公开(公告)号：US20190046419A1

公开(公告)日：2019-02-14

申请号：US16078069

申请日：2017-02-16

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Kai U. Claussen ,  Johannes M. Leykauff ,  Christine Lienau ,  Reinhold Hecht ,  Peter Braun ,  Markus Mikulla

IPC: A61K6/06 ,  A61K6/083 ,  A61K6/097 ,  A61C5/00 ,  A61C5/50

Abstract: The invention relates to a kit of parts for preparing a glass ionomer composition for dental use, the kit comprising a Paste A and a Paste B, Paste A comprising water, acid-reactive inorganic filler A, phyllo silicate(s), Paste B comprising water, poly-acid, non acid-reactive filler B, optionally chelating agent. The invention also relates to a hardenable composition obtainable by combining the pastes of the kit or parts and to the use of such a composition as or for preparing a dental cement, dental filling mater ial, dental core build up material or dental root channel filling material.

公开(公告)号：US20170056298A1

公开(公告)日：2017-03-02

申请号：US15119241

申请日：2015-02-18

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Adrian S. Eckert ,  Michael Cub ,  Bettina Hailand ,  Marion B. Kestel ,  Christoph Thalacker ,  Karsten Dede ,  Uwe H. Hoheisel ,  Reinhold Hecht ,  Henry Loll ,  Bernhard Hofmann

IPC: A61K6/083 ,  A61K6/00

CPC classification number: A61K6/083 ,  A61K6/005 ,  A61K6/0052 ,  A61K6/0073 ,  A61K6/0088 ,  A61K6/0091 ,  C08L33/10 ,  C08L33/08

Abstract: The invention relates to a dental composition comprising polymerizable monomer (1), initiator component(s), filler component(s) in an amount of more than about 20 wt.-%, wt.-% with respect to the whole weight of the composition, the polymerizable monomer (1) being characterized as follows: having exactly two (meth)acrylate reactive moieties, having an unsymmetrical backbone as linkage between the (meth)acrylate reactive moieties, the two (meth)acrylate reactive moieties being attached onto the unsymmetrical monomer backbone as alkyl esters, the unsymmetrical backbone comprising one aromatic moiety of the phenolic type, the polymerizable monomer (1) not containing an acidic moiety, other atoms than carbon, hydrogen, and oxygen, bisphenol moieties. The invention also relates to the use of the dental composition as or for producing a dental filling material, crown and bridge material, inlay, onlay, veneer or dental mill blank.

Abstract translation: 本发明涉及一种牙科用组合物，其包含可聚合单体（1），引发剂组分，多于约20重量％，重量％的填料组分，相对于 组合物，可聚合单体（1）的特征如下：具有正好两个（甲基）丙烯酸酯反应性部分，在（甲基）丙烯酸酯反应性部分之间具有不对称主链作为连接，两个（甲基）丙烯酸酯反应性部分连接到 不对称单体主链作为烷基酯，不对称主链包含一个酚类芳族部分，不含酸性部分的可聚合单体（1），其它原子比碳，氢和氧，双酚部分。 本发明还涉及将牙科用组合物用于或用于制造牙科填充材料，冠和桥材料，镶嵌，镶嵌，单板或牙磨机坯料的用途。

公开(公告)号：US20140329205A1

公开(公告)日：2014-11-06

申请号：US14360373

申请日：2012-11-30

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Reinhold Hecht ,  Andrea Stippschild ,  Vitore Hasanaj ,  Gioacchino Raia ,  Manfred Ludsteck ,  Rainer Guggenberger

IPC: A61K6/083 ,  A61C13/15

CPC classification number: A61K6/083 ,  A61C19/003 ,  C09J133/10 ,  C09J133/14 ,  C09J175/16 ,  C08L33/00 ,  C08L43/02

Abstract: The invention relates to a one-component self-adhesive composition for dental use comprising radically polymerizable component(s) with an acidic moiety as component A, radically polymerizable component(s) without an acidic moiety as component (B), an oxidizing agent comprising persulfate(s) as component (C), transition metal component(s) as component (D), photoinitiator system(s) as component (E), optionally non acid-reactive filler(s) as component (F), and optionally additive(s) as component (G).

Abstract translation: 本发明涉及一种用于牙科用途的单组分自粘组合物，其包含具有酸性部分作为组分A的可自由基聚合的组分，不具有作为组分（B）的酸性部分的可自由基聚合的组分，包含 作为组分（C）的过硫酸盐，作为组分（D）的过渡金属组分，作为组分（E）的光引发剂体系，作为组分（F）的任选的非酸反应性填料，以及任选的 添加剂作为组分（G）。

公开(公告)号：US20200368117A1

公开(公告)日：2020-11-26

申请号：US16967937

申请日：2019-02-01

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Kai U. Claussen ,  Silke D. Mechernich ,  Mareike Richter ,  Reinhold Hecht ,  Manfred Ludsteck ,  Simone Jurjevic

IPC: A61K6/889 ,  A61C5/00 ,  A61C7/00 ,  A61K6/17 ,  C08F222/10

Abstract: The invention relates to a microcapsule comprising a hollow or porous core, the hollow or porous core being composed of a polymeric material and containing a component of a redox-initiator system, a shell, the shell being composed of a pH-sensitive material. The microcapsule can be used for formulating dental materials.

公开(公告)号：US09782329B2

公开(公告)日：2017-10-10

申请号：US14902948

申请日：2014-07-01

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Reinhold Hecht ,  Uwe H. Hoheisel ,  Adrian S. Eckert ,  Bernhard Hofmann

IPC: A61K6/083 ,  A61K6/00 ,  A61K6/09

CPC classification number: A61K6/083 ,  A61K6/0008 ,  A61K6/0073 ,  A61K6/0088 ,  A61K6/09 ,  C08L33/14 ,  C08L75/16

Abstract: The invention relates to a dental composition comprising filler (F1) comprising aggregated nano-sized particles in an amount of from about 30 to about 70 wt. %, filler (F2) comprising agglomerated nano-sized particles in an amount from about 1 to about 20 wt. %, hardenable component (A1) being an urethane(meth)acrylate with a functionality of at least 2 and having a molecular weight from about 400 to about 3,000 g/mol,-hardenable component (A2) being a radically polymerizable (meth)acrylate with a functionality of at least 2 being different from component (A1), redox curing initiator system, the dental composition not comprising non-agglomerated nano-sized filler in an amount above about 10 wt. %, wt. % with respect to the weight of the whole composition. The dental composition is in particular useful as or for production of permanent crown and bridges, inlays, onlays and veneers.

公开(公告)号：US20170065495A1

公开(公告)日：2017-03-09

申请号：US15119172

申请日：2015-02-18

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Adrian S. Eckert ,  Michael Cub ,  Bettina Hailand ,  Ines Edelmann ,  Christoph Thalacker ,  Karsten Dede ,  Uwe H. Hoheisel ,  Reinhold Hecht

IPC: A61K6/00

CPC classification number: A61K6/0023 ,  A61K6/0052 ,  A61K6/0088 ,  C08L33/10 ,  C08L33/08

Abstract: An adhesive dental composition comprising a polymerizable monomer (1), a polymerizable monomer (2) comprising an acidic moiety, initiator component(s), filler component(s) in an amount of less than about 15 wt.-%, wt.-% with respect to the whole weight of the composition, the polymerizable monomer (1) being characterized as follows: having exactly two (meth)acrylate reactive moieties, having an unsymmetrical backbone as linkage between the (meth)acrylate reactive moieties, the two (meth)acrylate reactive moieties being attached onto the unsymmetrical monomer backbone as alkyl esters, the unsymmetrical backbone comprising one aromatic moiety of the phenolic type, the polymerizable monomer (1) not containing an acidic moiety, other atoms than carbon, hydrogen, and oxygen, bisphenol moieties. The invention also relates to the use of the adhesive dental composition as dental adhesive, sealant, cement or for bonding or cementing a material to the surface of hard dental tissue.

Abstract translation: 一种粘合剂牙科用组合物，其包含可聚合单体（1），包含酸性部分的可聚合单体（2），引发剂组分，少于约15重量％的量的填料组分， 相对于组合物的整个重量，可聚合单体（1）的特征如下：具有正好两个（甲基）丙烯酸酯反应性部分，在（甲基）丙烯酸酯反应性部分之间具有不对称主链作为连接， 甲基）丙烯酸酯反应性部分作为烷基酯连接到非对称单体骨架上，不对称骨架包含一种酚类芳族部分，不含酸性部分的可聚合单体（1），除碳，氢和氧以外的其它原子， 双酚部分。 本发明还涉及粘合剂牙科组合物作为牙科粘合剂，密封剂，水泥或用于将材料粘结或粘合到硬牙齿组织表面上的用途。

公开(公告)号：US20160136059A1

公开(公告)日：2016-05-19

申请号：US14902948

申请日：2014-07-01

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Reinhold Hecht ,  Uwe H. Hoheisel ,  Adrian S. Eckert ,  Bernhard Hofmann

IPC: A61K6/083 ,  A61K6/00

CPC classification number: A61K6/083 ,  A61K6/0008 ,  A61K6/0073 ,  A61K6/0088 ,  A61K6/09 ,  C08L33/14 ,  C08L75/16

Abstract: The invention relates to a dental composition comprising—filler (F1) comprising aggregated nano-sized particles in an amount of from about 30 to about 70 wt. %, —filler (F2) comprising agglomerated nano-sized particles in an amount from about 1 to about 20 wt. %, —hardenable component (A1) being an urethane(meth)acrylate with a functionality of at least 2 and having a molecular weight from about 400 to about 3,000 g/mol, —hardenable component (A2) being a radically polymerizable (meth)acrylate with a functionality of at least 2 being different from component (A1), —redox curing initiator system, the dental composition not comprising non-agglomerated nano-sized filler in an amount above about 10 wt. %, wt. % with respect to the weight of the whole composition. The dental composition is in particular useful as or for production of permanent crown and bridges, inlays, onlays and veneers.

Abstract translation: 本发明涉及包含填充物（F1）的牙科用组合物，其包含约30至约70重量％的聚集的纳米尺寸颗粒。 ％， - 填料（F2），其包含约1至约20重量％的聚集的纳米尺寸颗粒。 ％的可硬化组分（A1）是官能度为至少为2且分子量为约400至约3,000g / mol的聚氨酯（甲基）丙烯酸酯，可硬化组分（A2）为可自由基聚合的（甲基） 具有至少2个官能度的丙烯酸酯与组分（A1），-redox固化引发剂体系不同，所述牙科用组合物不包含高于约10重量％的非团聚纳米尺寸填料。 ％，wt。 相对于整个组合物的重量。 牙科用组合物特别用作永久性冠和桥，镶嵌，镶嵌和单板的生产。

公开(公告)号：US20240245585A1

公开(公告)日：2024-07-25

申请号：US18574390

申请日：2022-06-01

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Bernhard C. Hofmann ,  Reinhold Hecht ,  Wolf Steiger ,  Peter Bissinger

IPC: A61K6/887 ,  A61K6/62 ,  A61K6/71 ,  A61K6/76 ,  A61K6/77 ,  A61K6/79 ,  A61K6/893 ,  C04B26/06 ,  C04B111/00

CPC classification number: A61K6/887 ,  A61K6/62 ,  A61K6/71 ,  A61K6/76 ,  A61K6/77 ,  A61K6/79 ,  A61K6/893 ,  C04B26/06 ,  C04B2111/00836

Abstract: The invention relates to a dental cement composition comprising a resin matrix comprising a (meth)acrylate component comprising at least two (meth)acrylate moieties, a polyol spacer group between the at least two (meth)acrylate moieties, the polyols spacer group having a molecular weight Mw of at least 3,000 g/mol, an acidic polymerizable component, preferably an acidic (meth)acrylate component, a non-acidic polymerizable component having a molecular weight Mw below 1,000 g/mol, preferably a non-acidic (meth)acrylate component, filler, an initiator system, optionally additives. The invention also relates to a kit of parts comprising the dental cement composition, a dental crown or a curable dental composition for producing a temporary dental restoration being different from the dental cement composition. The dental cement composition is intended for use in a process of temporarily restoring a dental situation in a mouth of a patient.

公开(公告)号：US20230320942A1

公开(公告)日：2023-10-12

申请号：US18333956

申请日：2023-06-13

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Andreas HERRMANN ,  Gioacchino Raia ,  Malte Korten ,  Oliver Kappler ,  Bernhard Hofmann ,  Adrian Eckert ,  Helmar Mayr ,  Reinhold Hecht ,  Gallus Schechner ,  Rainer Guggenberger

IPC: A61K6/887 ,  A61C5/73 ,  A61K6/77 ,  A61K6/65 ,  A61K6/76 ,  A61K6/62 ,  A61K6/17 ,  C08L33/08 ,  C08L33/10 ,  C08L75/06

CPC classification number: A61K6/887 ,  A61C5/73 ,  A61K6/77 ,  A61K6/65 ,  A61K6/76 ,  A61K6/62 ,  A61K6/17 ,  C08L33/08 ,  C08L33/10 ,  C08L75/06

Abstract: The invention relates to A curable composition for producing dental composite crowns, the composition comprising a resin matrix comprising polymerizable (meth)acrylate(s) not comprising a urethane moiety, polymerizable urethane(meth)acrylate(s), wherein the polymerizable (meth)acrylate(s) not comprising an urethane moiety are used in excess over the polymerizable urethane(meth)acrylate(s), a filler matrix comprising nanocluster(s), fumed silica in an amount below 8 wt. % with respect to the weight of the whole composition, an initiator system comprising photoinitiator(s), organic dye(s), the curable composition not comprising softener in an amount of more than 5 wt. % with respect to the weight of the whole composition, the curable composition having a viscosity below 150 Pa*s at 23° C. and a shear rate of 1 s−1.
The invention also relates to a cured article obtained by radiation curing this curable composition by use of an additive-manufacturing method.

公开(公告)号：US11696875B2

公开(公告)日：2023-07-11

申请号：US16622530

申请日：2018-06-05

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Andreas Herrmann ,  Gioacchino Raia ,  Malte Korten ,  Oliver Kappler ,  Bernhard Hofmann ,  Adrian Eckert ,  Helmar Mayr ,  Reinhold Hecht ,  Gallus Schechner ,  Rainer Guggenberger

IPC: A61K6/887 ,  A61C5/73 ,  A61K6/77 ,  A61K6/65 ,  A61K6/76 ,  A61K6/62 ,  A61K6/17 ,  C08L33/08 ,  C08L33/10 ,  C08L75/06

CPC classification number: A61K6/887 ,  A61C5/73 ,  A61K6/17 ,  A61K6/62 ,  A61K6/65 ,  A61K6/76 ,  A61K6/77 ,  C08L33/08 ,  C08L33/10 ,  C08L75/06

Abstract: The invention relates to A curable composition for producing dental composite crowns, the composition comprising a resin matrix comprising polymerizable (meth)acrylate(s) not comprising a urethane moiety, polymerizable urethane(meth)acrylate(s), wherein the polymerizable (meth)acrylate(s) not comprising an urethane moiety are used in excess over the polymerizable urethane(meth)acrylate(s), a filler matrix comprising nanocluster(s), fumed silica in an amount below 8 wt. % with respect to the weight of the whole composition, an initiator system comprising photoinitiator(s), organic dye(s), the curable composition not comprising softener in an amount of more than 5 wt. % with respect to the weight of the whole composition, the curable composition having a viscosity below 150 Pa*s at 23° C. and a shear rate of 1 s−1. The invention also relates to a cured article obtained by radiation curing this curable composition by use of an additive-manufacturing method.