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公开(公告)号：DE69527923T2
公开(公告)日：2003-04-24
申请号：DE69527923
申请日：1995-05-25
Applicant: BAXTER INT
Inventor： MARTIS LEO , HENDERSON W
IPC: A61K9/08 , A61K31/19 , A61K31/194 , A61K31/70 , A61K31/7004 , A61K33/00 , A61K33/10 , A61K33/14 , A61M1/28 , A61P7/08 , A61P13/12 , A61M1/16
Abstract: A peritoneal dialysis solution that is biochemically balanced to correct metabolic acidosis associated with chronic renal failure in a more physiological manner. The peritoneal dialysis solution has a physiological pH, e.g. pH of 70 to 74 and contains bicarbonate at a concentration that is found in normal blood. Additionally, the solution contains carbon dioxide at a partial pressure that is similar to partial pressure of carbon dioxide found in normal blood. The peritoneal dialysis solution also contains a weak acid with a pKa of less than 5.0.
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公开(公告)号：DE69527660T2
公开(公告)日：2003-04-03
申请号：DE69527660
申请日：1995-01-23
Applicant: BAXTER INT
Inventor： MARTIS LEO , SHOCKLEY TY , BURKE RON , HENDERSON LEE W , FALLER BERNARDETTE
IPC: A61K31/715 , A61M1/14 , A61K33/14 , A61M1/28
Abstract: The method relates to providing an osmotic agent for a peritoneal dialysis solution containing sodium chloride and optionally lactate, bicarbonate, calcium and magnesium ions. The osmotic agent added comprises a first composition with a weight average molecular weight of ≥ 10,000 daltons and 0.25 to 2.0 (% w/v) of a second composition with a weight average molecular weight of ≤ 300 daltons.
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公开(公告)号：ES2181117T3
公开(公告)日：2003-02-16
申请号：ES98200026
申请日：1995-01-23
Applicant: BAXTER INT
Inventor： MARTIS LEO , SHOCKLEY TY , BURKE RON , HENDERSON LEE W , FALLER BERNARDETTE
IPC: A61K31/715 , A61K33/14 , A61M1/28 , A61M1/14
Abstract: The method relates to providing an osmotic agent for a peritoneal dialysis solution containing sodium chloride and optionally lactate, bicarbonate, calcium and magnesium ions. The osmotic agent added comprises a first composition with a weight average molecular weight of ≥ 10,000 daltons and 0.25 to 2.0 (% w/v) of a second composition with a weight average molecular weight of ≤ 300 daltons.
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公开(公告)号：DE69332433D1
公开(公告)日：2002-11-28
申请号：DE69332433
申请日：1993-12-10
Applicant: BAXTER INT
Inventor： MARTIS LEO , JONES MICHAEL R
IPC: A61K31/195 , A61K31/198 , A61K31/40 , A61K31/405 , A61K31/415 , A61K33/10 , A61K33/14 , A61M1/28 , A61P13/00 , A61P13/02 , A61P15/00 , A61K9/08 , A23J1/14
Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.
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公开(公告)号：AT226433T
公开(公告)日：2002-11-15
申请号：AT94903603
申请日：1993-12-10
Applicant: BAXTER INT
Inventor： MARTIS LEO , JONES MICHAEL R
IPC: A61K31/195 , A61K31/198 , A61K31/40 , A61K31/405 , A61K31/415 , A61K33/10 , A61K33/14 , A61M1/28 , A61P13/00 , A61P13/02 , A61P15/00 , A61K9/08 , A61P3/00
Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.
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Patent Agency Ranking
公开(公告)号：CO5200780A1
公开(公告)日：2002-09-27
申请号：CO00061540
申请日：2000-08-16
Applicant: BAXTER INT
Inventor： DUPONCHELLE ANNICK , FAICT DIRK , BALTEAU PATRICK , HARTMAN JEAN-PIERRE , MARTIS LEO , PELUSO FRANCESCO
IPC: A61J3/00 , A61J1/05 , A61J1/10 , A61J1/20 , A61K9/08 , A61K33/10 , A61K33/14 , A61M1/14 , A61M1/16 , A61M1/28 , A61P13/12
Abstract: Una solución en dos partes que contiene bicarbonato, la solución comprende:Una primer parte contenida en un primer contenedor, la primer parte incluye un concentrado de bicarbonato alcalino que tiene un pH que varía desde aproximadamente 8,6 a 10,0;Una segunda parte contenida en un segundo contenedor, la segunda parte incluye un concentrado ácido que tiene un pH que varía desde aproximadamente 1,0 a 3,0, el pH del concentrado ha sido efectivo para obtener, cuando la primer parte y la segunda parte se mezclan, una solución mezclada que tiene un pH que varia desde 6,5 a 7,6.
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公开(公告)号：HK1041653A1
公开(公告)日：2002-07-19
申请号：HK02103534
申请日：2002-05-09
Applicant: BAXTER INT
Inventor： DUPONCHELLE ANNICK , FAICT DIRK , BALTEAU PATRICK , HARTMAN JEAN-PIERRE , MARTIS LEO , PELUSO FRANCESCO
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公开(公告)号：ES2157523T3
公开(公告)日：2001-08-16
申请号：ES97203411
申请日：1993-12-10
Applicant: BAXTER INT
Inventor： MARTIS LEO , FAICT DIRK , BURKE RON
IPC: A61K31/70 , A61K33/00 , A61K9/08 , A61K38/00 , A61K38/01 , A61K38/02 , A61K47/26 , A61K47/42 , A61M1/14 , A61M1/28 , A61P7/08 , A61M1/18
Abstract: The solution contains as osmotic agents both dectrose and polypeptides. The polypeptides are synthetic and are 4 to 10 amino acids long.
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公开(公告)号：SG66209A1
公开(公告)日：1999-07-20
申请号：SG1995002033
申请日：1995-01-23
Applicant: BAXTER INT
Inventor： MARTIS LEO , BURKE RON , SHOCKLEY TY , HENDERSON LEE W , FALLER BERNARDETTE
IPC: A61K31/715 , A61K33/14 , A61M1/28 , A61M1/14 , A61K31/195 , A61K9/08
Abstract: The method relates to providing an osmotic agent for a peritoneal dialysis solution containing sodium chloride and optionally lactate, bicarbonate, calcium and magnesium ions. The osmotic agent added comprises a first composition with a weight average molecular weight of ≥ 10,000 daltons and 0.25 to 2.0 (% w/v) of a second composition with a weight average molecular weight of ≤ 300 daltons.
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公开(公告)号：DE69319583D1
公开(公告)日：1998-08-13
申请号：DE69319583
申请日：1993-12-10
Applicant: BAXTER INT
Inventor： MARTIS LEO , BURKE RON , FAICT DIRK
IPC: A61K9/08 , A61K31/70 , A61K33/00 , A61K38/00 , A61K38/01 , A61K38/02 , A61K47/26 , A61K47/42 , A61M1/14 , A61M1/28 , A61P7/08
Abstract: The solution contains as osmotic agents both dectrose and polypeptides. The polypeptides are synthetic and are 4 to 10 amino acids long.
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