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    MULTI-FUNCTION ELECTRODE STRUCTURES FOR ELECTRICALLY ANALYZING AND HEATING BODY TISSUE
    1.
    发明申请
    MULTI-FUNCTION ELECTRODE STRUCTURES FOR ELECTRICALLY ANALYZING AND HEATING BODY TISSUE 审中-公开
    用于电动分析和加热身体组织的多功能电极结构

    公开(公告)号：WO1997025917A1

    公开(公告)日：1997-07-24

    申请号：PCT/US1997000896

    申请日：1997-01-17

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  PANESCU, Dorin ,  SWANSON, David, K. ,  WHAYNE, James, G. ,  JACKSON, Jerome

    IPC: A61B05/04

    CPC classification number: A61N1/06 ,  A61B18/1492 ,  A61B2018/00065 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/00113 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00839 ,  A61B2018/1253 ,  A61B2018/1472 ,  A61B2218/002 ,  A61L29/085 ,  A61L29/145 ,  A61L31/10 ,  A61L31/145 ,  C08L1/02

    Abstract: Systems and methods for heating body tissue places a multi-function structure (22) having an exterior wall in contact with body tissue. The structure includes an array of electrically conducting electrode segments (44) carried by the exterior wall. An electrically conductive network is coupled to the electrode segments, including at least one electrically conductive path (32) individually coupled to each electrode segment. The systems and methods operate in a first mode during which the network is electrically conditioned to individually sense at each electrode segment local electrical events in tissue, such as electrical potentials, resistivity, or impedance. The systems and methods operate in a second mode during which the network is electrically conditioned, based at least in part upon local electrical events sensed by the electrode segments, to couple at least two electrode segments together to simultaneously trasmit electrical energy to heat or ablate a region of body tissue.

    Abstract translation: 用于加热身体组织的系统和方法将具有外壁的多功能结构（22）与身体组织接触。 该结构包括由外壁承载的导电电极段（44）阵列。 导电网络耦合到电极段，包括分别耦合到每个电极段的至少一个导电路径（32）。 系统和方法以第一模式操作，在该模式期间，网络经电气调节以在每个电极段处单独感测组织中的局部电气事件，例如电势，电阻率或阻抗。 系统和方法在第二模式下操作，其中网络被电调节，至少部分地基于由电极段感测的局部电气事件，以将至少两个电极段耦合在一起，以同时对电能进行加热或消融 身体组织区域。

    MINIMIZING BLOOD CONTACT IN CARDIAC TISSUE MEASUREMENTS
    3.
    发明申请
    MINIMIZING BLOOD CONTACT IN CARDIAC TISSUE MEASUREMENTS 审中-公开
    在心脏组织测量中最小化血液联系

    公开(公告)号：WO1995020345A1

    公开(公告)日：1995-08-03

    申请号：PCT/US1995001112

    申请日：1995-01-27

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  SWANSON, David, K. ,  PANESCU, Dorin

    IPC: A61B05/04

    CPC classification number: A61B5/6855 ,  A61B5/0422 ,  A61B5/0536 ,  A61B5/6858 ,  A61B18/00 ,  A61B18/1492 ,  A61B2562/0209 ,  A61B2562/043

    Abstract: Systems (10) for examining heart tissue morphology deploy one or more electrodes (38) into the heart in contact with endocardial tissue. The systems transmit electrical current from the electrodes (38) in paths through the contacted endocardial tissue. Based upon these current transmissions, the systems derive the electrical characteristics of tissue lying in the path. This electrical characteristc can be directly correlated to tissue morphology. The systems maximize surface contact with endocardial tissue, while minimizing contact with the surrounding blood pool, to obtain accurate tissue electrical characteristic measurements.

    Abstract translation: 用于检查心脏组织形态的系统（10）将一个或多个电极（38）部署到与心内膜组织接触的心脏中。 该系统在通过所接触的心内膜组织的路径中从电极（38）传输电流。 基于这些当前传输，系统导出位于路径中的组织的电特性。 这种电学特征可以直接与组织形态相关。 系统最大限度地与心内膜组织的表面接触，同时最小化与周围血液池的接触，以获得精确的组织电特征测量。

    FLEXIBLE CIRCUIT ASSEMBLIES EMPLOYING RIBBON CABLE
    4.
    发明申请
    FLEXIBLE CIRCUIT ASSEMBLIES EMPLOYING RIBBON CABLE 审中-公开
    使用RIBBON电缆的柔性电路组件

    公开(公告)号：WO1994021170A1

    公开(公告)日：1994-09-29

    申请号：PCT/US1994002811

    申请日：1994-03-15

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  KORDIS, Thomas, F. ,  SWANSON, David, K. ,  PANESCU, Dorin

    IPC: A61B05/04

    CPC classification number: A61B5/6858 ,  A61B5/0422 ,  A61B18/1492 ,  A61B2018/00267 ,  A61B2018/1407 ,  A61B2018/1435 ,  A61B2562/0209 ,  A61B2562/043

    Abstract: An electrode circuit (34) has a distal region (32) for carrying at least one electrode, a proximal region (30) for connection to an external apparatus, and an intermediate region electrically coupling the distal region with the proximal region. At least one, and preferably all, of the regions comprises a flexible ribbon cable having two or more adjacent tracks (T1-T6) of electrical conduction material and adjoining electrical insulating material. Use of ribbon cable makes possible reliable connections without the need for complicated multiplexing schemes at the distal region.

    Abstract translation: 电极电路（34）具有用于承载至少一个电极的远端区域（32），用于连接到外部设备的近端区域（30）以及将远侧区域与近端区域电耦合的中间区域。 至少一个，优选地，所有这些区域包括具有导电材料和邻接电绝缘材料的两个或多个相邻轨道（T1-T6）的柔性带状电缆。 使用带状电缆使得可靠的连接成为可能，而不需要在远端区域进行复杂的复杂方案。

    SYSTEMS AND METHODS FOR EXAMINING HEART TISSUE
    7.
    发明申请
    SYSTEMS AND METHODS FOR EXAMINING HEART TISSUE 审中-公开
    用于检查心脏组织的系统和方法

    公开(公告)号：WO1996025097A1

    公开(公告)日：1996-08-22

    申请号：PCT/US1996002190

    申请日：1996-02-16

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  SWANSON, David, K. ,  PANESCU, Dorin ,  WHAYNE, James, G.

    IPC: A61B05/0402

    CPC classification number: A61B5/6855 ,  A61B5/0422 ,  A61B5/6858 ,  A61B18/1492 ,  A61B2090/065 ,  A61B2562/0209 ,  A61B2562/043 ,  A61N1/056

    Abstract: Systems and methods use an array (20) of multiple electrodes (24) supported for operative association with a region of heart tissue, in tandem with a roving second electrode (36) supported for movement relative to the multiple electrodes for operative association with selected different regions of endocardial tissue within the heart. An analog or digital processing element (32) conditions one of the multiple electrodes and the roving electrode to emit a pacing signal while the other one of the multiple electrodes and the roving electrode records paced electro-grams occurring as a result of the pacing signal. A template of cardiac event of known diagnosis sensed using the array of multiple electrodes is input. A sample of a cardiac event acquired by pacing from at least one roving electrode and sensed with the array of multiple electrodes is input. The processing element and method electronically compare the sample to a template and generate an output.

    Abstract translation: 系统和方法使用多个电极（24）的阵列（20），其被支撑用于与心脏组织的区域有效地相关联，与被支撑用于相对于多个电极移动的粗纱第二电极（36）串联，以与所选择的不同的 心脏内心脏组织的区域。 模拟或数字处理元件（32）调节多个电极和粗纱电极之一以发出起搏信号，而多个电极和粗纱电极中的另一个记录起搏电针作为起搏信号的结果。 输入使用多个电极阵列感测的已知诊断的心脏事件的模板。 输入通过起搏从至少一个粗纱电极获取的心脏事件的样本，并用多个电极的阵列感测。 处理元件和方法将样本与模板进行电子比较并生成输出。

    SYSTEMS AND METHODS FOR FILTERING SIGNALS DERIVED FROM BIOLOGICAL EVENTS
    8.
    发明申请
    SYSTEMS AND METHODS FOR FILTERING SIGNALS DERIVED FROM BIOLOGICAL EVENTS 审中-公开
    用于过滤生物活动信号的系统和方法

    公开(公告)号：WO1996025093A1

    公开(公告)日：1996-08-22

    申请号：PCT/US1996001977

    申请日：1996-02-16

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  PANESCU, Dorin ,  WHAYNE, James, G. ,  SWANSON, David, K.

    IPC: A61B05/0402

    CPC classification number: H03H17/0263 ,  A61B5/0422 ,  A61B5/6855 ,  A61B5/6858 ,  A61B2562/0209 ,  A61B2562/043 ,  A61N1/3702

    Abstract: Systems and methods provide nonlinear, non-median filters (56) for signals derived from biological events. The systems and methods select a set of n sample values arranged with respect to time from the derived biological signal input. The systems and methods arrange the n sample values of the set into ordered positions following a predetermined permutation. The systems and methods select one of the ordered positions z within the permutation, where z is an odd positive integer greater or equal to one but less than or equal to n. The systems and methods generate a processed output (54) comprising the sample value occupying the ordered position z in the permutation.

    Abstract translation: 系统和方法为来自生物事件的信号提供非线性非中值滤波器（56）。 系统和方法从衍生的生物信号输入中选择相对于时间排列的一组n个样本值。 系统和方法将集合的n个样本值排列在预定排列之后的有序位置。 系统和方法选择置换中的有序位置z之一，其中z是大于或等于1但小于或等于n的奇正整数。 系统和方法产生包括在排列中占据有序位置z的样本值的经处理的输出（54）。

    SYSTEMS AND METHODS FOR EXAMINING ELECTRICAL EVENTS
    10.
    发明申请
    SYSTEMS AND METHODS FOR EXAMINING ELECTRICAL EVENTS 审中-公开
    用于检查电气事件的系统和方法

    公开(公告)号：WO1995020347A1

    公开(公告)日：1995-08-03

    申请号：PCT/US1995001121

    申请日：1995-01-27

    Applicant: EP TECHNOLOGIES, INC.

    Inventor： EP TECHNOLOGIES, INC. ,  PANESCU, Dorin ,  SWANSON, David, K. ,  MIROTZNIK, Mark, S. ,  SCHWARTZMAN, David, S.

    IPC: A61B05/04

    CPC classification number: A61B5/6855 ,  A61B5/0422 ,  A61B5/0452 ,  A61B5/0535 ,  A61B5/0538 ,  A61B5/6858 ,  A61B18/14 ,  A61B18/1492 ,  A61B2017/003 ,  A61B2018/00214 ,  A61B2018/00755 ,  A61B2018/00761 ,  A61B2018/00875 ,  A61B2018/00886 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1273 ,  A61B2018/128 ,  A61B2562/0209 ,  A61B2562/043

    Abstract: This invention is systems and methods to examine heart tissue morphology using a pair of electrodes (38), at least one of which is located in contact with heart tissue (12). The systems and methods transmit electrical current in a path through the contacted heart tissue (12) between the pair of the electrodes to derive a tissue electrical characteristic based, at least in part, upon sensing the impedance of the tissue lying in the path. The system and methods also sense with at least one of the electrodes the timing of local depolarization events in the contacted heart tissue. The systems and methods make possible the use of multiple endocardial electrodes (30) for taking multiple measurements of the electrical characteristics of heart tissue. Multiplexing can be used to facilitate data processing. The systems and methods also make possible the identification of regions of low relative electrical characteristics, indicative of infarcted tissue, without invasive surgical techniques.

    Abstract translation: 本发明是使用一对电极（38）检查心脏组织形态的系统和方法，其中至少一个位于与心脏组织（12）接触的位置。 所述系统和方法在通过所述一对电极之间的所接触的心脏组织（12）的路径中传输电流，以至少部分地基于感测位于所述路径中的组织的阻抗而导出组织电特征。 该系统和方法还与至少一个电极一起感知接触的心脏组织中局部去极化事件的定时。 系统和方法使得可以使用多个心内膜电极（30）来进行心脏组织的电特性的多次测量。 可以使用多路复用来促进数据处理。 系统和方法还可以鉴定低相对电特征的区域，指示梗死组织，无侵入性手术技术。

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