Abstract:
본발명은산사자의에틸아세테이트분획물또는 n-부탄올분획물을포함하는염증성질환의예방또는치료용조성물에관한것으로, 상기분획물은대식세포에서의 IL-6 및 NO 생성을저해하는활성및 인간각질형성세포에서의 IP-10, Rantes 및 MDC 생성을저해하는활성이우수하여염증성질환의예방또는치료용조성물, 또는, 염증성질환의예방또는개선용건강기능식품, 또는, 피부염증의예방또는개선용화장료조성물로유용하게사용될수 있다.
Abstract:
The present invention relates to novel Paenibacillussp. MBT213 (microorganism deposition number KACC91831P) and to a fermented ginseng using the same. In addition, the present invention relates to a composition for preventing or treating atopic dermatitis which comprises extracts of fermented ginseng using Paenibacillussp. MBT213. A culture media of the Paenibacillussp. MBT213 (microorganism deposition number KACC91831P) has excellent effects which converts ginsenoside Rg1 inside the ginseng into Rd. In addition, the fermented ginseng or extract of the same which is manufactured by using the effects suppresses activities of MIP-1α (macrophage inflammatory protein-1α), IL-4 (interleukin-4) and IL-13 (interleukin-13) in order to be used as a medicine for treating or alleviating symptoms of various skin diseases such as atopic dermatitis.