    申请号：US14562304

    申请日：2014-12-05

    Applicant: BacterioScan Inc.

    Inventor： Dana A. Marshall ,  Theodore S. McMinn ,  Dan Vadim Regelman

    IPC: B01L3/00 ,  G01N21/51

    CPC classification number: B01L3/50255 ,  B01L3/50853 ,  B01L2200/0684 ,  B01L2300/022 ,  B01L2300/043 ,  B01L2300/044 ,  B01L2300/045 ,  B01L2300/0654 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2400/0683 ,  G01N21/51 ,  G01N2021/513

    Abstract: The present invention is a cuvette assembly for use in optically measuring at least one characteristic of particles within a plurality of liquid samples. The cuvette assembly comprises a main body having internal walls and external walls, and a plurality of cuvettes within the main body at least partially being defined by the internal walls. Each of the plurality of cuvettes has a liquid-input chamber for receiving a respective one of the plurality of liquid samples, a filter, and an optical chamber for receiving a respective filtered liquid sample caused by passing the respective one of the plurality of liquid samples through the filter. Each of the optical chambers includes an entry window for allowing transmission of an input light beam through the filtered liquid sample and an exit window for transmitting a forward scatter signal caused by the particles within the filtered liquid sample.

    Abstract translation: 本发明是一种用于光学测量多个液体样品中的颗粒的至少一种特性的比色皿组件。 所述比色杯组件包括具有内壁和外壁的主体，并且所述主体内的多个比色皿至少部分地由所述内壁限定。 多个试管中的每一个具有用于接收多个液体样品中的相应一个液体样品的液体输入室，用于接收由多个液体样品中的相应一个液体样品引起的各自过滤液体样品的光学室 通过过滤器。 每个光学室包括入口窗口，用于允许输入光束通过过滤的液体样品和用于传输由过滤液体样品内的颗粒引起的前向散射信号的出射窗口。

    Pipette having integrated filtration assembly
    7.
    发明授权
    Pipette having integrated filtration assembly 有权

    公开(公告)号：US10065184B2

    公开(公告)日：2018-09-04

    申请号：US14978826

    申请日：2015-12-22

    Applicant: BacterioScan LTD

    Inventor： Dana A. Marshall ,  Robert W. Beckmann

    IPC: B01D27/10 ,  B01L3/02

    Abstract: The present invention is a pipette-filtration assembly having a main body defining a first channel, a second channel, a first valve, and a second valve. The first valve is associated with the first channel and permits flow in a first direction while substantially hindering flow in a second direction. The second valve is associated with the second channel and permits flow in the second direction while substantially hindering flow in the first direction. At least one filter is used to filter a fluid sample as the fluid sample flows in the first direction and/or the second direction. The pipette-filtration assembly is preferably disposable and includes one or two stages of integral filtration, primarily for use with an air-displacement pipetting or transfer system.

    Method and system for optical measurements of contained liquids having a free surface
    8.
    发明授权
    Method and system for optical measurements of contained liquids having a free surface 有权

    公开(公告)号：US10048198B2

    公开(公告)日：2018-08-14

    申请号：US14559286

    申请日：2014-12-03

    Applicant: BacterioScan Inc.

    Inventor： Dan Vadim Regelman

    IPC: G01N21/51 ,  E21B47/10 ,  G01N21/64 ,  G01N21/03

    Abstract: The present invention is an optical measurement system for measuring a liquid sample within a well. The system comprises a light source configured to transmit light though the well, a detector configured to measure optical signals derived from the transmitted light, and a tunable optical element. The tunable optical element is positioned between the light source and the well. The tunable optical element is operable to shape the light to compensate for distortions induced by a surface of the liquid sample. The detector is preferably located below the well for receiving a forward scatter signal indicative of at least one characteristic of the particles within the liquid sample.

    Cuvette assembly having chambers for containing samples to be evaluated through optical measurement
    10.
    发明授权
    Cuvette assembly having chambers for containing samples to be evaluated through optical measurement 有权

    公开(公告)号：US10040065B2

    公开(公告)日：2018-08-07

    申请号：US15425846

    申请日：2017-02-06

    Applicant: BacterioScan LTD.

    Inventor： Dana A. Marshall ,  Theodore S. McMinn ,  Dan Vadim Regelman

    IPC: B01L3/00 ,  G01N21/51

    Abstract: The present invention is a cuvette assembly for use in optically measuring at least one characteristic of particles within a plurality of liquid samples. The cuvette assembly comprises a main body having internal walls and external walls, and a plurality of cuvettes within the main body at least partially being defined by the internal walls. Each of the plurality of cuvettes has a liquid-input chamber for receiving a respective one of the plurality of liquid samples, a filter, and an optical chamber for receiving a respective filtered liquid sample caused by passing the respective one of the plurality of liquid samples through the filter. Each of the optical chambers includes an entry window for allowing transmission of an input light beam through the filtered liquid sample and an exit window for transmitting a forward scatter signal caused by the particles within the filtered liquid sample.

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