公开(公告)号：FI871081A0

公开(公告)日：1987-03-12

申请号：FI871081

申请日：1987-03-12

Applicant: HOECHST AG

Inventor： BLUME ERNST ,  SCHAPER WOLFGANG ,  EHRHARDT HEINZ ,  RAETHER WOLFGANG ,  DITTMAR WALTER ,  HAENEL HEINZ ,  SACHSE BURKHARD

IPC: C07D247/00 ,  A01N43/50 ,  A01N43/653 ,  C07C41/00 ,  C07C43/18 ,  C07C67/00 ,  C07C201/00 ,  C07C213/00 ,  C07C215/42 ,  C07C217/48 ,  C07C217/74 ,  C07C253/00 ,  C07C255/54 ,  C07C313/00 ,  C07C317/12 ,  C07C317/14 ,  C07C317/18 ,  C07C317/20 ,  C07C323/22 ,  C07D233/56 ,  C07D233/60 ,  C07D233/61 ,  C07D249/08 ,  C07D307/38 ,  C07D333/00 ,  C07D401/12 ,  C07D403/12 ,  C07D405/06 ,  C07D405/12 ,  C07D409/12 ,  C07D409/14 ,  C07D417/12 ,  C07D521/00 ,  C07D

Abstract: Compounds I I where A equals t-butyl or a large number of (substituted) aromatics; Y equals azolyl; or Y equals -X-R1 where X=oxygen or sulfur and R1 equals (cyclo)alkyl or (heterocyclic) aryl; or Y equals where R2 equals (cyclo)alkyl, acetyl or aryl; or Y equals -NR3R4 where R3/R4 is alkyl; or Y equals several nitrogen-containing heterocyclic rings; Z equals OH, alkylcarbonyloxy, hal, alkoxy or benzyloxy; and the salts thereof are effective antimycotics or fungicides. They are obtained by reaction of II II with (CH3)2 III and further reaction of the compound IV obtained from this with a nucleophile YM (M=hydrogen or a metal equivalent). The compounds I (where Z=OH) resulting from this can be acylated or alkylated, or converted into I where Z=hal.

公开(公告)号：DE3530799A1

公开(公告)日：1987-03-05

申请号：DE3530799

申请日：1985-08-29

Applicant: HOECHST AG

Inventor： SCHAPER WOLFGANG DIPL CHEM DR ,  RAETHER WOLFGANG DR ,  DITTMAR WALTER DR ,  SACHSE BURKHARD ,  HARTZ PETER DIPL BIOL DR

IPC: C07D409/06 ,  A01N43/50 ,  A01N43/653 ,  A61K31/41 ,  A61K31/415 ,  A61P31/00 ,  A61P31/04 ,  C07D233/60 ,  C07D249/08 ,  C07D333/00 ,  C07D409/08 ,  C07D521/00 ,  C07D401/06 ,  C07D405/06 ,  C07D401/08 ,  C07D405/08

Abstract: Azole derivatives of the formula I where A equals CH or N and R /R equals substituted or unsubstituted phenyl, biphenylyl, phenoxyphenyl, benzylphenyl, benzyloxyphenyl, naphthyl, thienyl, furyl or pyridyl and their salts and esters have outstanding antimycotic and fungicidal activity in all stereoisomeric forms. They are obtained by reaction of a compound II with a sulphur ylide of the formula III to give the compound IV which is reacted with the corresponding compound V to give I. Compound VI can also be used as a starting material and is reacted with 2 equivalents of IIIa compound IV being formed; or compound VI is first reacted with an equivalent of IIIa to give II, and II is then reacted, without working up, with the sulphur ylide IIIb (CH3)2SCH2 to give IV and this is reacted with V to give I.

公开(公告)号：AU6203086A

公开(公告)日：1987-03-05

申请号：AU6203086

申请日：1986-08-28

Applicant: HOECHST AG

Inventor： SCHAPER WOLFGANG ,  RAETHER WOLFGANG ,  DITTMAR WALTER ,  SACHSE BURKHARD ,  HARTZ PETER

IPC: C07D409/06 ,  A01N43/50 ,  A01N43/653 ,  A61K31/41 ,  A61K31/415 ,  A61P31/00 ,  A61P31/04 ,  C07D233/60 ,  C07D249/08 ,  C07D333/00 ,  C07D409/08 ,  C07D521/00 ,  C07D401/08 ,  C07D401/06 ,  C07D405/06 ,  C07D405/08

Abstract: Azole derivatives of the formula I where A equals CH or N and R /R equals substituted or unsubstituted phenyl, biphenylyl, phenoxyphenyl, benzylphenyl, benzyloxyphenyl, naphthyl, thienyl, furyl or pyridyl and their salts and esters have outstanding antimycotic and fungicidal activity in all stereoisomeric forms. They are obtained by reaction of a compound II with a sulphur ylide of the formula III to give the compound IV which is reacted with the corresponding compound V to give I. Compound VI can also be used as a starting material and is reacted with 2 equivalents of IIIa compound IV being formed; or compound VI is first reacted with an equivalent of IIIa to give II, and II is then reacted, without working up, with the sulphur ylide IIIb (CH3)2SCH2 to give IV and this is reacted with V to give I.

公开(公告)号：DK409886A

公开(公告)日：1987-03-01

申请号：DK409886

申请日：1986-08-28

Applicant: HOECHST AG

Inventor： SCHAPER WOLFGANG ,  RAETHER WOLFGANG ,  DITTMAR WALTER ,  SACHSE BURKHARD ,  HARTZ PETER

IPC: C07D409/06 ,  A01N43/50 ,  A01N43/653 ,  A61K31/41 ,  A61K31/415 ,  A61P31/00 ,  A61P31/04 ,  C07D233/60 ,  C07D249/08 ,  C07D333/00 ,  C07D409/08 ,  C07D521/00 ,  C07D

Abstract: Azole derivatives of the formula I where A equals CH or N and R /R equals substituted or unsubstituted phenyl, biphenylyl, phenoxyphenyl, benzylphenyl, benzyloxyphenyl, naphthyl, thienyl, furyl or pyridyl and their salts and esters have outstanding antimycotic and fungicidal activity in all stereoisomeric forms. They are obtained by reaction of a compound II with a sulphur ylide of the formula III to give the compound IV which is reacted with the corresponding compound V to give I. Compound VI can also be used as a starting material and is reacted with 2 equivalents of IIIa compound IV being formed; or compound VI is first reacted with an equivalent of IIIa to give II, and II is then reacted, without working up, with the sulphur ylide IIIb (CH3)2SCH2 to give IV and this is reacted with V to give I.

公开(公告)号：PH19231A

公开(公告)日：1986-02-12

申请号：PH29780

申请日：1983-11-03

Applicant: HOECHST AG

Inventor： MAIER THOMAS ,  BURSTELL HELMUT ,  SCHMIERER ROLAND ,  BAUER KLAUS ,  BIERINGER HERMANN ,  SACHSE BURKHARD

IPC: A01N9/22

公开(公告)号：PH18564A

公开(公告)日：1985-08-09

申请号：PH27372

申请日：1982-05-31

Applicant: HOECHST AG

Inventor： HERTENSTEIN ULRICH ,  MILDENBERGER HILMAR ,  SACHSE BURKHARD ,  HARTZ PETER

IPC: A01N43/653 ,  A01P3/00 ,  A61K31/41 ,  A61K31/415 ,  C07D231/12 ,  C07D233/56 ,  C07D233/58 ,  C07D233/60 ,  C07D233/64 ,  C07D233/68 ,  C07D233/91 ,  C07D235/06 ,  C07D249/08 ,  C07D521/00 ,  C07D235/04

Abstract: Substituted ethanols of the general formula in which Ar1 is a carbocyclic or heterocyclic ring and Az is a triazolyl, benzimidazolyl, pyrazolyl or imidazolyl radical, are reacted with aryl hydrocarbons Ar2-H, in which Ar2 has the same meaning as Ar1, in the presence of an acidic catalyst, to give 1,1-diaryl-2-azolylethanes. The substances, which, apart from the imidazolyl derivatives, are new, can be used as biocides, in particular fungicides.

公开(公告)号：FI850266L

公开(公告)日：1985-07-24

申请号：FI850266

申请日：1985-01-21

Applicant: HOECHST AG

Inventor： SCHAPER WOLFGANG ,  BLUME ERNST ,  RAETHER WOLFGANG ,  DITTMAR WALTER ,  ALPERMANN HANS GEORG ,  SACHSE BURKHARD ,  HARTZ PETER

IPC: A01N43/50 ,  A01N43/653 ,  A61K31/41 ,  A61K31/415 ,  A61P25/00 ,  A61P25/24 ,  A61P25/26 ,  A61P31/04 ,  B27K3/38 ,  C07C45/60 ,  C07C49/84 ,  C07D233/60 ,  C07D249/08 ,  C07D295/096 ,  C07D295/185 ,  C07D333/00 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D405/06 ,  C07D409/06 ,  C07D521/00 ,  C09D5/14 ,  C07D

Abstract: Azolyl derivatives of the formula I where A = CH or N; n = 2 - 12; Ar = aromatic; R = alkyl, alkenyl, alkynyl or benzyl; and Q = -S(O)1-3R or -OR (R = alkyl, cycloalkyl, alkenyl and some aromatics; R = saturated or unsaturated alkyl, cycloalkyl, cycloalkylalkyl, aromatics) and processes for their preparation are described. They are antimicrobial agents active against fungal infections. The intermediates of the formula VIIa have antidepressive properties.

公开(公告)号：CA1182120A

公开(公告)日：1985-02-05

申请号：CA404147

申请日：1982-05-31

Applicant: HOECHST AG

Inventor： HERTENSTEIN ULRICH ,  MILDENBERGER HILMAR ,  SACHSE BURKHARD ,  HARTZ PETER

IPC: A01N43/653 ,  A01P3/00 ,  A61K31/41 ,  A61K31/415 ,  C07D231/12 ,  C07D233/56 ,  C07D233/58 ,  C07D233/60 ,  C07D233/64 ,  C07D233/68 ,  C07D233/91 ,  C07D235/06 ,  C07D249/08 ,  C07D521/00 ,  A01N43/64

Abstract: Substituted ethanols of the general formula in which Ar1 is a carbocyclic or heterocyclic ring and Az is a triazolyl, benzimidazolyl, pyrazolyl or imidazolyl radical, are reated with aryl hydrocarbons Ar2-H, in which Ar2 has the same meaning as Ar1, in the presence of an acidic catalyst, to give 1,1-diaryl-2azolylethanes. The substances, which apart from the imidazolyl derivatives, are new, can be used as biocides, in particular fungicides.

公开(公告)号：DD212889A5

公开(公告)日：1984-08-29

申请号：DD25353583

申请日：1983-07-29

Applicant: HOECHST AG

Inventor： STAHLER GERHARD ,  KNAUF WERNER ,  SACHSE BURKHARD ,  WALTERSDORFER ANNA

IPC: A01N57/12 ,  A01N57/10 ,  A01N57/18 ,  A01N57/20 ,  A01N57/24 ,  A01N57/26 ,  A01N57/28 ,  A01N57/32 ,  C07F9/165 ,  C07F9/24 ,  C07F9/40 ,  A01N33/26

Abstract: Compounds of the formula I (I) in which R denotes alkyl, R1 denotes alkyl, alkoxy, alkylmercapto, alkylamino or dialkylamino, R2 and R3 independently of one another denote H, alkyl, cycloalkyl, benzyl or furylmethyl, R4 denotes alkyl, alkoxymethyl, alkylmercaptomethyl or phenyl and X denotes oxygen or sulfur, have valuable insecticidal, acaricidal and nematocidal properties.

公开(公告)号：DD212884A5

公开(公告)日：1984-08-29

申请号：DD25621483

申请日：1983-11-01

Applicant: HOECHST AG

Inventor： MAIER THOMAS ,  SCHMIERER ROLAND ,  BAUER KLAUS ,  BIERINGER HERMANN ,  BUERSTELL HELMUT ,  SACHSE BURKHARD

IPC: A01N43/50