公开(公告)号：JPH03120469A

公开(公告)日：1991-05-22

申请号：JP26029190

申请日：1990-09-26

Applicant: ABBOTT LAB

Inventor： DONARUDO AABIN SUTEINPUSON ,  DOROSHII ZAKURA

IPC: G01N33/543 ,  G01N30/92 ,  G01N33/545 ,  G01N33/548

Abstract: PURPOSE: To give a mechanical strength to nitrocellulose film while maintaining hydrophilic property by laminating a wet porous film including anion surface-active agent at the final concentration of a specific ratio with its side surface. CONSTITUTION: A wet porous film 10 including anion surface-active agent at a final concentration of approximately 0.05%-8% (w/w) is laminated on a support 14 with at least its one side surface using an adhesive 12 with an organic solvent base, protein is applied to a specific part 15 on the surface on the opposite side, thus bringing a fluid into contact with this opposite side. Then, by bringing it into contact with a biologically active reagent, the activity of the reagent is retained. Preferably, the porous film 10 consists of nitrocellulose and the final concentration of the surface-active agent is approximately 0.1-3.5% (w/w), thus giving mechanical strength to the nitrocellulose while retaining hydrophilic property.

公开(公告)号：JPH03120470A

公开(公告)日：1991-05-22

申请号：JP26029290

申请日：1990-09-26

Applicant: ABBOTT LAB

Inventor： DONARUDO AABIN SUTEINPUSON ,  DOROSHII ZAKURA

IPC: G01N33/543 ,  G01N30/92 ,  G01N33/545 ,  G01N33/548

Abstract: PURPOSE: To give a mechanical strength to nitrocellulose film while retaining hydrophilic property by laminating a porous film that comes into contact with a biologically active reagent and contains an agent of a specific equation at a concentration of a specific ratio. CONSTITUTION: A porous film 10 that comes into contact with a biologically active reagent and contains an agent expressed by R1 N(CH3 )3 SO4 R2 (R1 is a straight chain or a branch chain with 8-18 carbons, R2 is a straight chain or alkyl group with 1-5 carbons) at a concentration of approximately 0.1%-10% (w/w) is laminated on a support 14 with at least its one side surface. The porous film 10 should consist of nitrocellulose and the final concentration of a surface- active agnet is approximately 0.1-0.2% (w/w). Also, the porous film 10 is laminated only at its one side, protein is applied to a specific part 15 on a surface at the opposite side, and a fluid is brought into contact from the opposite side, thus giving mechanical strength to nitrocellulose film while maintaining hydrophilic property.

公开(公告)号：JPH03120468A

公开(公告)日：1991-05-22

申请号：JP26029090

申请日：1990-09-26

Applicant: ABBOTT LAB

Inventor： SHIYAN FUAN CHIN ,  JIYURIAN GOODON ,  TSUNNFUI KEI YOU ,  DONARUDO AABIN SUTEINPUSON ,  DOROSHII ZAKURA ,  PIITAA ZAUN

IPC: G01N30/92 ,  G01N33/543 ,  G01N33/545 ,  G01N33/548 ,  G01N33/558

Abstract: PURPOSE: To give a mechanical strength to a nitrocellulose film while retaining hydrophilic property by laminating a wet porous film on a support with its side surface using a water-soluble solvent base adhesive. CONSTITUTION: A wet porous film 10 is laminated on a support 14 with at least one its side surface using a water-soluble solvent base adhesive 12 and is brought into contact with a biologically active reagent, thus retaining the activity of the reagent. The porous film 10 preferably consists of nitrocellulose and the adhesive 12 consists of adhesive research AS 73. Also, a surface-active agent, preferably alkyl sulfate or sulfone acid alkyl may be included. Then, the water-based solvent base adhesive 12 is used for laminating one surface or both sides of the film 10. When performing lamination only at one side of the film 10, protein is applied to a specific part 15 on the surface at the opposite side and a fluid is brought into contact from the opposite side, thus giving mechanical strength to the nitrocellulose film while retaining hydrophilic property.