Abstract:
본 발명은 상관 간섭 분광 장치가 샘플의 스펙트럼 특성을 검출하는 것을 기재하였으며, 장치는 광자로 샘플을 여기시키는 전자기 방사원과, 검출기에 광자의 도달 시간을 검출하도록 구성되고, 또한 다른 광자들의 도달 시간들 사이의 지연을 검출하도록 구성된 검출기로 구성된다. 상기 장치는 또한, 검출기에의 광자들의 도달 사이를 분석하도록 구성된 자기 상관기로 구성될 수 있다. 장치는 또한 다른 스펙트럼 검출 및 예를 들어 라만 분광 및 감쇠 전반사 분광과 같은 특성 시스템과 함께 사용될 수 있다. 본원에는 또한 상관 간섭 분광 장치를 통합한 방법, 시스템 및 키트가 제공된다.
Abstract:
A radiation measuring device for measuring electromagnetic radiation originating from an external source. The radiation measuring device includes, a spectrometer, a pyranometer, a pyrgeometer, a diffuser, and a control unit. The spectrometer and a pyranometer are positioned in a sensor zone of a housing of the radiation measuring device. The spectrometer measures visible shortwave radiation and near-infrared shortwave radiation received at the sensor zone. The pyranometer measures shortwave radiation received at the sensor zone. The pyrgeometer is positioned in another sensor zone of the housing and measures longwave radiation received at the other sensor zone. The control unit receives radiation measurements from the spectrometer, pyranometer, and pyrgeometer. A corrected amount of radiation received at the sensor zones of the radiation measuring device is determined from the received radiation measurements. Other embodiments are described and claimed.
Abstract:
A multidimensional spectrometer encodes frequency information into laser pulses so that a frequency insensitive detector may be used to collect data for a multi- dimensional spectrograph only from intensity information and knowledge of a modulation providing the encoding. In one embodiment the frequency encoding may be done by a conventional interferometer greatly simplifying construction of the spectrometer.
Abstract:
A multidimensional spectrometer encodes frequency information into laser pulses so that a frequency insensitive detector may be used to collect data for a multi- dimensional spectrograph only from intensity information and knowledge of a modulation providing the encoding. In one embodiment the frequency encoding may be done by a conventional interferometer greatly simplifying construction of the spectrometer.
Abstract:
Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM).
Abstract:
An apparatus and method for measuring Raman-type spectra using optical dispersion to convert an optical spectrum into a waveform which can be detected directly in the time domain without the use of a conventional spectrometer. In the example of stimulated Raman spectroscopy, the apparatus and method exposes a sample to a chirped, pulsed probe beam and a Raman pump beam and the resulting Raman spectra is detected by an optical detector in the time domain, and analyzed. Alternatively, the Raman spectra from the probe and pump beams is chirped with a dispersive element prior to detection and analysis. Each probe pulse provides a snapshot of the Raman spectrum that is sampled in time so that neither repetitive waveforms nor static samples are required. Therefore, high speed acquisitions and high throughput assays can be conducted. To facilitate detection, these spectral signals can also be amplified using distributed Raman amplification directly in the dispersive element.
Abstract:
Application of digital light processor (DLP) systems in monochromotor, spectrophotometer or the like systems to mediate selection of individual wavelengths, and/or to image elected regions of a sample in an imaging ellipsometer, imaging polar imeter, imaging ref lectometer, imaging spectrophotometer r and/or to provide chopped beams.
Abstract:
The invention relates to a method of determining the autocorrelation function g(t) of an optical signal. The inventive method comprises the following steps consisting in: determining the instants (t
Abstract:
Encoded spatio-spectral information processing is performed using a system having a radiation source (12), wavelength dispersion device (16) and two-dimensional switching array (18), such as digital micro-mirror array (DMA). In one aspect, spectral components from a sample (24) are dispersed in space and modulated separately by the switching array, each element of which may operate according to a predetermined encoding pattern. The encoded spectral components can then be detected and analyzed. In a different aspect, the switching array (18) can be used to provide a controllable radiation source for illuminating a sample (24) with radiation patterns that have predetermined characteristics and separately encoded components. Various applications are disclosed.
Abstract:
A method for characterizing samples having fluorescent particles, by monitoring fluctuating intensities of radiation emitted by said particles in at least one measurement volume, the monitoring being performed by at least one detection means, said method comprising the steps of: a) measuring in a repetitive mode a length of time intervals between photon counts, b) determining a function or a series of functions of the length of said time intervals, c) determining a function of at least one specific physical property of said particles on basis of said function or said series of functions of the length of time intervals, by finding a close fit between the experimentally determined and a theoretical function or series of functions of the length of said time intervals, the latter of which takes into account parameters of the spatial brightness function characteristic for the optical set-up.