-
公开(公告)号：WO2018005770A2
公开(公告)日：2018-01-04
申请号：PCT/US2017/039954
申请日：2017-06-29
Applicant: INVISTA NORTH AMERICA S.Á.R.L.
Inventor： CHOKKATHUKALAM, Achuthanunni , CONRADIE, Alex Van Eck , HADDOUCHE, Ramdane , SURAE, Satnam , TIBBLES, Katherine Louise
CPC classification number: C12N15/52 , C12N9/0006 , C12N9/0008 , C12N9/001 , C12N9/1025 , C12N9/1029 , C12N9/13 , C12N9/88 , C12N9/90 , C12N9/93 , C12P7/40 , C12Y101/01027 , C12Y101/99007 , C12Y102/01002 , C12Y102/0101 , C12Y102/01043 , C12Y103/01084 , C12Y203/01054 , C12Y203/03005 , C12Y208/03 , C12Y401/01031 , C12Y403/01006 , C12Y403/01019 , C12Y404/01001 , C12Y503/01027 , C12Y602/01036 , Y02P20/134
Abstract: The present disclosure relates to methods for more efficiently recycling reduced electron carriers in a hydrogen-oxidizing microorganism with an operable Calvin-Benson cycle; synthetic carbon fixation pathways that recycle reduced electron carriers more efficiently than the Calvin-Benson cycle, such as methods for enzymatically converting carbon dioxide to formate and assimilating the resulting formate into central carbon metabolism; methods for producing biochemical products; and recombinant hosts utilizing one or more synthetic carbon fixation pathways.
Abstract translation: 本公开涉及用可操作的卡尔文 - 本森循环更有效地再循环氢氧化微生物中的还原电子载体的方法; 比Calvin-Benson循环更有效地循环还原电子载体的合成碳固定途径，例如将二氧化碳酶促转化为甲酸并将所得甲酸同化为中心碳代谢的方法; 生产生化产品的方法; 和利用一种或多种合成碳固定途径的重组宿主。
-
2.发明申请
公开(公告)号：WO2016085811A1
公开(公告)日：2016-06-02
申请号：PCT/US2015/061861
申请日：2015-11-20
Applicant: INVISTA NORTH AMERICA S.Á.R.L.
Inventor： BOTES, Adriana Leonora , CONRADIE, Alex Van Eck , HADDOUCHE, Ramdane
CPC classification number: C12P7/6409 , C07C47/12 , C07C47/19 , C07C55/16 , C07C59/01 , C07C225/06 , C07C229/08 , C07C233/31 , C12N9/0006 , C12N9/0008 , C12N9/0071 , C12N9/0073 , C12N9/16 , C12N9/18 , C12P7/42 , C12P13/001 , C12P13/005 , C12Y114/14001 , C12Y206/01 , C12Y301/01003
Abstract: This document describes biochemical pathways for producing 7-hydroxyheptanoic acid using a polypeptide having monooxygenase activity to form a 8-hydroxynonanoate intermediate, which can be converted to 7-hydroxyheptanoate using a polypeptide having monooxygenase activity, a polypeptide having secondary alcohol dehydrogenase activity, and a polypeptide having esterase activity. 7-hydroxyheptanoic acid can be enzymatically converted to pimelic acid, 7-aminoheptanoic acid, heptamethylenediamine or 1,7 heptanediol. This document also describes recombinant hosts producing 7-hydroxyheptanoic acid as well as pimelic acid, 7-aminoheptanoic acid, heptamethylenediamine and 1,7 heptanediol.
Abstract translation: 本文件描述了使用具有单加氧酶活性的多肽形成8-羟基壬酸酯中间体以产生7-羟基庚酸的生物化学途径，其可以使用具有单加氧酶活性的多肽，具有仲醇脱氢酶活性的多肽转化为7-羟基庚酸酯， 具有酯酶活性的多肽。 7-羟基庚酸可以酶促转化成庚二酸，7-氨基庚酸，七亚甲基二胺或1,7庚二醇。 该文献还描述了产生7-羟基庚酸以及庚二酸，7-氨基庚酸，七亚甲基二胺和1,7庚二醇的重组宿主。
-
公开(公告)号：WO2018005770A8
公开(公告)日：2018-01-04
申请号：PCT/US2017/039954
申请日：2017-06-29
Applicant: INVISTA NORTH AMERICA S.Á.R.L.
Inventor： CHOKKATHUKALAM, Achuthanunni , CONRADIE, Alex Van Eck , HADDOUCHE, Ramdane , SURAE, Satnam , TIBBLES, Katherine Louise
Abstract: The present disclosure relates to methods for more efficiently recycling reduced electron carriers in a hydrogen-oxidizing microorganism with an operable Calvin-Benson cycle; synthetic carbon fixation pathways that recycle reduced electron carriers more efficiently than the Calvin-Benson cycle, such as methods for enzymatically converting carbon dioxide to formate and assimilating the resulting formate into central carbon metabolism; methods for producing biochemical products; and recombinant hosts utilizing one or more synthetic carbon fixation pathways.
-
公开(公告)号：WO2018005770A3
公开(公告)日：2018-01-04
申请号：PCT/US2017/039954
申请日：2017-06-29
Applicant: INVISTA NORTH AMERICA S.Á.R.L.
Inventor： CHOKKATHUKALAM, Achuthanunni , CONRADIE, Alex Van Eck , HADDOUCHE, Ramdane , SURAE, Satnam , TIBBLES, Katherine Louise
Abstract: The present disclosure relates to methods for more efficiently recycling reduced electron carriers in a hydrogen-oxidizing microorganism with an operable Calvin-Benson cycle; synthetic carbon fixation pathways that recycle reduced electron carriers more efficiently than the Calvin-Benson cycle, such as methods for enzymatically converting carbon dioxide to formate and assimilating the resulting formate into central carbon metabolism; methods for producing biochemical products; and recombinant hosts utilizing one or more synthetic carbon fixation pathways.
-
-
-
Search Results
4
records
(took 0.011 seconds)
