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    SEALING CASE FOR FILTER CASSETTE
    92.
    发明申请
    SEALING CASE FOR FILTER CASSETTE 审中-公开
    密封件用于过滤器CASSETTE

    公开(公告)号：WO2017003625A1

    公开(公告)日：2017-01-05

    申请号：PCT/US2016/035133

    申请日：2016-06-01

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： HILLIER, Brian

    IPC: B01D61/08 ,  B01D61/10

    CPC classification number: B01D65/003 ,  B01D63/082 ,  B01D2313/04 ,  B01D2315/10

    Abstract: A sealing case for a filtration cassette that reliably prevents leaks after assembly and installation into a filtration system. The sealing case fits on the filtration cassette and provides a fluid-tight seal between the sealing case and around at least one port in the filtration cassette when installed in a filtration system. The sealing case may comprise two halves that mate together, and each half may be identical. The internal surface of the sealing case is flat or substantially flat.

    Abstract translation: 用于过滤盒的密封箱，其可靠地防止在组装和安装到过滤系统中之后的泄漏。 密封套装在过滤盒上，并且当安装在过滤系统中时，在密封箱和过滤盒中的至少一个端口之间提供流体密封。 密封箱可以包括配合在一起的两半，并且每一半可以是相同的。 密封箱的内表面是平坦的或基本平坦的。

    MODULAR AERATION DEVICE
    96.
    发明申请
    MODULAR AERATION DEVICE 审中-公开
    模块化设备

    公开(公告)号：WO2015065647A1

    公开(公告)日：2015-05-07

    申请号：PCT/US2014/058942

    申请日：2014-10-03

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： WOOD, Amy ,  KRAUS, Dave ,  HANSEN, Anne ,  DER, Kara ,  MCSWEENEY, James

    IPC: B01F3/04

    CPC classification number: C12M27/02 ,  B01F3/04269 ,  B01F3/04531 ,  B01F7/22 ,  B01F13/0863 ,  B01F15/0022 ,  B01F15/00344 ,  B01F15/0085 ,  B01F2003/04297 ,  B01F2003/04631 ,  B01F2003/04673 ,  B01F2215/0073 ,  C12M29/06 ,  C12Q3/00

    Abstract: An aeration device, and containers or vessels incorporating the same. The aeration device can comprise a plurality of interchangeable aeration elements that can produce gas bubble of different sizes and deliver them to the contents of the container. Also disclosed are containers, such as a disposable or single-use container, optionally having one or more inlets and one or more outlets, an aeration device including a plurality of aeration elements, and a mixer to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The container can be a bioreactors and the aeration device controls the dissolved gas concentration content of the bioreactor contents, thereby facilitating proper growth of cell cultures in the bioreactor.

    Abstract translation: 曝气装置，以及装有该装置的容器或容器。 曝气装置可以包括多个可互换曝气元件，其可以产生不同尺寸的气泡并将其输送到容器的内容物。 还公开了容器，例如一次性或一次性容器，任选地具有一个或多个入口和一个或多个出口，包括多个通气元件的曝气装置和用于引起混合，分散，均质和/或 包含或添加到容器中的一种或多种成分的循环。 容器可以是生物反应器，曝气装置控制生物反应器内容物的溶解气体浓度含量，从而促进生物反应器中细胞培养物的适当生长。

    FLEXIBLE FILM BAFFLE IN SINGLE USE BIOREACTOR
    97.
    发明申请
    FLEXIBLE FILM BAFFLE IN SINGLE USE BIOREACTOR 审中-公开
    柔性膜在单一使用生物反应器

    公开(公告)号：WO2014172047A1

    公开(公告)日：2014-10-23

    申请号：PCT/US2014/030140

    申请日：2014-03-17

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： DER, Kara ,  HANSEN, Anne ,  MCSWEENEY, James ,  KRAUS, David ,  PEARSONS, Jeffrey ,  WOOD, Amy

    IPC: B01F7/16

    CPC classification number: C12M27/20 ,  B01F7/021 ,  B01F13/0872 ,  B01F15/0085 ,  B01F15/00915 ,  C12M23/22 ,  C12M23/26 ,  C12M23/28 ,  C12M25/16 ,  C12M27/02

    Abstract: A container, such as a disposable or single use bioreactor, optionally having one or more inlets and one or more outlets and a mixer associated with the container to cause mixing, dispersing, homogenizing and/or circu1ation of one or more ingredients contained or added to the container. The container includes a flexible baffle shaped and positioned within the container to improve mixing, particularly to improve low shear mixing. The baffle is positioned within the container so as to disrupt the vortex formed by the mixer, or prevent formation of a vortex. The baffle is shaped with both horizontal and vertical elements to enhance disruption of the vortex across the entire vessel height and provide homogeneous mixing throughout all operating volumes. In certain embodiments, the baffle is X- shaped.

    Abstract translation: 一个容器，例如一次性或单次使用的生物反应器，任选地具有一个或多个入口和一个或多个出口以及与容器相关联的混合器，以使包含或添加的一种或多种成分混合，分散，均化和/或循环 容器 容器包括形状并定位在容器内的柔性挡板以改善混合，特别是改善低剪切混合。 挡板位于容器内，以便破坏由混合器形成的涡流，或防止形成涡流。 挡板被成形为具有水平和垂直元件，以增强跨越整个容器高度的涡流的破坏，并在整个操作体积中提供均匀的混合。 在某些实施例中，挡板是X形的。

    2D LOW LEVEL MIXING BAG FOR STORAGE AND SHIPPING
    98.
    发明申请
    2D LOW LEVEL MIXING BAG FOR STORAGE AND SHIPPING 审中-公开
    2D低水平混合袋用于存储和运输

    公开(公告)号：WO2014085035A2

    公开(公告)日：2014-06-05

    申请号：PCT/US2013/068375

    申请日：2013-11-05

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： MORRISSEY, Martin ,  PEREIRA, Brian

    IPC: B01F3/12

    CPC classification number: B01F15/0085 ,  B01F7/00241 ,  B01F13/0827 ,  B01F15/00487 ,  B01F2215/0034 ,  B01F2215/0073 ,  C12M23/14 ,  C12M27/02

    Abstract: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.

    Abstract translation: 用于流体的一次性容器，例如可变形袋，具有一个或多个入口和一个或多个出口以及容器内的叶轮组件，用于引起包含或添加的一种或多种成分的混合，分散，均化和/或循环 到容器 容器内可容纳液体的区域是漏斗形的，其允许非常低的液面混合，分配同时混合，以及减少或消除涡流形成。

    DISPENSER FOR OPENING A TAPE-LIKE PACKAGING
    100.
    发明申请
    DISPENSER FOR OPENING A TAPE-LIKE PACKAGING 审中-公开
    打开胶带包装的分配器

    公开(公告)号：WO2013101445A1

    公开(公告)日：2013-07-04

    申请号：PCT/US2012/068752

    申请日：2012-12-10

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： GUEDON, Pierre ,  JELLIMAN, Jeremy

    IPC: B65H37/04 ,  B65B33/00 ,  B65H35/07

    CPC classification number: A61F15/002 ,  B65D75/42 ,  B65D83/0463

    Abstract: A dispenser (100) for opening a tape like packaging (1), which tape like packaging comprises first and second films (10,11) releasably connected to each other and forming envelopes respectively sealed around an object (9) and disposed sequentially with a predetermined pitch. The dispenser comprises a space (3) for holding a container (2) of the tape like packaging (1), guide elements (6, 7, 8, 12, 13, 14, 15, 17, 18) for spreading apart and separating the first and second films (10,11) at an outlet of a separator (6, 7) trough which the tape like packaging (1) can be passed, when a pulling force is acting on the first and second films (10,11), thereby opening the envelopes and releasing the objects (9) contained therein, and for guiding the separated films. A receiver element (16) is provided that is rotatably supported and that is adapted to releasably hold and simultaneously wind up both the separated first and second films of the tape like packaging (1), thereby imparting the pulling force on the films (10,11), and a drive unit is provided for rotating the receiver element (16). The provision of the common receiver element to releasably hold and simultaneously wind up both separated films considerably reduces the complexity of the mechanical drive system, and facilitates the loading and unloading of the films.

    Abstract translation: 一种用于打开带状包装（1）的分配器（100），该带状包装包括彼此可释放地连接的第一和第二膜（10,11），并且形成分别围绕物体（9）密封并依次设置 预定间距。 分配器包括用于保持带状包装（1）的容器（2）的空间（3），用于分散和分离的引导元件（6,7,8,12,13,14,15,17,18） 当拉力作用在第一和第二膜（10,11）上时，分隔件（6,7）的出口处的带状包装（1）可以通过的第一和第二膜（10,11） ），从而打开信封并释放其中包含的物体（9），并引导分离的膜。 提供了可旋转地支撑并且适于可释放地保持并同时卷绕带状包装（1）的分离的第一和第二膜的接收器元件（16），从而将膜施加到膜（10， 11），并且提供驱动单元以旋转接收器元件（16）。 提供公共接收器元件以可释放地保持和同时卷绕两个分离的膜显着地降低了机械驱动系统的复杂性，并且有利于膜的装载和卸载。

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