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公开(公告)号：AU2005309586A1
公开(公告)日：2006-06-01
申请号：AU2005309586
申请日：2005-11-23
Applicant: ALGORX PHARMACEUTICALS INC
Inventor： ANDERSON TIMOTHY A , BURCH RONALD , LAZAR JEFF
IPC: A61K31/04
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公开(公告)号：WO2006058140A3
公开(公告)日：2007-01-04
申请号：PCT/US2005042578
申请日：2005-11-23
Applicant: ALGORX PHARMACEUTICALS INC , BURCH RONALD , ANDERSON TIMOTHY A , LAZAR JEFF
Inventor： BURCH RONALD , ANDERSON TIMOTHY A , LAZAR JEFF
IPC: A61K31/04
CPC classification number: A61K47/26 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/06 , A61K31/16 , A61K36/81 , A61K47/36 , A61K47/38
Abstract: The present invention provides capsaicinoid gel formulations and methods for relieving pre- and post-surgical pain at a site in a human or animal by administering at a surgical site in a human or animal in need thereof a dose of capsaicinoid gel in an amount effective to attenuate post-surgical pain at the surgical site, the dose of capsaicin ranging from 100 µg to 10,000µg.
Abstract translation: 本发明提供辣椒素类凝胶制剂和方法，其通过在有需要的人或动物的手术部位施用一定剂量的辣椒素凝胶来减轻人或动物的部位的手术前和手术后疼痛， 减轻手术部位的手术后疼痛，辣椒素的剂量范围为100μg〜10,000μg。
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公开(公告)号：CA2596194A1
公开(公告)日：2006-06-01
申请号：CA2596194
申请日：2005-11-23
Applicant: ALGORX PHARMACEUTICALS INC
Inventor： LAZAR JEFF , ANDERSON TIMOTHY A , BURCH RONALD
IPC: A61K31/04
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公开(公告)号：CA2521925A1
公开(公告)日：2004-10-28
申请号：CA2521925
申请日：2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC
Inventor： CARTER RICHARD B , ANDERSON TIMOTHY A , BURCH RONALD , RAMIYA PREMCHANDRAN H , CHEN WEI , MCILVAIN SHARON
IPC: C07C233/22 , A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
Abstract: The present invention provides methods for synthesizing the trans isomer of capsaicin and/or capsaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carri ed through the entire synthesis process.
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公开(公告)号：WO2004092122A3
公开(公告)日：2005-12-29
申请号：PCT/US2004010745
申请日：2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC , MCILVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRAN H , BURCH RONALD , CARTER RICHARD B , ANDERSON TIMOTHY A , ZHANG HEPING
Inventor： MCILVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRAN H , BURCH RONALD , CARTER RICHARD B , ANDERSON TIMOTHY A , ZHANG HEPING
IPC: A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
CPC classification number: C07C231/02 , A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , A61K2300/00 , C07C57/03 , C07C233/20
Abstract: The present invention provides methods for synthesizing the trans isomer of capsaicin and/or capsaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carried through the entire synthesis process.
Abstract translation: 本发明提供了通过利用反应几何形式从合成反应开始设定并通过整个合成过程进行的方法来合成辣椒素和/或辣椒素样化合物的反式异构体的方法。
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Patent Agency Ranking
公开(公告)号：BRPI0516912A2
公开(公告)日：2009-06-23
申请号：BRPI0516912
申请日：2005-11-23
Applicant: ALGORX PHARMACEUTICALS INC
Inventor： BURCH RONALD , ANDERSON TIMOTHY A , LAZAR JEFF
IPC: A61K31/04
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公开(公告)号：NZ542887A
公开(公告)日：2008-05-30
申请号：NZ54288704
申请日：2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC
Inventor： MCILVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRAN H , BURCH RONALD , CARTER RICHARD B , ANDERSON TIMOTHY A , ZHANG HEPING
IPC: A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
Abstract: Disclosed are methods for synthesizing the trans isomer of capasaicin and/or capasaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carried through the entire synthesis process.
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公开(公告)号：EA008705B1
公开(公告)日：2007-06-29
申请号：EA200501582
申请日：2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC
Inventor： MCINVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRAN H , BIRCH RONALD , CARTER RICHARD B , ANDERSON TIMOTHY A , ZHANG HEPING
IPC: A61K31/165 , A61K31/05 , A61K31/16 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
Abstract: Внастоящемизобретениипредложенспособсинтезатранс-изомеракапсаицинаи/иликапсаициноподобныхсоединений, путемиспользованияпроцесса, вкоторомтранс-конфигурациюзадаютс самогоначалареакциисинтезаи сохраняютеенапротяжениивсегопроцессасинтеза.
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公开(公告)号：BRPI0409748A
公开(公告)日：2006-10-24
申请号：BRPI0409748
申请日：2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC
Inventor： MCIIVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRAN H , BURCH RONALD , CARTER RICHARD , ANDERSON TIMOTHY A
IPC: A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
Abstract: The present invention provides methods for synthesizing the trans isomer of capsaicin and/or capsaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carried through the entire synthesis process.
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公开(公告)号：EP1615880A4
公开(公告)日：2007-03-07
申请号：EP04749854
申请日：2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC
Inventor： MCILVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRAN H , BURCH RONALD , CARTER RICHARD B , ANDERSON TIMOTHY A , ZHANG HEPING
IPC: A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
CPC classification number: C07C231/02 , A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , A61K2300/00 , C07C57/03 , C07C233/20
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