Abstract:
The present invention provides a microfluidic device comprising a body structure which comprises a fusible material. Selective application of energy (e.g. scanning radiation) produces and maintains a network of microchannels by fusing the material. There may be ports in fluid communication with one or more channels. The subject devices find use in a variety of electrophoretic applications, including clinical assays, high throughput screening for genomics, proteomics and pharmaceutical applications, point-of-care in vitro diagnostics, molecular genetic analysis and nucleic acid diagnostics, cell separations, and bioresearch generally.
Abstract:
The present disclosure relates to a method for generating a three-dimensional microstructure in an object. In one embodiment, a method for fabricating a microscopic three-dimensional structure is provided. A work piece is provided that includes a target area at which the three-dimensional structure is to be fabricated. The target area has a plurality of virtual dwell points. A shaped beam is provided to project onto the work piece. The intersection of the shaped beam with the work piece defines a beam incidence region that has a desired shape. The beam incidence region is sufficiently large to encompass multiple ones of the virtual dwell points. The shaped beam is moved across the work piece such that different ones of the virtual dwell points come into it and leave it as the beam moves across the work piece thereby providing different doses to different ones of the virtual dwell points as the different dwell points remain in the beam incidence region for different lengths of time during the beam scan. In this way, a desired dose array of beam particles is applied onto the target area to form the three dimensional microstructure.
Abstract:
A method of manufacturing a plurality of through-holes (132) in a layer of first material, for example for the manufacturing of a probe (100) comprising a tip containing a channel. To manufacture the through-holes (132) in a batch process, - a layer of first material is deposited on a wafer (200) comprising a plurality of pits (210) - a second layer is provided on the layer of first material, and the second layer is provided with a plurality of holes at central locations of the pits (210); - using the second layer as a shadow mask when depositing a third layer (240) at an angle, covering a part of the first material with said third material (240) at the central locations, and - etching the exposed parts of the first layer using the third layer (240) as a protective layer.
Abstract:
A laser processing method for forming a hole in a sheet-like object to be processed made of silicon comprises a depression forming step of forming a depression in a part corresponding to the hole on a laser light entrance surface side of the object, the depression opening to the laser light entrance surface; a modified region forming step of forming a modified region along a part corresponding to the hole in the object by converging a laser light at the object after the depression forming step; and an etching step of anisotropically etching the object after the modified region forming step so as to advance the etching selectively along the modified region and form the hole in the object; wherein the modified region forming step exposes the modified region or a fracture extending from the modified region to an inner face of the depression.
Abstract:
A MEMS chip having at least two chip components bonded together by means of an adhesive layer that is applied to at least one of two mating bonding surfaces of the two components, wherein a pattern of finely distributed micro-cavities is formed in at least one of the two mating bonding surfaces, said micro-cavities being arranged to accommodate a major part of the adhesive.
Abstract:
The present invention is in the field of a method for removing a high definition nanostructure in a partly free-standing layer, the layer, a sensor comprising said layer, a use of said sensor, and a method of detecting a species, and optional further characteristics thereof, using said sensor. The sensor and method are suited for detecting single ions, molecules, low concentrations thereof, and identifying sequences of base pairs, e.g. in a DNA-strand.
Abstract:
Die Erfindung betrifft ein dreidimensionales, mikromechanisches Bauteil aus einem C- oder Si-enthaltenden Basismaterial oder aus Glaskeramiken oder aus Al-haltigen Glaskeramiken, das sich dadurch auszeichnet, dass in den Flanken eines derartigen Bauteils, ausgehend von mindestens einer Oberflächenkante mindestens einer Oberfläche, in der/den Seitenkante/n eine Fase angeordnet ist, die einen Winkel α 1 von 40° bis 65° aufweist. Die Erfindung betrifft weiterhin ein Verfahren zur Herstellung eines derartigen Bauteils, wobei das vorstrukturierte Bauteil auf einem Wafer bzw. über Haltestege in einem Wafer befestigt ist und die Fase durch Sputtern und/oder durch lonen- bzw. Plasmaätzen eingebracht wird.