公开(公告)号：US20190233858A1

公开(公告)日：2019-08-01

申请号：US16264798

申请日：2019-02-01

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Massimiliano ZAMPINI ,  Alexander Brett FOSTER

IPC: C12P13/08 ,  C12N15/74 ,  C12N9/88

CPC classification number: C12P13/08 ,  C12N9/88 ,  C12N15/74 ,  C12Y401/01018

Abstract: Methods and materials for the biosynthesis of compounds involved in lysine metabolism and/or derivatives and/or compounds related thereto are provided. Also provided are products produced in accordance with these methods and materials.

公开(公告)号：US20200157582A1

公开(公告)日：2020-05-21

申请号：US16685290

申请日：2019-11-15

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alexander STEINBÜCHEL ,  Jessica EGGERS ,  Alexander Brett FOSTER ,  Jonathan KENNEDY

IPC: C12P7/16 ,  C12N1/20 ,  C12R1/01

Abstract: Nonnaturally occurring organisms exhibiting improved carbon utilization and methods for production and use of these nonnaturally occurring organisms in chemical production from carbon containing feedstocks are provided.

公开(公告)号：US20190338320A1

公开(公告)日：2019-11-07

申请号：US16399155

申请日：2019-04-30

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alexander Brett FOSTER ,  Cristina Serrano AMATRIAIN ,  Gary J. Smith ,  Paul Sheldon Pearlman ,  Mark Paul Taylor

IPC: C12P7/62

Abstract: Provided herein are methods for generating cellular biomass in continuous aerobic fermentation systems. The biomass yield, and the concentration of polyhydroxyalkanoate within the biomass, are each directed to advantageous levels by operating the continuous fermentation system under particular nutrient limitation conditions. Also provided are biomass produced using the provided methods, and animal feed compositions including the provided biomass.

公开(公告)号：US20190337995A1

公开(公告)日：2019-11-07

申请号：US16398365

申请日：2019-04-30

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alexander Brett FOSTER ,  Ana Teresa dos Santos Brito Mendes ROBERTS ,  Arghya BARMAN ,  Jonathan KENNEDY

IPC: C07K14/195 ,  C12P7/56 ,  C12P7/42 ,  C12P7/54 ,  C12P7/18

Abstract: Methods for increasing carbon-based chemical product yield in an organism by increasing carbon uptake and/or altering a pathway to or from an overflow metabolite in the organism, nonnaturally occurring organisms having increased carbon-based chemical product yield with increased carbon uptake and/or an altered pathway to or from an overflow metabolite, and methods for producing a carbon-based chemical product with these organisms are provided.

公开(公告)号：US20190233850A1

公开(公告)日：2019-08-01

申请号：US16264759

申请日：2019-02-01

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Ana Teresa dos Santos Brito Mendes ROBERTS ,  Alexander Brett FOSTER

IPC: C12P7/42 ,  C12N15/74 ,  C12N9/02

CPC classification number: C12P7/42 ,  C12N9/0008 ,  C12N15/74 ,  C12Y102/01075

Abstract: Methods and materials for the production of beta hydroxy acids, such as 3-hydroxypropanoic acid (3-HP) and derivatives and compounds related thereto are provided. Also provided are products produced in accordance with these methods and materials.

公开(公告)号：US20190233848A1

公开(公告)日：2019-08-01

申请号：US16264768

申请日：2019-02-01

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Nadia Fatma KADI ,  Daniel BAWDON ,  Alexander Brett FOSTER

IPC: C12P7/18 ,  C12N15/74 ,  C12N9/04 ,  C12N9/88 ,  C12N9/12

CPC classification number: C12P7/18 ,  C12N9/0006 ,  C12N9/1205 ,  C12N9/88 ,  C12N15/74 ,  C12Y101/01006 ,  C12Y101/01077 ,  C12Y101/01283 ,  C12Y207/01029 ,  C12Y402/03003

Abstract: Methods and materials for the production of diol alcohols, such as 1,2-propanediol (1,2-PD) and derivatives and compounds related thereto. Also provided are products produced in accordance with these methods and materials.

公开(公告)号：US20180273987A1

公开(公告)日：2018-09-27

申请号：US15903744

申请日：2018-02-23

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Nadia Fatma KADI ,  Mariusz Stanislaw KAMIONKA ,  Alexander Brett FOSTER ,  Alex Van Eck CONRADIE ,  Adriana Leonora BOTES

IPC: C12P7/62 ,  C12N9/02 ,  C07C69/42 ,  C12N9/10 ,  C12N9/16 ,  C12N15/52 ,  C12P13/00 ,  C12P7/42 ,  C12P7/44 ,  C07C229/08 ,  C12N9/18

CPC classification number: C12P7/62 ,  C07C69/42 ,  C07C229/08 ,  C12N9/0008 ,  C12N9/1007 ,  C12N9/1096 ,  C12N9/16 ,  C12N9/18 ,  C12N15/52 ,  C12P7/42 ,  C12P7/44 ,  C12P13/001 ,  C12Y102/99006 ,  C12Y201/01197 ,  C12Y206/01018 ,  C12Y206/01038 ,  C12Y301/01085

Abstract: This document describes biochemical pathways for producing 2,4-pentadienoyl-CoA by forming one or two terminal functional groups, comprised of carboxyl or hydroxyl group, in a C5 backbone substrate such as glutaryl-CoA, glutaryl-[acp] or glutarate methyl ester. 2,4-pentadienoyl-CoA can be enzymatically converted to 1,3-butadiene.

公开(公告)号：US20190352674A1

公开(公告)日：2019-11-21

申请号：US16399145

申请日：2019-04-30

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alexander Brett FOSTER ,  Cristina Serrano AMATRIAIN ,  Gary J. Smith ,  Paul Sheldon Pearlman ,  Mark Paul Taylor ,  Jonathan Combe ,  Daniel Bawdon

IPC: C12P7/04 ,  C12N1/20 ,  C12P7/06 ,  C12P7/42 ,  C12N9/10 ,  C12N9/88 ,  C12N9/04

Abstract: Provided herein are methods for increasing the yield of an extracellular product synthesized by an organism cultured in a continuous aerobic fermentation system. The extracellular product yield is increased through the use of an organism modified to decreased production of polyhydroxyalkanoate, to increase production of the extracellular product, and to include promoters that can be inducible in response to nutrient limitation conditions. The extracellular product yield is also increased by operating the continuous fermentation system under particular nutrient limitation conditions. Also provided are non-naturally occurring organisms that have been modified for use with the provided methods, and extracellular products made using the provided methods.

公开(公告)号：US20190338377A1

公开(公告)日：2019-11-07

申请号：US16398401

申请日：2019-04-30

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alexander Brett FOSTER ,  Emilie Sophie FRITSCH

IPC: C12R1/38 ,  C12N9/02 ,  C12N15/68 ,  C12N15/52 ,  C12N9/14 ,  C12P7/16

Abstract: Methods of redirecting carbon flux and increasing C2/C3 or a C4/5/6 carbon chain length carbon-based chemical product yield in an organism, nonnaturally occurring organisms with redirected carbon flux and increased C2/C3 or C4/5/6 carbon chain length carbon-based chemical product yield and methods for using these organisms in production of C2/C3 or C4/5/6 carbon chain length carbon-based chemical products are provided.

公开(公告)号：US20190233851A1

公开(公告)日：2019-08-01

申请号：US16264782

申请日：2019-02-01

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Jonathan KENNEDY ,  Alexander Brett FOSTER

IPC: C12P7/42 ,  C12N9/16 ,  C12N9/02 ,  C12N9/88 ,  C12N9/00 ,  C12N15/52 ,  C12R1/01

CPC classification number: C12P7/42 ,  C12N9/001 ,  C12N9/16 ,  C12N9/88 ,  C12N9/93 ,  C12N15/52 ,  C12R1/01 ,  C12Y103/01039 ,  C12Y301/02007 ,  C12Y401/99005 ,  C12Y602/01003

Abstract: Methods and materials for the production of compounds involved in fatty acid metabolism, and/or derivatives thereof and/or compounds related thereto are provided. Also provided are products produced in accordance with the methods and materials of the present invention.