中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

46 records (took 0.022 seconds)

    METHOD OF PRODUCING 3,4-DEHYDROPROLINES AND 3,4-DEHYDROPIPERIDINES
    5.
    发明专利
    METHOD OF PRODUCING 3,4-DEHYDROPROLINES AND 3,4-DEHYDROPIPERIDINES 未知

    公开(公告)号：CA2368479A1

    公开(公告)日：2000-10-05

    申请号：CA2368479

    申请日：2000-03-17

    Applicant: BASF AG

    Inventor： KAZMAIER ULI ,  STAHR HELMUT ,  WOLFART VOLKER ,  SCHLEICH SIMONE ,  SCHAFER BERND ,  HELMCHEN GUNTER

    IPC: C07D211/78 ,  C07D207/16 ,  C07D207/20 ,  C07D211/70 ,  C07D207/22

    Abstract: The invention relates to a method for producing compounds of the general formula (I) in which R is hydrogen, C1-C6-alkoxy, -NHC1-C6-alkyl, -N(C1-C6- alkyl)2, OH, NH2; R1 is hydrogen, C1-C6-alkyl, Me3Si, C1-C6-alkyl-S; R2 is Boc, C1-C6-acyl, mesyl, benzolsulfonyl, tosyl, trifluoroacetyl, A1-A3-peptid e; n is 1, 2; and R4 is H, C1-C6-alkyl rest. According to said method a pyrroli ne or dehydropiperidine derivative of the general formula (II) is reacted with a strong base and a compound of the general formula (III), in which Y is Cl, C 1- C6-alkoxy, -NHC1-C6-alkyl, -N(C1-C6-alkyl)2, N(C1-C6-alkyl) OC1-C6, where R is not equal OH, or with carbon dioxide when R = OH. The reaction product of (I I) and (III) is possibly hydrolyzed or reacted with a compound of the general formula (IV) R1~X, in which X is Cl, Br, I, MesO, TosO, triflate, R1 is hydrogen, C1-C6-alkyl, Me3Si, C1-C6-alkyl-S or NH4, or R1~X is (C1-C6-alkyl- 'S)2.

    7.
    发明专利
    未知

    公开(公告)号：TR200200181T2

    公开(公告)日：2002-08-21

    申请号：TR200200181

    申请日：2000-07-11

    Applicant: BASF AG

    Inventor： KNOPP MONIKA ,  KOSER STEFAN ,  SCHAFER BERND

    IPC: C07D277/20 ,  C07D277/56

    Abstract: The invention relates to processes for preparing 2-aminomethyl-4-cyanothiazole and its salts of the formulae Ia and Ibin whichn=1 or 2 andfor n=1, X is chloride, bromide, triflate and hydrogen sulfate andfor n=2, X is sulfate, which comprises the process step where the aminonitrile of the formula IIis stirred with a cysteine ester of the formula III,in which R is branched or linear C1-10-alkyl orwhere n=0, 1 or 2 and R is branched or linear C1-C10C10-alkyl or C1-C4-alkoxy or C1-C4-dialkylamino in an inert solvent in the presence of a base at from 0° C. to 80° C. until the reaction has essentially proceeded to completion, and to the compounds of the formulae Ia and Ib.

    METHOD FOR PRODUCING 4-CYANO-2-AMINOMETHYLTHIAZOL
    8.
    发明专利
    METHOD FOR PRODUCING 4-CYANO-2-AMINOMETHYLTHIAZOL 未知

    公开(公告)号：SK1062002A3

    公开(公告)日：2002-07-02

    申请号：SK1062002

    申请日：2000-07-11

    Applicant: BASF AG

    Inventor： KNOPP MONIKA ,  KOSER STEFAN ,  SCHAFER BERND

    IPC: C07D277/20 ,  C07D277/56

    Abstract: The invention relates to processes for preparing 2-aminomethyl-4-cyanothiazole and its salts of the formulae Ia and Ibin whichn=1 or 2 andfor n=1, X is chloride, bromide, triflate and hydrogen sulfate andfor n=2, X is sulfate, which comprises the process step where the aminonitrile of the formula IIis stirred with a cysteine ester of the formula III,in which R is branched or linear C1-10-alkyl orwhere n=0, 1 or 2 and R is branched or linear C1-C10C10-alkyl or C1-C4-alkoxy or C1-C4-dialkylamino in an inert solvent in the presence of a base at from 0° C. to 80° C. until the reaction has essentially proceeded to completion, and to the compounds of the formulae Ia and Ib.

Patent Agency Ranking