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    Substrates and associated methods for elution of nucleic acids
    9.
    发明授权
    Substrates and associated methods for elution of nucleic acids 有权
    底物和相关的核酸洗脱方法

    公开(公告)号：US09534214B2

    公开(公告)日：2017-01-03

    申请号：US14068633

    申请日：2013-10-31

    Applicant: General Electric Company

    Inventor： Bing Li ,  Gregory Andrew Grossmann ,  Erik Leeming Kvam ,  Brian Christopher Bales ,  Jason Louis Davis

    IPC: C12N15/10 ,  B01J20/22 ,  B01J20/26

    CPC classification number: C12N15/1006 ,  B01J20/22 ,  B01J20/261 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3248 ,  B01J20/3251 ,  B01J20/3255 ,  B01J20/3274 ,  C12N15/1017

    Abstract: A solid substrate for biological sample storage under dry-state and elution of biomolecules is provided. The dry, solid substrate is coated with saccharides, such as monosaccharides, oligosaccharides, polysaccharides or combinations thereof, and the substrate is comprised of one or more protein denaturing agents impregnated therein under a substantially dry state. A method for elution of biomolecules from biological samples is also provided. The compositions disclosed herein provide for enhanced elution and recovery of biomolecules, such as nucleic acids, from the sample. The sample is disposed on a substrate, dried to a substantially dry state; eluted from the biological sample dried on the substrate by rehydrating the substrate in an elution buffer.

    Abstract translation: 提供了一种在干态下生物样品储存和生物分子洗脱的固体底物。 干燥的固体底物涂覆有糖，例如单糖，寡糖，多糖或其组合，并且底物由一种或多种在基本干燥状态下浸渍的蛋白质变性剂组成。 还提供了用于从生物样品中洗脱生物分子的方法。 本文公开的组合物提供来自样品的生物分子（例如核酸）的增强的洗脱和回收。 将样品置于基材上，干燥至基本干燥状态; 通过在洗脱缓冲液中再水化底物，从在底物上干燥的生物样品中洗脱。

    USE OF AN ORGANIC-INORGANIC HYBRID MATERIAL FOR EXTRACTING URANIUM(VI) FROM A SULFURIC ACID AQUEOUS SOLUTION, ISSUED NOTABLY FROM THE SULFURIC LEACHING OF A URANIUM-BEARING ORE
    10.
    发明申请
    USE OF AN ORGANIC-INORGANIC HYBRID MATERIAL FOR EXTRACTING URANIUM(VI) FROM A SULFURIC ACID AQUEOUS SOLUTION, ISSUED NOTABLY FROM THE SULFURIC LEACHING OF A URANIUM-BEARING ORE 有权
    使用有机无机混合材料从硫酸水溶液中提取铀（Ⅵ），不可避免地来自铀轴承的硫浸渍

    公开(公告)号：US20160289796A1

    公开(公告)日：2016-10-06

    申请号：US15034779

    申请日：2014-11-06

    Applicant: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES

    Inventor： Agnès GRANDJEAN ,  Frédéric CUER

    IPC: C22B60/02 ,  B01J20/22 ,  B01J20/28 ,  C22B3/42

    CPC classification number: C22B60/0234 ,  B01J20/22 ,  B01J20/28083 ,  B01J20/3204 ,  B01J20/3251 ,  B01J20/3259 ,  C22B3/42 ,  C22B60/0252 ,  Y02P10/234

    Abstract: The invention relates to the use of an organic-inorganic hybrid material, comprising an inorganic solid support on which are grafted organic molecules having the general formula (I) below: in which: x, y and z=0 or 1, with at least one of x, y and z different from 0; m=1 to 6; v and w=0 or 1, with v=1 when w=0, and v=0 when w=1; if x=0, R1═H or a saturated or unsaturated, linear or branched, C1 to C12 hydrocarbon group, whereas, if x=1, R1=a group bound to the inorganic solid support by at least one covalent bond; if y=0, R2═H or a saturated or unsaturated, linear or branched, C1 to C12 hydrocarbon group, whereas, if y=1, R2=a group bound to the inorganic solid support by at least one covalent bond; if z=0, R3═H or a saturated or unsaturated, linear or branched, C1 to C12 hydrocarbon group, whereas, if z=1, R3=a group bound to the inorganic solid support by at least one covalent bond; R4 and R5═H, a saturated or unsaturated, linear or branched, C2 to C8 hydrocarbon group, or a monocyclic aromatic group; for extracting uranium(VI) from a sulfuric acid aqueous solution. The invention also relates to a method that makes it possible to recover the uranium(VI) present in a sulfuric acid aqueous solution, selectively with respect to the other metal cations that may also be present in said solution.

    Abstract translation: 本发明还涉及一种可以相对于也可能存在于所述溶液中的其它金属阳离子选择性地回收存在于硫酸水溶液中的铀（VI）的方法。

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