公开(公告)号：JPS63166886A

公开(公告)日：1988-07-11

申请号：JP32420187

申请日：1987-12-23

Applicant: HOECHST AG

Inventor： HAMMANN PETER ,  GRABLEY SUSANNE ,  VOELSKOW HARTMUT ,  SACHSE BURKHARD ,  RAETHER WOLFGANG ,  GIANI CARLO ,  SEIBERT GERHARD

IPC: C12P17/08 ,  A01N63/02 ,  A61K20060101 ,  A61K31/365 ,  A61P31/00 ,  A61P31/10 ,  C07D313/00 ,  C07D493/04 ,  C07D493/08 ,  C12N20060101 ,  C12P20060101 ,  C12P1/02 ,  C12P17/18 ,  C12R1/465

公开(公告)号：DE59104720D1

公开(公告)日：1995-03-30

申请号：DE59104720

申请日：1991-06-12

Applicant: HOECHST AG

Inventor： ULBRICH NORBERT ,  HILGENFELD ROLF ,  HAENEL HEINZ ,  SACHSE BURKHARD ,  BRAUN PETER ,  WINK JOACHIM ,  ECKES PETER ,  LOGEMANN JUERGEN ,  SCHELL JOZEF

IPC: A01H5/00 ,  A01N63/00 ,  A01N63/04 ,  A61K38/00 ,  C07K14/00 ,  C07K14/195 ,  C07K14/37 ,  C07K14/41 ,  C07K14/415 ,  C12N5/10 ,  C12N15/09 ,  C12N15/31 ,  C12N15/82 ,  C12P21/02 ,  C12R1/66

Abstract: The polypeptide with the sequence (SEQ ID NO: 1) - Ala-Thr-Tyr-Asn-Gly-Lys-Cys-Tyr-Lys-Lys-Asp- - Asn-Ile-Cys-Lys-Tyr-Lys-Ala-Gln-Ser-Gly-Lys- - Thr-Ala-Ile-Cys-Lys-Cys-Tyr-Val-Lys-Lys-Cys- - Pro-Arg-Asp-Gly-Ala-Lys-Cys-Glu-Phe-Asp-Ser- - Tyr-Lys-Gly-Lys-Cys-Tyr-Cys - can be produced by the fermentation of Aspergillus giganteus and used as an antifungal agent. Expression of this polypeptide gene in plants strongly inhibits the growth of phytopathogenic fungi on the plant.

公开(公告)号：CA1334196C

公开(公告)日：1995-01-31

申请号：CA518739

申请日：1986-09-22

Applicant: HOECHST AG

Inventor： SIEGEL HERBERT ,  KAMPE KLAUS-DIETER ,  ALPERMANN HANS G ,  GERHARDS HERMANN J ,  USINGER PATRICIA ,  SCHACHT ULRICH ,  LEVEN MARGRET ,  RAETHER WOLFGANG ,  DITTMAR WALTER ,  SACHSE BURKHARD

IPC: A61K31/41 ,  A61K31/415 ,  C07D233/60 ,  C07D233/64 ,  C07D249/08 ,  C07D521/00 ,  C07D233/56 ,  C07D405/06

Abstract: Arylmethylazoles of the formula I in which Aryl is (substituted) phenyl or naphthyl; Z is CH or N; R1 and Q are H or alkyl; R2 is H, alk(en)yl or alkynyl; R3 and R4 are H, alkyl or other hydrocarbons; or R3 and R4 together are a -(CH2)2-11 chain or a bridged -(CH2)4-5 chain, and their acid addition salts, stereoisomers and optically active enantiomers possess outstanding antimycotic and antidepressant activity. The compounds of the Formula I are obtained, inter alia, from arylmethylazoles II II which are reacted with a strong base and then with a carbonyl compound III 0=CR3R4; thereafter, the product is reacted with the protic acid or with an alkyl halide IV R2Hal. If desired, the products are converted to the acid addition salts, or the stereoisomers or optically active enantiomers are resolved.

公开(公告)号：MX9305213A

公开(公告)日：1994-05-31

申请号：MX9305213

申请日：1993-08-27

Applicant: HOECHST AG

Inventor： HEUBACH GUENTHER ,  BRAUN PETER ,  SACHSE BURKHARD

IPC: A01N43/40 ,  B27K3/34 ,  C07D211/58 ,  C09D5/14 ,  C10M133/40 ,  C07D213/90

公开(公告)号：AU649487B2

公开(公告)日：1994-05-26

申请号：AU8585991

申请日：1991-10-16

Applicant: HOECHST AG

Inventor： VERMEHREN JAN ,  GIENCKE WOLFGANG ,  BRAUN PETER ,  SACHSE BURKHARD

IPC: A01N43/54 ,  C07D401/04 ,  C07D403/04

Abstract: Pyrimidine derivatives of the formula I (I) in which the variables are herein below described in the specification. R3, R4 and R5 optionally together with the radical R3 are a component of a maximally unsaturated lambda -membered ring where lambda is 3 to 8, two radicals R6 to R9 together may form a component of an unsaturated or saturated m-membered ring where m is 5 or 6, k is 0, 1 or 2, n is 1 or 2 and the addition salts thereof, their preparation, compositions containing them, and their use in the control of harmful fungi.

公开(公告)号：ZA936308B

公开(公告)日：1994-03-25

申请号：ZA936308

申请日：1993-08-27

Applicant: HOECHST AG

Inventor： HEUBACH GUENTHER ,  BRAUN PETER ,  SACHSE BURKHARD

IPC: A01N43/40 ,  B27K3/34 ,  C07D211/58 ,  C09D5/14 ,  C10M133/40 ,  C07D ,  A01N ,  B27K ,  C09D ,  C10M

公开(公告)号：ZA9306308B

公开(公告)日：1994-03-25

申请号：ZA9306308

申请日：1993-08-27

Applicant: HOECHST AG

Inventor： HEUBACH GUENTHER ,  BRAUN PETER ,  SACHSE BURKHARD

IPC: A01N43/40 ,  B27K3/34 ,  C07D211/58 ,  C09D5/14 ,  C10M133/40 ,  C07D ,  A01N ,  B27K ,  C09D ,  C10M

CPC classification number: C10M133/40 ,  A01N43/40 ,  C07D211/58 ,  C09D5/14 ,  C10M2215/22 ,  C10M2215/221 ,  C10M2215/225 ,  C10M2215/226 ,  C10M2215/30 ,  C10N2240/40 ,  C10N2240/401

公开(公告)号：MX9301399A

公开(公告)日：1993-11-01

申请号：MX9301399

申请日：1993-03-12

Applicant: HOECHST AG

Inventor： SCHAPER WOLFGANG ,  PREUSS RAINER ,  SALBECK GISELA ,  BRAUN PETER ,  KNAUF WERNER ,  SACHSE BURKHARD ,  WALTERSDORFER ANNA ,  KERN MANFRED ,  BONIN PETER LUMMEN WERNER

IPC: A01N43/54 ,  A01N43/90 ,  A01P3/00 ,  A01P7/02 ,  A01P7/04 ,  C07D239/34 ,  C07D239/42 ,  C07D239/46 ,  C07D239/52 ,  C07D239/60 ,  C07D239/88 ,  C07D239/94 ,  C07D401/12 ,  C07D405/12 ,  C07D491/048 ,  C07D495/04 ,  C07D239/24

Abstract: The invention relates to compounds of the formula defined in the description, X is NH or oxygen and E is a bond or a 1- to 4-membered carbon chain, to a process for their preparation, to agents containing them, and to their use in the control of pests and as fungicides.

公开(公告)号：CA2131545A1

公开(公告)日：1993-09-30

申请号：CA2131545

申请日：1993-03-10

Applicant: HOECHST AG

Inventor： SCHAPER WOLFGANG ,  FREUSS RAINER ,  SALBECK GERHARD ,  BRAUN PETER ,  KNAUF WERNER ,  SACHSE BURKHARD ,  WALTERSDORFER ANNA ,  KERN MANFRED ,  LUMMEN PETER ,  BONIN WERNER

IPC: A01N43/54 ,  A01N43/90 ,  A01P3/00 ,  A01P7/02 ,  A01P7/04 ,  C07D239/34 ,  C07D239/42 ,  C07D239/46 ,  C07D239/52 ,  C07D239/60 ,  C07D239/88 ,  C07D239/94 ,  C07D401/12 ,  C07D405/12 ,  C07D491/048 ,  C07D495/04 ,  C07D239/28 ,  C07D239/72 ,  C07D401/00 ,  C07D409/12 ,  C07F7/10 ,  A01N55/00 ,  A61K31/505 ,  A61K31/695

Abstract: The invention relates to compounds of the formula defined in the description, X is NH or oxygen and E is a bond or a 1- to 4-membered carbon chain, to a process for their preparation, to agents containing them, and to their use in the control of pests and as fungicides.

公开(公告)号：ZA9207305B

公开(公告)日：1993-03-29

申请号：ZA9207305

申请日：1992-09-24

Applicant: HOECHST AG

Inventor： PREUSS REINER ,  SALBECK GERHARD ,  SCHAPER WOLFGANG ,  BRAUN PETER ,  KNAUF WERNER ,  SACHSE BURKHARD ,  WALTERSDORFER ANNA ,  KERN MANFRED ,  LUEMMEN PETER

IPC: A01N43/54 ,  A01N43/90 ,  C07D239/34 ,  C07D239/47 ,  C07D239/52 ,  C07D239/60 ,  C07D239/70 ,  C07D239/88 ,  C07D409/12 ,  C07D495/04 ,  C07F7/18 ,  C07D ,  A01N

CPC classification number: C07F7/1856 ,  A01N43/54 ,  A01N43/90 ,  C07D239/34 ,  C07D239/52 ,  C07D239/60 ,  C07D239/70 ,  C07D239/88 ,  C07D409/12 ,  C07D495/04