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公开(公告)号:DE10359661A1
公开(公告)日:2005-07-28
申请号:DE10359661
申请日:2003-12-18
Applicant: BASF AG
Inventor: KLOPPROGGE CORINNA , ZELDER OSKAR , KROEGER BURKHARD , SCHROEDER HARTWIG , HAEFNER STEFAN , RUFFER UWE , GRAEF CLAUDIA ISABELLA , HABERHAUER GREGOR
IPC: C07K14/34 , C07K14/195 , C12N15/31
Abstract: The present invention relates to mutated nucleic acids and proteins of the metabolic pathway of fine chemicals, to processes for preparing genetically modified producer organisms, to processes for preparing fine chemicals by culturing genetically modified organisms, and to genetically modified organisms themselves.
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公开(公告)号:ZA200404424B
公开(公告)日:2005-06-06
申请号:ZA200404424
申请日:2004-06-04
Applicant: BASF AG
Inventor: ZELDER OSKAR , POMPEJUS MARKUS , SCHROEDER HARTWIG , KROEGER BURKHARD , KLOPPROGGE CORINNA , HABERHAUER GREGOR
Abstract: Isolated nucleic acid (I) that encodes any of 50 amino acid sequences (II) that have, at specific positions, an amino acid (aa) alteration. The specification includes (i) a table identifying the function of (II) and the nature/position of the amino acid exchange and (ii) sequences for (I) and (II). Independent claims are also included for the following: (1) vector that contains at least one (I); (2) host cell transfected with at least one vector of component (1); and (3) preparing fine chemicals by culturing cells of component (2).
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93.
公开(公告)号:ZA200200585B
公开(公告)日:2004-10-27
申请号:ZA200200585
申请日:2002-01-23
Applicant: BASF AG
Inventor: HABERHAUER GREGOR , KROEGER BURKHARD , POMPEJUS MARKUS , SCHROEDER HARTWIG , ZELDER OSKAR
IPC: C07K20060101 , C12N20060101 , C12P20060101 , C12Q20060101 , C12N , C07K
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公开(公告)号:DE10217058A1
公开(公告)日:2003-11-27
申请号:DE10217058
申请日:2002-04-17
Applicant: BASF AG
Inventor: KROEGER BURKHARD , ZELDER OSKAR , KLOPPROGGE CORINNA , SCHROEDER HARTWIG , HAEFNER STEFAN
Abstract: The invention relates to methods for the fermentative production of sulfur-containing fine chemicals, in particular L-methionine, by using bacteria which express a nucleotide sequence coding for a methionine synthase (metH) gene.
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公开(公告)号:DE10154177A1
公开(公告)日:2003-05-08
申请号:DE10154177
申请日:2001-11-05
Applicant: BASF AG
Inventor: ZELDER OSKAR , POMPEJUS MARKUS , SCHROEDER HARTWIG , KROEGER BURKHARD , KLOPPROGGE CORINNA , HABERHAUER GREGOR
Abstract: Isolated nucleic acid (I) that encodes particular protein sequences (II) that have, at specific positions, an amino acid alteration. Independent claims are also included for: (1) Vector that contains at least one (I); (2) Host cell transfected with at least one vector of (1); and (3) Method for preparing fine chemicals by culturing cells of (2).
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公开(公告)号:CA2457807A1
公开(公告)日:2003-03-06
申请号:CA2457807
申请日:2002-08-23
Applicant: BASF AG
Inventor: REVUELTA DOVAL JOSE L , KAROS MARVIN , KROEGER BURKHARD , ALTHOEFER HENNING
IPC: C12N15/09 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N15/31 , C12P25/00 , C12Q1/68 , C12N15/52 , C12Q1/25 , C12N15/81
Abstract: The invention relates to novel polynucleotides of Ashbya gossypii; oligonucleotides hybridizing therewith; expression cassettes and vectors containing said polynucleotides; microorganisms transformed therewith; polypetides coded by said polynucleotides; and the use of the novel polypeptides and polynucleotides as targets in the modulation of metabolism reactions and especially in order to improve vitamin B2 production in microorganisms of the genus Ashbya.
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97.
公开(公告)号:HU0203647A2
公开(公告)日:2003-01-28
申请号:HU0203647
申请日:2000-06-23
Applicant: BASF AG
Inventor: HABERHAUER GREGOR , KROEGER BURKHARD , POMPEJUS MARKUS , SCHROEDER HARTWIG , ZELDER OSKAR
IPC: C12N15/09 , C07K20060101 , C07K14/34 , C12N20060101 , C12N1/21 , C12N9/00 , C12N9/02 , C12N9/18 , C12N15/31 , C12N15/52 , C12P20060101 , C12P13/04 , C12P21/02 , C12Q20060101 , C12R1/15
Abstract: Isolated nucleic acid molecules, designated HA nucleic acid molecules, which encode novel HA proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing HA nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated HA proteins, mutated HA proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of HA genes in this organism.
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公开(公告)号:ES2174768T1
公开(公告)日:2002-11-16
申请号:ES00942322
申请日:2000-06-27
Applicant: BASF AG
Inventor: POMPEJUS MARKUS , KROEGER BURKHARD , SCHROEDER HARTWIG , ZELDER OSKAR , HABERHAUER GREGOR
IPC: G01N33/53 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/10 , C12N9/12 , C12N15/09 , C12N15/31 , C12N15/54 , C12P1/04 , C12P13/04 , C12Q1/04 , C12Q1/68 , C12R1/13 , C12R1/16 , G01N33/566 , G01N33/569 , C12N15/77
Abstract: Isolated nucleic acid molecules, designated PTS nucleic acid molecules, which encode novel PTS proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PTS nucleic acid molecules, and host cells into which expression vectors have been introduced. The invention still further provides isolated PTS proteins, mutated PTS proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. Glutamicum based on genetic engineering of PTS genes in this organism.
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99.
公开(公告)号:CZ20014659A3
公开(公告)日:2002-09-11
申请号:CZ20014659
申请日:2000-06-23
Applicant: BASF AG
Inventor: POMPEJUS MARKUS , KROEGER BURKHARD , SCHROEDER HARTWIG , ZELDER OSKAR , HABERHAUER GREGOR
IPC: G01N33/53 , C07K20060101 , C07K14/34 , C12N20060101 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/12 , C12N9/18 , C12N9/88 , C12N15/09 , C12N15/31 , C12N15/55 , C12P20060101 , C12P13/04 , C12P13/08 , C12P21/02 , C12Q20060101 , C12Q1/68 , C12R1/15 , G01N33/566 , G01N33/569
Abstract: Isolated nucleic acid molecules, designated SMP nucleic acid molecules, which encode novel SMP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SMP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SMP proteins, mutated SMP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of SMP genes in this organism.
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100.
公开(公告)号:SK18892001A3
公开(公告)日:2002-09-10
申请号:SK18892001
申请日:2000-06-27
Applicant: BASF AG
Inventor: POMPEJUS MARKUS , KROEGER BURKHARD , SCHROEDER HARTWIG , ZELDER OSKAR , HABERHAUER GREGOR
IPC: G01N33/53 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/10 , C12N9/12 , C12N15/09 , C12N15/31 , C12N15/54 , C12P1/04 , C12P13/04 , C12Q1/04 , C12Q1/68 , C12R1/13 , C12R1/16 , G01N33/566 , G01N33/569 , C12N15/77
Abstract: Isolated nucleic acid molecules, designated PTS nucleic acid molecules, which encode novel PTS proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PTS nucleic acid molecules, and host cells into which expression vectors have been introduced. The invention still further provides isolated PTS proteins, mutated PTS proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. Glutamicum based on genetic engineering of PTS genes in this organism.
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