公开(公告)号：KR101296209B1

公开(公告)日：2013-08-20

申请号：KR1020120081945

申请日：2012-07-26

Applicant: 대한민국(농촌진흥청장) ,  경북대학교 산학협력단

Inventor： 한상익 ,  장기창 ,  서우덕 ,  나지은 ,  오성환 ,  최경진 ,  강항원 ,  남민희 ,  염정현 ,  현재민

IPC: D01F1/10 ,  D01F4/00 ,  D01D1/02 ,  D01D5/00 ,  A61K8/02 ,  A61K8/64 ,  A45D44/22 ,  A61K8/34

CPC classification number: D01F1/103 ,  A45D44/22 ,  A61K8/0212 ,  A61K8/347 ,  A61K8/64 ,  D01D1/02 ,  D01D5/0015 ,  D01F4/00

Abstract: PURPOSE: Zein nanofiber which contains sorghum extract is provided to show high antibiosis and be used in the field of medical treatment and beauty treatment due to no cytotoxicity. CONSTITUTION: A manufacturing method of Zein nanofiber that has wrinkled nanofiber surface containing sorghum extract to improve heat-resisting and antibiotic comprises the manufacturing step of spinning solution and a step of electric radiation. The step of manufacturing spinning solution manufactures the blend solution by dissolving Zein which is a native protein extracted from corns, sorghum, and the sorghum byproduct extract in the solution. The electric radiation step electrically radiates the spinning solution. The extract of the sorghum or the sorghum byproduct is characterized as being the golden Sorghum bicolor L. Moench extract. The sorghum byproduct extract is characterized as being the golden sorghum stem extract and the golden sorghum leaf extract. The component of the sorghum extract and the sorghum byproduct extract is chemical formula 1 or chemical formula 2. Mask sheet which has non-uniform nanofiber surface for improving heat resistance and antibiotic comprises Zein nanofiber which contains sorghum extract manufactured by the electric radiation on the top portion of the nonwoven fabric of the mask sheet.

Abstract translation: 目的：提供含有高粱提取物的Zein纳米纤维，以显示高抗菌性，并且由于没有细胞毒性而用于医疗和美容治疗领域。 构成：含有高粱提取物的纳米纤维表面起皱以提高耐热性和抗生素的Zein纳米纤维的制造方法包括纺丝溶液的制造步骤和电辐射步骤。 制造纺丝溶液的步骤通过将玉米，高粱和高粱副产物提取物中提取的天然蛋白质的Zein溶解在溶液中来制造混合溶液。 电辐射步骤电纺丝纺丝溶液。 高粱或高粱副产品的提取物的特征在于是金色高粱双色L.Moench提取物。 高粱副产品提取物的特征是金高粱茎提取物和金黄高粱叶提取物。 高粱提取物和高粱副产物提取物的组分是化学式1或化学式2.具有不均匀纳米纤维表面以提高耐热性和抗生素的掩模片包括含有通过顶部电辐射制造的高粱提取物的玉米素纳米纤维 掩模片无纺布的一部分。

公开(公告)号：KR1020130076558A

公开(公告)日：2013-07-08

申请号：KR1020110145189

申请日：2011-12-28

Applicant: 대한민국(농촌진흥청장)

Inventor： 나지은 ,  서우덕 ,  장기창 ,  한상익 ,  최경진 ,  강항원 ,  오성환 ,  김상열

IPC: A61K36/899 ,  A61K31/37 ,  A61K31/35 ,  A61P31/12

CPC classification number: A61K31/352 ,  A61K36/899 ,  A61K2236/33

Abstract: PURPOSE: A composition containing a natural pigment extract of sorghum or polyphenol compounds such as apigenin, apigeninidine, luteolin, and luteolinidine is provided to suppress neuraminidase activity, and to be used as a pharmaceutical product, a food additive, or a feed additive with antibacterial or antiviral activity. CONSTITUTION: A pharmaceutical composition as an antibacterial agent or an antiviral agent contains a natural pigment extract of sorghum and suppresses neuraminidase. The pharmaceutical composition contains one or more kinds of polyphenol compounds selected among apigenin of chemical formula 1, apigeninidine of chemical formula 2, luteolin of chemical formula 3, and luteolinidine of chemical formula 4. A food additive with antibacterial or antiviral activity contains the one or more kinds of polyphenol compounds as active ingredients. A method for preparing the extract comprises the step of extracting sorghum powder with a methanol solvent containing 0.1-1% of hydrochloric acid at 5-40 deg. C.

Abstract translation: 目的：提供含有高粱或多酚化合物的天然色素提取物如芹菜素，芹菜碱，木犀草素和黄嘌呤苷的组合物以抑制神经氨酸酶活性，并用作药物产品，食品添加剂或具有抗菌性的饲料添加剂 或抗病毒活性。 构成：作为抗菌剂或抗病毒剂的药物组合物含有高粱的天然色素提取物，抑制神经氨酸酶。 药物组合物含有选自化学式1的芹菜素，化学式2的芹菜碱，化学式3的木犀草素和化学式4的木犀草素的一种或多种多酚化合物。具有抗菌或抗病毒活性的食品添加剂包含一种或多种 多种多酚化合物作为活性成分。 制备提取物的方法包括在5-40度下用含0.1-1％盐酸的甲醇溶剂萃取高粱粉的步骤。 C。

公开(公告)号：KR101183981B1

公开(公告)日：2012-09-27

申请号：KR1020100099133

申请日：2010-10-12

Applicant: 대한민국(농촌진흥청장)

Inventor： 한상익 ,  장기창 ,  서우덕 ,  강항원 ,  박동수 ,  이기환 ,  박수권 ,  김상민 ,  송유천 ,  이학동

IPC: A23L2/38 ,  A23L2/72 ,  A23L33/00

Abstract: 본 발명은 흑찰거대배아미 추출물을 유효성분으로 함유하는 항산화 활성 증진용 식음료 조성물, 상기 식음료 조성물의 제조방법 및 상기 식음료 조성물을 함유한 식품에 관한 것이다.

公开(公告)号：KR1020120102473A

公开(公告)日：2012-09-18

申请号：KR1020110020660

申请日：2011-03-08

Applicant: 대한민국(농촌진흥청장)

Inventor： 장기창 ,  한상익 ,  서우덕 ,  나지은 ,  오성환 ,  최경진 ,  강항원 ,  하태정

IPC: A61K36/8998 ,  A61K31/37 ,  A61P31/16 ,  A61P31/00

CPC classification number: A61K31/352 ,  A61K36/8998 ,  A61K2236/333 ,  A61K2236/55 ,  Y10S514/888

Abstract: PURPOSE: A polyphenol compound and young barley leaf extract with an effect of suppressing neuraminidase is provided to release generated virus into the outside of cells and to strongly suppress neuraminidase. CONSTITUTION: A pharmaceutical composition for preventing or treating influenza virus contains young barley leaf extract as an active ingredient and suppresses neuraminidase. The pharmaceutical composition contains a compound selected from compounds of chemical formulas 1-7. The extract is prepared using alcohol of 1-4 carbon atoms. The young barley is prepared by harvesting buds 5-15 days after sprouting and freeze-drying. A pharmaceutical composition for preventing or treating influenza virus contains the compound.

Abstract translation: 目的：提供具有抑制神经氨酸酶作用的多酚化合物和年轻大麦叶提取物，将产生的病毒释放到细胞外，强烈抑制神经氨酸酶。 构成：用于预防或治疗流感病毒的药物组合物含有年轻的大麦叶提取物作为活性成分并抑制神经氨酸酶。 药物组合物含有选自化学式1-7的化合物的化合物。 提取物是使用1-4个碳原子的醇制备的。 幼芽通过在发芽和冷冻干燥后5-15天收获芽来制备。 用于预防或治疗流感病毒的药物组合物含有该化合物。

公开(公告)号：KR102080837B1

公开(公告)日：2020-02-24

申请号：KR1020170149803

申请日：2017-11-10

Applicant: 대한민국(농촌진흥청장)

Inventor： 이미자 ,  김양길 ,  김현영 ,  서우덕 ,  강현중 ,  장기창 ,  김선림 ,  박기도

IPC: A23F5/44 ,  A23F5/36 ,  A23F5/02

公开(公告)号：KR102010858B1

公开(公告)日：2019-08-16

申请号：KR1020170124332

申请日：2017-09-26

Applicant: 대한민국(농촌진흥청장)

Inventor： 서우덕 ,  김선림 ,  강현중 ,  이미자 ,  장기창 ,  김현영 ,  박기도

IPC: A61K36/48 ,  A23L33/105

公开(公告)号：KR1020180082400A

公开(公告)日：2018-07-18

申请号：KR1020180080039

申请日：2018-07-10

Applicant: 대한민국(농촌진흥청장)

Inventor： 서우덕 ,  강현중 ,  이미자 ,  김현영 ,  김선림

IPC: A61K36/48 ,  A61K31/7048 ,  A23L33/105

CPC classification number: A61K36/48 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/306 ,  A23V2250/60 ,  A61K31/7048

Abstract: 본발명은콩 발아배아추출물을포함하는골다공증의예방또는치료용약학조성물에관한것으로, 구체적으로콩 발아배아추출물또는이의분획물을포함하는골다공증의예방또는치료용약학조성물, 상기조성물을인간을제외한개체에투여하는단계를포함하는골다공증의예방또는치료방법, 콩발아배아추출물또는이의분획물을포함하는골다공증의예방또는개선용식품조성물, 및사료조성물에관한것이다. 본발명의콩 발아배아추출물은조골세포의증식능및 분화능을향상시키며, 골밀도, 골부피및 골세포의수를증가시키는효과를나타내므로, 골다공증의예방또는치료에유용하게사용될수 있다.

公开(公告)号：KR101847117B1

公开(公告)日：2018-04-11

申请号：KR1020160082665

申请日：2016-06-30

Applicant: 대한민국(농촌진흥청장) ,  진도군

Inventor： 조준현 ,  송유천 ,  서우덕 ,  이지윤 ,  손영보 ,  신동진 ,  한상익 ,  박동수 ,  권영업 ,  정재선 ,  박야영 ,  장병인 ,  김영남 ,  박성철 ,  오영애 ,  박종일

IPC: A01H5/10 ,  A01H1/02 ,  A01G9/00

Abstract: 본발명은안토시아닌고함유신품종벼, 밀양227호와조생흑찰벼를인공교배하는단계를포함하는상기안토시아닌고함유신품종벼의육종방법및 상기신품종벼를재배하는단계를포함하는안토시아닌의함량이증가된벼의재배방법에관한것이다. 본발명의신품종벼는항산화활성이높은기능성물질안토시아닌의함량이조생흑찰에비하여 2.5배정도높아혼반등의건강식으로매우활용성이높고, 흑미초콜릿제조등의다양한기능성식품가공에도유용하게활용될수 있다.

公开(公告)号：KR101820096B1

公开(公告)日：2018-02-28

申请号：KR1020160078784

申请日：2016-06-23

Applicant: 대한민국(농촌진흥청장)

Inventor： 서우덕 ,  강현중 ,  이미자 ,  김선림

IPC: A61K36/48 ,  A61K31/704 ,  A23L1/30 ,  A23K10/30

Abstract: 본발명은콩 발아배아추출물또는이의분획물을포함하는대사성질환의예방또는치료용약학조성물, 상기조성물을인간을제외한개체에투여하는단계를포함하는대사성질환의예방또는치료방법, 콩발아배아추출물또는이의분획물을포함하는대사성질환의예방또는개선용식품조성물, 및사료조성물에관한것이다. 본발명의콩 발아배아추출물은 HDL을증가시키는지질대사에관여함으로써생체내 불필요한콜레스테롤을제거하므로, 지질대사의이상에의해발병하는대사성질환의예방또는치료에유용하게사용될수 있다.

公开(公告)号：KR101822393B1

公开(公告)日：2018-01-26

申请号：KR1020160146059

申请日：2016-11-03

Applicant: 대한민국(농촌진흥청장)

Inventor： 서우덕 ,  강현중 ,  이미자 ,  송득영 ,  박기도

IPC: A61K31/704 ,  A61K36/48 ,  A23L33/10 ,  A23L33/105

CPC classification number: A61K31/704 ,  A23L33/10 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/306 ,  A23V2250/21 ,  A61K36/48

Abstract: 본발명은새싹땅콩추출물로부터분리된소야사포닌Ⅰ 또는이의약학적으로허용되는염을포함하는골다공증예방또는치료용약학조성물, 상기약학조성물을인간을제외한개체에투여하는단계를포함하는골다공증예방또는치료방법, 상기소야사포닌Ⅰ 또는이의약학적으로허용되는염을포함하는식품조성물및 사료조성물에관한것이다. 본발명에서제공하는소야사포닌Ⅰ 또는이의약학적으로허용되는염을포함하는약학조성물은부작용이없으면서골다공증의증상을치료또는개선시킬수 있으므로, 다양한형태의골다공증치료용제제의개발에널리활용될수 있을것이다.

Abstract translation: 本发明的骨质疏松症预防或治疗包括向所述大豆皂苷Ⅰ或u​​iyakhak敌人药物骨质疏松症的预防或治疗盐可接受的组合物施用，所述药物组合物从发芽的花生分离提取除人以外的对象 大豆皂角苷I或其药学上可接受的盐对食品组合物和饲料组合物的用途。 包含大豆皂苷Ⅰ或可接受的盐的药物组合物被uiyakhak有史以来本发明所提供的，因为副作用eopeumyeonseo sikilsu治疗或改善骨质疏松症的症状，它将被广泛用于各种形式的骨质疏松溶剂要约的发展。