Abstract:
PURPOSE: A retrospective cohort research based drug side effect clue sensing method using an electronic medical record is provided to increase accuracy of a result according to accumulation of an electronic medical record database and supply various statistical results, thereby helping additional determination of a user. CONSTITUTION: A drug which would find side effect and an inspection which would find a side effect clue are determined(S100). A drug exposure candidate and a drug non-exposure candidate are extracted from an electronic medical record database(S150). A drug exposure group and a drug non-exposure group are selected by matching the drug exposure candidate and the drug non-exposure candidate with an important variable. A drug injection representation value among an inspection result of drug exposure group patients and a drug non-injection representation value among the inspection result of drug non-exposure group patients are determined(S500). The side effect of the drug is determined through statistics verification of the drug injection representation value and the drug non-injection representation value(S600). [Reference numerals] (AA) Start; (BB) End; (S100) Determining a drug and a test to detect side effects; (S150) Extracting drug exposure and non-exposure candidate groups; (S200) Selecting a side effect examinee group; (S250) Selecting a group of examinees without side effects to an initial test; (S300) Matching drug exposure and non-exposure candidate groups; (S500) Determining an after-drug-injection representative value(PostLab) and a non-drug-injection representative value(NoLab); (S600) Comparing the PostLab and NoLab and determining the occurrence of side effects; (S700) Coding "0" or "1" according to the occurrence of side effects; (S800) Statistical analysis such as conditional logistic regression analysis; (S900) Determining side effects of the drug
Abstract:
PURPOSE: A method for sensing a side effect of drug and surgery by using a computerized patient record and electrocardiogram data is provided to multiply accuracy of a result by accumulating EMR database and to rapidly sense various side effects about the drug and surgery. CONSTITUTION: A patient which takes drug is selected(S100). An initial time point when the drug is put into the patient is identified(S200). The patient performing electrocardiography before and after the initial time point is extracted(S300). A representative value before drug administration and a representative value after the drug administration among results of the electrocardiography of the extracted patient are determined(S400). Whether the drug causes a side effect or not is determined(S500).
Abstract:
본 발명은 하나의 샘플 내의 개별적인 상호 작용이 있는 유전자 (또는 단백질) 쌍의 합동-발현 스코어(co-expressed score)에 기반을 두고 차등 합동-발현 유전자 쌍(differentially co-expressed interacting gene pairs, DEPs)을 이용함으로써, HIV-1 감염의 단계-특이적인 유전자 특징을 구별하며 그로 인해 HIV TYPE 1 감염 단계를 보다 명확하게 구별할 수 있는 방법에 관한 것이다.
Abstract:
PURPOSE: A drug or surgical operation side effect detecting method based on a patient-control group is provided to accurately inspect various side effects by grasping objective statistics. CONSTITUTION: A drug for inspecting a side effect is determined(S100). A candidate of a case group and a control group candidate are extracted from an EMR(Electronic Medical Record) database(S150). An inclination score of a patients is calculated(S200). A control group is classified from the control group candidate(S300). A representative value(PostQT) after giving a drug and a representative value(NoQT) after non-putting the drug are determined(S500). Whether the drug has the side effect or not is determined(600).