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1.PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS 审中-公开
Title translation: 用于合成LHRH拮抗剂的方法和中间体公开(公告)号:WO1997034923A1
公开(公告)日:1997-09-25
申请号:PCT/US1997001912
申请日:1997-02-06
Applicant: ABBOTT LABORATORIES
Inventor: ABBOTT LABORATORIES , FUNK, Kenneth, W. , LUNDELL, Edwin, O. , MILLER, Robert, B. , CHANG, Jane, L. , KISHORE, Vimal , NAPIER, James, J. , STAEGER, Michael, A.
IPC: C07K07/23
CPC classification number: C07K5/06165 , A61K38/00 , C07D307/14 , C07K5/06086 , C07K5/081 , C07K5/0812 , C07K5/0815 , C07K5/1008 , C07K5/1013 , C07K5/1019 , C07K7/23
Abstract: A method is provided for preparing decapeptide and undecapeptide derivatives of LHRH by solution phase peptide chemistry as well as intermediate peptides useful in the same method.
Abstract translation: 提供了通过溶液相肽化学制备LHRH的十肽和十一肽衍生物以及用于相同方法的中间肽的方法。
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2.PROCESS FOR THE PREPARATION OF 1,2,4-OXADIAZOL-3-YL DERIVATIVES OF CARBOXYLIC ACID 审中-公开
Title translation: 制备羧酸的1,2,4-氧杂环丙烷-3-基衍生物的方法公开(公告)号:WO2012122338A1
公开(公告)日:2012-09-13
申请号:PCT/US2012/028203
申请日:2012-03-08
Applicant: ABBOTT LABORATORIES , LUKIN, Kirill A. , KISHORE, Vimal , GORDON, Thomas D.
Inventor: LUKIN, Kirill A. , KISHORE, Vimal , GORDON, Thomas D.
IPC: A61K31/4965
CPC classification number: C07C253/30 , C07C255/54 , C07C255/58 , C07C259/18 , C07C2601/04
Abstract: The present invention discloses processes for the preparation and isolation of [l,2,4]oxadiazo-3-yl derivatives of carboxylic acids. The derivativehe present invention discloses are useful in the treatment of inflammatory diseases and conditions.
Abstract translation: 本发明公开了制备和分离羧酸[1,2,4]恶二唑-3-基衍生物的方法。 本发明的衍生物公开可用于治疗炎性疾病和病症。
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3.PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS 审中-公开
Title translation: 合成LHRH拮抗剂的方法和中间体公开(公告)号:WO1997034924A1
公开(公告)日:1997-09-25
申请号:PCT/US1997001954
申请日:1997-02-06
Applicant: ABBOTT LABORATORIES
Inventor: ABBOTT LABORATORIES , FUNK, Kenneth, W. , LUNDELL, Edwin, O. , MILLER, Robert, B. , CHANG, Jane, L. , KISHORE, Vimal , NAPIER, James, J. , STAEGER, Michael, A.
IPC: C07K07/23
CPC classification number: C07K7/23 , A61K38/00 , C07D307/14
Abstract: A method is provided for preparing decapeptide and undecapeptide derivatives of LHRH by solution phase peptide chemistry as well as intermediate peptides useful in the same method.
Abstract translation: 提供了通过溶液相肽化学制备LHRH的十肽和十一肽衍生物以及以相同方法有用的中间体肽的方法。
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4.METHODS FOR PREPARING S1P RECEPTOR AGONISTS AND ANTAGONISTS 审中-公开
Title translation: 用于制备S1P受体激动剂和拮抗剂的方法公开(公告)号:WO2010093616A1
公开(公告)日:2010-08-19
申请号:PCT/US2010/023607
申请日:2010-02-09
Applicant: ABBOTT LABORATORIES , SHEKHAR, Shashank , YU, Su , HAIGHT, Anthony R. , CHMURA, Preston E. , KISHORE, Vimal
Inventor: SHEKHAR, Shashank , YU, Su , HAIGHT, Anthony R. , CHMURA, Preston E. , KISHORE, Vimal
IPC: A61K31/135
CPC classification number: C07C221/00 , C07B2200/07 , C07C213/02 , C07C213/08 , C07C213/10 , C07C2601/08 , C07C215/42 , C07C217/52 , C07C225/20
Abstract: Disclosed herein are methods of making compounds which are agonists or antagonists of one or more of the individual receptors of the S1P receptor family.
Abstract translation: 本文公开了制备作为S1P受体家族的一种或多种单独受体的激动剂或拮抗剂的化合物的方法。
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公开(公告)号:EP1218338A1
公开(公告)日:2002-07-03
申请号:EP00968815.1
申请日:2000-10-06
Applicant: ABBOTT LABORATORIES
Inventor: RAJE, Prasad, S. , KISHORE, Vimal
IPC: C07C251/24 , C07C269/04 , C07C227/20 , C07D207/46
CPC classification number: C07C251/24 , C07C227/20 , C07C269/04 , C07D207/46 , C07C229/26 , C07C271/22
Abstract: The invention relates to novel processes for preparing differentially protected lysine derivatives via a novel p-anisaldehyde Schiff base intermediate and the intermediate prepared therein.
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6.PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS 失效
Title translation: 过程和中间产品用于LHRH拮抗剂合成公开(公告)号:EP0889901A1
公开(公告)日:1999-01-13
申请号:EP97904253.0
申请日:1997-02-06
Applicant: Abbott Laboratories
Inventor: FUNK, Kenneth, W. , LUNDELL, Edwin, O. , MILLER, Robert, B. , CHANG, Jane, L. , KISHORE, Vimal , NAPIER, James, J. , STAEGER, Michael, A.
CPC classification number: C07K5/06165 , A61K38/00 , C07D307/14 , C07K5/06086 , C07K5/081 , C07K5/0812 , C07K5/0815 , C07K5/1008 , C07K5/1013 , C07K5/1019 , C07K7/23
Abstract: A method is provided for preparing decapeptide and undecapeptide derivatives of LHRH by solution phase peptide chemistry as well as intermediate peptides useful in the same method.
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7.METHODS FOR PREPARING S1P RECEPTOR AGONISTS AND ANTAGONISTS 审中-公开
Title translation: VERFAHRENFÜRDIE HERSTELLUNG VON S1P-REZEPTORAGONISTEN UNDONANTONON公开(公告)号:EP2395986A1
公开(公告)日:2011-12-21
申请号:EP10741615.8
申请日:2010-02-09
Applicant: Abbott Laboratories
Inventor: SHEKHAR, Shashank , YU, Su , HAIGHT, Anthony R. , CHMURA, Preston E. , KISHORE, Vimal
IPC: A61K31/135
CPC classification number: C07C221/00 , C07B2200/07 , C07C213/02 , C07C213/08 , C07C213/10 , C07C2601/08 , C07C215/42 , C07C217/52 , C07C225/20
Abstract: Disclosed herein are methods of making compounds which are agonists or antagonists of one or more of the individual receptors of the S1P receptor family.
Abstract translation: 本文公开了制备作为S1P受体家族的一种或多种单独受体的激动剂或拮抗剂的化合物的方法。
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8.PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS 失效
Title translation: 过程和中间产品用于LHRH拮抗剂合成公开(公告)号:EP0889901B1
公开(公告)日:2001-09-19
申请号:EP97904253.8
申请日:1997-02-06
Applicant: Abbott Laboratories
Inventor: FUNK, Kenneth, W. , LUNDELL, Edwin, O. , MILLER, Robert, B. , CHANG, Jane, L. , KISHORE, Vimal , NAPIER, James, J. , STAEGER, Michael, A.
CPC classification number: C07K5/06165 , A61K38/00 , C07D307/14 , C07K5/06086 , C07K5/081 , C07K5/0812 , C07K5/0815 , C07K5/1008 , C07K5/1013 , C07K5/1019 , C07K7/23
Abstract: A method is provided for preparing decapeptide and undecapeptide derivatives of LHRH by solution phase peptide chemistry as well as intermediate peptides useful in the same method.
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9.PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS 失效
Title translation: 过程和合成的LHRH拮抗剂中间体公开(公告)号:EP0914334B1
公开(公告)日:2001-05-30
申请号:EP97905825.2
申请日:1997-02-06
Applicant: Abbott Laboratories
Inventor: FUNK, Kenneth, W. , LUNDELL, Edwin, O. , MILLER, Robert, B. , CHANG, Jane, L. , KISHORE, Vimal , NAPIER, James, J. , STAEGER, Michael, A.
CPC classification number: C07K7/23 , A61K38/00 , C07D307/14
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10.PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF LHRH ANTAGONISTS 失效
Title translation: 过程和合成的LHRH拮抗剂中间体公开(公告)号:EP0914334A1
公开(公告)日:1999-05-12
申请号:EP97905825.0
申请日:1997-02-06
Applicant: Abbott Laboratories
Inventor: FUNK, Kenneth, W. , LUNDELL, Edwin, O. , MILLER, Robert, B. , CHANG, Jane, L. , KISHORE, Vimal , NAPIER, James, J. , STAEGER, Michael, A.
CPC classification number: C07K7/23 , A61K38/00 , C07D307/14
Abstract: A method is provided for preparing decapeptide and undecapeptide derivatives of LHRH by solution phase peptide chemistry as well as intermediate peptides useful in the same method.
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