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公开(公告)号：KR1020130104240A
公开(公告)日：2013-09-25
申请号：KR1020120025594
申请日：2012-03-13
Applicant: 대구가톨릭대학교산학협력단 , (주)에스.앤.디
IPC: A61K31/404 , A61K36/815 , A61P3/00
CPC classification number: A61K36/815 , A23V2200/326 , A61K2236/333
Abstract: PURPOSE: An anticholesterol composition is provided to suppress the activities of HMG-CoA reductase and acyl-CoA:cholesterol acyltransferase (ACAT) and to lower cholesterol in serum using a Lycii radicis cortex-derived tyramine derivative, thereby preventing hyperlipidemia. CONSTITUTION: A method for preparing an anticholesterol tyramine derivative comprises the steps of: extracting Lycii radicis cortex powder with an ethanol solution and filtering the extract; concentrating the extract by compression; and performing Sep-Pak C18 cartridges column chromatography. The derivative is trans-N-p-coumaroyltyramine (CT) or trans-N-feruloyltyramine (FT). A functional food composition for anticholesterol and antioxidative effects contains the tyramine derivative as an active ingredient.
Abstract translation: 目的：提供一种抗胆固醇组合物，以抑制HMG-CoA还原酶和酰基辅酶A：胆固醇酰基转移酶（ACAT）的活性，并使用雷公藤皮质衍生的酪胺衍生物降低血清中的胆固醇，从而预防高脂血症。 构成：制备抗胆固醇酪胺衍生物的方法，包括以下步骤：用乙醇溶液提取李子皮质粉末并过滤提取物; 通过压缩浓缩提取物; 并进行Sep-Pak C18柱色谱。 衍生物是反式-N-对 - 芳香酰酪氨酸（CT）或反式N-阿魏酰酪胺（FT）。 用于抗胆固醇和抗氧化作用的功能性食品组合物含有酪胺衍生物作为活性成分。
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公开(公告)号：KR101301695B1
公开(公告)日：2013-08-30
申请号：KR1020120082792
申请日：2012-07-27
Applicant: 대구가톨릭대학교산학협력단
Inventor： 김재은
IPC: H02N2/18
CPC classification number: H02N2/183 , H01L41/0536 , H01L41/1136
Abstract: PURPOSE: An energy harvesting apparatus is provided to widen the frequency band of an electric output by changing vibrating energy into electric energy. CONSTITUTION: An energy harvesting apparatus includes a cantilever (110), a movable mass (140), an elastic member (130), and an electric energy generator (150). One end of the cantilever is fixed to a structure (1). The cantilever generates a vibration dislocation by receiving a vibration from the structure. The movable mass is arranged on the other end of the cantilever and moves in the length direction of the cantilever. The elastic member fixes the movable mass to move on the cantilever. The electric energy generator is arranged on the cantilever and changes the vibrating energy of the cantilever to electric energy by being deformed when the cantilever generates the vibration dislocation. [Reference numerals] (AA) Vibration
Abstract translation: 目的：提供能量收集装置，通过将振动能变为电能来扩大电力输出的频带。 构成：能量收集装置包括悬臂（110），可移动块（140），弹性构件（130）和电能发生器（150）。 悬臂的一端固定在结构（1）上。 悬臂通过接收来自结构的振动而产生振动位错。 可移动质量块布置在悬臂的另一端，并在悬臂的长度方向上移动。 弹性构件固定可移动物体在悬臂上移动。 电力发生器布置在悬臂上，当悬臂产生振动位错时，通过变形将悬臂的振动能量改变为电能。 （附图标记）（AA）振动
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公开(公告)号：KR101301372B1
公开(公告)日：2013-08-29
申请号：KR1020110120681
申请日：2011-11-18
Applicant: 대구가톨릭대학교산학협력단
Abstract: 본 발명에 따른 뇌파신호를 이용한 사용자 맞춤형 경혈 자극방법은 감정제어모드, 집중력향상모드 또는 건강관리모드 중 어느 하나의 운전모드를 사용자로부터 입력받는 제1단계, 사용자의 손에 대해 미리 정해진 복수의 경혈점 중 상기 입력된 운전모드에서 자극할 경혈점인 제어경혈점을 설정하는 제2단계, 및 상기 입력된 운전모드에 대해 미리 저장된 방식으로 사용자의 뇌파를 측정하여 현재 사용자의 뇌파상태를 판단하고, 판단결과에 따라 상기 제어경혈점을 자극하는 제3단계를 포함하는 것을 특징으로 한다.
본 발명에 따른 뇌파신호를 이용한 사용자 맞춤형 경혈 자극방법은 상기 측정한 사용자 뇌파의 분석결과 건강상태에 이상이 있다고 판단되는 경우에는 장갑형태로 구성된 경혈 자극부에 의해 사용자의 현재 뇌파상태와 자극에 대한 사용자 고유의 뇌파 반응특성을 고려하여 설정된 제어경혈점을 자극하여 사용자의 뇌파상태를 정상상태로 유도하는 방식이기 때문에, 다수인에 대해 통계적으로 정해진 자극점을 자극하는 종래 기술과 대비할 때 사용자의 뇌파상태를 현저히 효과적으로 정상상태로 유도할 수 있다는 장점이 있다.-
公开(公告)号：KR1020130093371A
公开(公告)日：2013-08-22
申请号：KR1020120014927
申请日：2012-02-14
Applicant: 대구가톨릭대학교산학협력단 , 최상원
Abstract: PURPOSE: A production method of a mulberry leaf extract is provided to mass-produce refined powder containing flavonoid with the high value from mulberry leaves. CONSTITUTION: Mulberry leaves harvested in June are pre-dried in the shade for a week, and dried in a 45-55°C hot air drier for two days until the water content is 10 ± 3%. 100 kg of dried mulberry leaves is mixed with 650 kg of 30% ethanol solution for ultrasound extracting for 12 hours at 40-50°C, and the mixture is filtered and decompress-concentrated. The concentrate is dissolved in a 30% ethanol solution before settling for one night at room temperature, and centrifugal-separating precipitates. Supernatant is decompress-concentrated, and dissolved in a 20% ethanol solution. The concentrate passes through a Diaion HP-20 adsorption ion resin for absorbing flavonoid, and is eluted by 30% and 50% ethanol solutions. The silica gel and Sephadex column chromatography is conducted on each fraction successively. [Reference numerals] (AA) Mulberry leaves; (BB) Extraction (650 kg, 20% ethanol solution, ultrasound extractor, 50°C, 12 hours, 2 times); (CC) Filtration; (DD) Filtrate; (EE,JJ) Decompress-concentration; (FF) Mulberry leaf ethanol extract (23 kg); (GG) Re-dissolving (100 kg, 30% ethanol solution); (HH) Settling for one night; (II) Supernatant; (KK) Mulberry leaf ethanol extract (21.2 kg); (LL) Suspension (50 kg, 20% ethanol solution); (MM) Diaion HP-20 column chromatography; (NN) 30% ethanol solution fraction; (OO) 50% ethanol solution fraction; (PP) Mulberry extract I (1.1 kg); (QQ) Mulberry extract II (0.73 kg)
Abstract translation: 目的：提供桑叶提取物的生产方法，从桑叶中大量生产含有黄酮类化合物的精制粉末。 构成：6月份收获的桑叶在阴凉处预干燥一周，然后在45-55°C热空气干燥器中干燥两天，直到含水量为10±3％。 将100kg干桑叶与650kg 30％乙醇溶液混合，在40-50℃下超声提取12小时，将混合物过滤并减压浓缩。 将浓缩物溶解在30％乙醇溶液中，然后在室温下沉降一夜，然后离心分离沉淀。 上清液减压浓缩，溶于20％乙醇溶液。 浓缩物通过Diaion HP-20吸附离子树脂吸收黄酮，并被30％和50％乙醇溶液洗脱。 依次对各部分进行硅胶和Sephadex柱层析。 （附图标记）（AA）桑叶; （BB）提取（650kg，20％乙醇溶液，超声提取器，50℃，12小时，2次）; （CC）过滤; （DD）滤液; （EE，JJ）减压浓缩; （FF）桑叶乙醇提取物（23kg）; （GG）再溶解（100kg，30％乙醇溶液）; （HH）结算一晚; （二）上清液; （KK）桑叶乙醇提取物（21.2公斤）; （LL）悬浮液（50kg，20％乙醇溶液）; （MM）Diaion HP-20柱色谱; （NN）30％乙醇溶液级分; （OO）50％乙醇溶液级分; （PP）桑树提取物I（1.1kg）; （QQ）桑树提取物II（0.73公斤）
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105.发明公开
公开(公告)号：KR1020130093370A
公开(公告)日：2013-08-22
申请号：KR1020120014926
申请日：2012-02-14
Applicant: 대구가톨릭대학교산학협력단 , 최상원
CPC classification number: A23L19/03 , A23L33/105 , A23V2002/00 , A23V2200/302 , A23V2200/3262 , A23V2200/328 , A61K8/97 , A61K2800/85 , C12G3/02
Abstract: PURPOSE: A production method of anti-liver toxicity, ant-diabetic, anti-aging, and anti-oxidative dihydroflavonol is provided to mass produce the dihydroflavonol by fermenting mulberry wine. CONSTITUTION: Mulberries are fermented and aged to obtain mulberry wine. The mulberry wine is mixed with ionized water with the same amount. The mixed solution is mixed with ethyl acetate for fractioning and separating supernatant. The ethyl acetate fraction is dissolved in a 20% ethane solution, and settled for one day to obtain supernatant. The supernatant is passed through a Diaion HP-20 ion resin for absorbing a flavonol compound, eluted by using a 50% ethanol solution, and concentrated to obtain a mulberry wine extract. ODS-A and Sephadex LH-20 column chromatography are successively performed to the mulberry wine extract.
Abstract translation: 目的：提供抗肝毒性，抗糖尿病，抗衰老和抗氧化二氢黄酮醇的生产方法，通过发酵桑树酒大量生产二氢黄酮醇。 构成：桑树发酵和老化以获得桑berry酒。 桑叶酒与相同量的电离水混合。 将混合溶液与乙酸乙酯混合以分级和分离上清液。 将乙酸乙酯级分溶于20％乙烷溶液中，沉降1天，得到上清液。 将上清液通过Diaion HP-20离子树脂吸收黄酮醇化合物，使用50％乙醇溶液洗脱，浓缩得到桑树提取物。 依次对桑树提取物进行ODS-A和Sephadex LH-20柱层析。
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Patent Agency Ranking
公开(公告)号：KR101291343B1
公开(公告)日：2013-07-30
申请号：KR1020110022097
申请日：2011-03-11
Applicant: 대구가톨릭대학교산학협력단
IPC: A61K31/737 , A61K36/28 , A61K36/484 , A61P17/00
Abstract: 본 발명은 후코이단 및 생약성분 추출물을 함께 유효성분으로 포함하는 아토피피부염 증상 개선용 크림에 관한 것으로, 상기 크림은 아토피피부염 증상을 현저히 완화시키는 효과를 나타내어, 가려움증으로 인한 긁기 횟수를 감소시키고, 혈청 IgE 농도를 감소시키며, 히스타민 농도를 감소시키고, 전체 피부층이 안정되며 세포 침윤 현상이 적으며, 비만 세포수가 감소하는 효과가 있었다.
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公开(公告)号：KR1020130077009A
公开(公告)日：2013-07-09
申请号：KR1020110145486
申请日：2011-12-29
Applicant: 대구가톨릭대학교산학협력단
Abstract: PURPOSE: An ankle flexibility measuring instrument is provided to objectively measure the rotation range of an ankle for an objective and accurate diagnosis on an ankle ligament injury. CONSTITUTION: An ankle flexibility measuring instrument (100) comprises a base unit (10) which occupies the lower part of the instrument; a leg fixing unit (20) which is installed at an angle on the top of the base unit to form a space for accommodating a leg; an angle display unit (40) which includes a hollow inside and angle gradations on the surface and is attached to one side of the leg fixing unit; and an ankle rotating unit (50) which is rotatably attached to the angle display unit, displays on the surface an indicator that shows the rotation angle from a reference point, and includes a space for accommodating a foot.
Abstract translation: 目的：提供踝关节柔韧性测量仪器，客观地测量踝关节的旋转范围，以进行目标和踝韧带损伤的准确诊断。 构成：脚踝柔性测量仪器（100）包括占据仪器下部的基座单元（10）; 腿部固定单元（20），其以一定角度安装在基座单元的顶部上以形成用于容纳腿部的空间; 角度显示单元（40），其在所述表面上包括中空的内角和斜度，并且附接到所述腿固定单元的一侧; 以及可旋转地安装在角度显示单元上的脚踝旋转单元（50），在表面上显示出从参考点显示旋转角度的指示器，并且包括用于容纳脚的空间。
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公开(公告)号：KR101259150B1
公开(公告)日：2013-05-08
申请号：KR1020090136174
申请日：2009-12-31
Applicant: 대구가톨릭대학교산학협력단 , 주식회사 에이징
Abstract: 본발명은알긴산과화산석을유효성분으로함유하는필오프타입의분말형미용팩용화장료조성물에관한것으로, 필수구성성분으로사용하는알긴산에존재하는 Gluronic acid 단량체가 Ca 이온을만나면너무나빨리 gell 화하여필름을형성하는현상을억제하기위하여겔링지연제와알긴산의분산과균일한필름형성을돕는중성내지약알칼리성의분산기제를첨가하여서됨을특징으로하는것이다.
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公开(公告)号：KR1020130034276A
公开(公告)日：2013-04-05
申请号：KR1020110098194
申请日：2011-09-28
Applicant: 대구가톨릭대학교산학협력단
IPC: C07D307/58 , C07D309/32 , A61K31/34 , A61K36/73
Abstract: PURPOSE: An aerial part extract of Aruncus dioicus and a novel compound isolated from the same are provided to treat leukemia or acute lymphatic leukemia including Jurkat T leukemia cells. CONSTITUTION: A pharmaceutical composition for treating leukemia contains a compound of structural formula I, II, III, IV, or V or a pharmaceutically acceptable salt thereof. The compound is isolated from an aerial part extract of Aruncus dioicus. The compound or the salt has antioxidation activity and/or cytotoxicity to Jurkat T cells.
Abstract translation: 目的：提供云杉的地上部分提取物和从其分离的新型化合物，用于治疗白血病或急性淋巴细胞白血病，包括Jurkat T白血病细胞。 构成：用于治疗白血病的药物组合物含有结构式I，II，III，IV或V的化合物或其药学上可接受的盐。 该化合物与云杉的地上部分提取物分离。 化合物或盐对Jurkat T细胞具有抗氧化活性和/或细胞毒性。
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公开(公告)号：KR1020130032219A
公开(公告)日：2013-04-01
申请号：KR1020110120681
申请日：2011-11-18
Applicant: 대구가톨릭대학교산학협력단
CPC classification number: A61H39/04 , A61B5/0476 , A61H23/006 , A61H23/0254 , A61H39/02 , A61H2201/1635 , A61H2201/5035 , A61H2205/065 , A61H2230/105 , A61N1/18
Abstract: PURPOSE: A user personalized meridian point stimulating method using an electroencephalogram is provided to guide brain wave of user to a normal state by stimulating the set meridian point considering the brain wave reaction characteristic of distinct user according to the current brain wave state and stimulus of user. CONSTITUTION: A user personalized meridian point stimulating apparatus using an electroencephalogram comprises the following steps. Any one operational mode of an emotion control mode, a concentration improving mode, or a health maintaining mode is entered by a user(S10). Among the preset multiple meridian points of the user's hand, a control meridian point is set to stimulate on the entered operational mode(S50). By the pre-saved method of the entered operational mode, the brain wave of user is calculated and determined on current brain wave state of user, and the control meridian point is stimulated based on the determinant(S120). [Reference numerals] (AA) Start; (BB) End; (S10) Receiving a user information input signal; (S100) Is there a channel(i) requiring emotion control?; (S110) Determining a brain wave band(j) requiring emotion control in each channel(i); (S120) Successively stimulating control meridian points corresponding to the brain wave band(j) in each channel(i); (S20) Receiving a driving mode selection signal; (S30) Driving mode is an emotion control mode?; (S40) Receiving a stimulating time setting signal; (S50) Receiving a control meridian point setting algorithm selection signal; (S60) Customized algorithm for a user?; (S70) Measuring brain waves in a stabilizing period, an acupuncture applying period, and an acupuncture removing period on each meridian point; (S80) Setting control meridian points according to brain wave bands in each channel by using the brain wave measurement values; (S85) Setting control meridian points according to brain wave bands in each channel by using prestored data; (S90) Measuring the brain wave of a user and calculating an SASI value of each channel;
Abstract translation: 目的：提供一种使用脑电图的用户个性化子午线点刺激方法，通过根据当前脑波状态和用户的刺激考虑不同用户的脑波反应特性，通过刺激设定子午线点将用户脑波引导到正常状态 。 构成：使用脑电图的用户个性化经络点刺激装置包括以下步骤。 由用户输入情绪控制模式，浓度改善模式或健康维持模式的任何一种操作模式（S10）。 在用户手的预设多个子午点中，设置控制子午线点以在输入的操作模式下进行刺激（S50）。 通过输入操作模式的预先保存的方法，根据用户的当前脑波状态计算并确定用户的脑波，并根据行列式刺激控制子午点（S120）。 （附图标记）（AA）开始; （BB）结束; （S10）接收用户信息输入信号; （S100）是否有通道（i）需要情感控制？ （S110）确定在每个信道（i）中需要情绪控制的脑波段（j）; （S120）连续地刺激对应于每个通道（i）中的脑波带（j）的控制子午线点; （S20）接收驱动模式选择信号; （S30）驾驶模式是情绪控制模式 （S40）接收刺激时间设定信号; （S50）接收控制子午点设定算法选择信号; （S60）用户的定制算法？ （S70）在稳定期测量脑电波，针灸施药期和每个经络点的针灸去除期; （S80）通过使用脑波测量值，根据每个通道中的脑波带设置控制子午线点; （S85）通过使用预存数据，根据每个通道中的脑波段设置控制子午线点; （S90）测量用户的脑波并计算每个通道的SASI值;
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