Invention Grant
- Patent Title: Method for expansion of double negative regulatory T cells
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Application No.: US15573379Application Date: 2016-05-11
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Publication No.: US11534460B2Publication Date: 2022-12-27
- Inventor: Li Zhang , Paulina Achita , Jong Lee , Dalam Ly , Dzana Dervovic
- Applicant: UNIVERSITY HEALTH NETWORK
- Applicant Address: CA Toronto
- Assignee: UNIVERSITY HEALTH NETWORK
- Current Assignee: UNIVERSITY HEALTH NETWORK
- Current Assignee Address: CA Toronto
- Agency: Norton Rose Fulbright US LLP
- International Application: PCT/CA2016/000136 WO 20160511
- International Announcement: WO2016/179684 WO 20161117
- Main IPC: A61K35/17
- IPC: A61K35/17 ; C12N5/0783 ; A61P35/00
Abstract:
There is provided herein a method for expanding human CD4-CD8- regulatory T cells (DN Tregs) from a population of cells comprising DN Tregs, comprising: culturing the population of cells with artificial antigen presenting cells (APCs), preferably the DN Tregs are αβ-TCR-CD56- or alternatively γ8-TCR+.
Public/Granted literature
- US20180104278A1 METHOD FOR EXPANSION OF DOUBLE NEGATIVE REGULATORY T CELLS Public/Granted day:2018-04-19
Information query
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