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1.
公开(公告)号:WO2004092122A3
公开(公告)日:2005-12-29
申请号:PCT/US2004010745
申请日:2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC , MCILVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRAN H , BURCH RONALD , CARTER RICHARD B , ANDERSON TIMOTHY A , ZHANG HEPING
Inventor: MCILVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRAN H , BURCH RONALD , CARTER RICHARD B , ANDERSON TIMOTHY A , ZHANG HEPING
IPC: A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
CPC classification number: C07C231/02 , A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , A61K2300/00 , C07C57/03 , C07C233/20
Abstract: The present invention provides methods for synthesizing the trans isomer of capsaicin and/or capsaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carried through the entire synthesis process.
Abstract translation: 本发明提供了通过利用反应几何形式从合成反应开始设定并通过整个合成过程进行的方法来合成辣椒素和/或辣椒素样化合物的反式异构体的方法。
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公开(公告)号:AR055274A1
公开(公告)日:2007-08-15
申请号:ARP050104230
申请日:2005-10-07
Applicant: ALGORX PHARMACEUTICALS INC
Inventor: MC ILVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRA , BURCH RONALD B , CARTER RICHARD B , ANDERSON THIMOTHY
IPC: C07C233/02
Abstract: La presente provee métodos para sintetizar el trans isomero de la capsaicina y/o compuestos similares a la capsaicina utilizando un proceso en donde la trans geometría se encuentra configurada desde el principio de la reaccion de síntesis y llevada a lo largo de todo el proceso de síntesis.
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公开(公告)号:CA2521925A1
公开(公告)日:2004-10-28
申请号:CA2521925
申请日:2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC
Inventor: CARTER RICHARD B , ANDERSON TIMOTHY A , BURCH RONALD , RAMIYA PREMCHANDRAN H , CHEN WEI , MCILVAIN SHARON
IPC: C07C233/22 , A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
Abstract: The present invention provides methods for synthesizing the trans isomer of capsaicin and/or capsaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carri ed through the entire synthesis process.
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公开(公告)号:AU2004230915A1
公开(公告)日:2004-10-28
申请号:AU2004230915
申请日:2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC
Inventor: MCILVAIN SHARON , RAMIYA PREMCHANDRAN H , CARTER RICHARD B , ANDERSON THIMOTHY A , BURCH RONALD , CHEN WEI
IPC: A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
Abstract: The present invention provides methods for synthesizing the trans isomer of capsaicin and/or capsaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carried through the entire synthesis process.
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公开(公告)号:AU2004230915B2
公开(公告)日:2008-08-07
申请号:AU2004230915
申请日:2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC
Inventor: MCILVAIN SHARON , RAMIYA PREMCHANDRAN H , CARTER RICHARD B , ANDERSON THIMOTHY A , BURCH RONALD , CHEN WEI
IPC: A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
Abstract: The present invention provides methods for synthesizing the trans isomer of capsaicin and/or capsaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carried through the entire synthesis process.
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公开(公告)号:NZ542887A
公开(公告)日:2008-05-30
申请号:NZ54288704
申请日:2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC
Inventor: MCILVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRAN H , BURCH RONALD , CARTER RICHARD B , ANDERSON TIMOTHY A , ZHANG HEPING
IPC: A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
Abstract: Disclosed are methods for synthesizing the trans isomer of capasaicin and/or capasaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carried through the entire synthesis process.
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公开(公告)号:EA008705B1
公开(公告)日:2007-06-29
申请号:EA200501582
申请日:2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC
Inventor: MCINVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRAN H , BIRCH RONALD , CARTER RICHARD B , ANDERSON TIMOTHY A , ZHANG HEPING
IPC: A61K31/165 , A61K31/05 , A61K31/16 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
Abstract: Внастоящемизобретениипредложенспособсинтезатранс-изомеракапсаицинаи/иликапсаициноподобныхсоединений, путемиспользованияпроцесса, вкоторомтранс-конфигурациюзадаютс самогоначалареакциисинтезаи сохраняютеенапротяжениивсегопроцессасинтеза.
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公开(公告)号:BRPI0409748A
公开(公告)日:2006-10-24
申请号:BRPI0409748
申请日:2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC
Inventor: MCIIVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRAN H , BURCH RONALD , CARTER RICHARD , ANDERSON TIMOTHY A
IPC: A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
Abstract: The present invention provides methods for synthesizing the trans isomer of capsaicin and/or capsaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carried through the entire synthesis process.
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9.
公开(公告)号:EP1615880A4
公开(公告)日:2007-03-07
申请号:EP04749854
申请日:2004-04-08
Applicant: ALGORX PHARMACEUTICALS INC
Inventor: MCILVAIN SHARON , CHEN WEI , RAMIYA PREMCHANDRAN H , BURCH RONALD , CARTER RICHARD B , ANDERSON TIMOTHY A , ZHANG HEPING
IPC: A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , C07C231/02 , C07C233/20 , C07D201/00
CPC classification number: C07C231/02 , A61K31/05 , A61K31/16 , A61K31/165 , A61K31/5415 , A61K31/551 , A61K45/06 , C07C51/36 , A61K2300/00 , C07C57/03 , C07C233/20
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