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公开(公告)号:KR1020120100859A
公开(公告)日:2012-09-12
申请号:KR1020120082039
申请日:2012-07-26
Applicant: 재단법인 제주테크노파크
CPC classification number: A61K36/60 , A23L33/105 , A23V2002/00 , A23V2200/324
Abstract: PURPOSE: An anti-inflammatory composition using Ficus erecta leaf extract is provided to suppress IL-1beta generation and iNOS and COX-2 expression. CONSTITUTION: An anti-inflammatory composition contains Ficus erecta leaf extract as an active ingredient. The extract is selected from: extract prepared with alcohol of 1-5 carbon atoms, acetone, hexane, ethyl acetate, dichloromethane, water or a mixture thereof; extract of a fraction solvent layer prepared by fractioning solid extract with water and hexane, water and dichloromethane, or water and ethyl acetate; and extract prepared by suspending the solid extract in the water and fractioning with hexane, dichloromethane, and ethyl acetate in order. The composition is a pharmaceutical composition and food composition.
Abstract translation: 目的:提供使用Ficus erecta叶提取物的抗炎组合物,以抑制IL-1beta的产生和iNOS和COX-2的表达。 构成:抗炎组合物含有榕叶提取物作为活性成分。 提取物选自:用1-5个碳原子的醇制备的提取物,丙酮,己烷,乙酸乙酯,二氯甲烷,水或其混合物; 通过用水和己烷,水和二氯甲烷或水和乙酸乙酯分离固体提取物制备的级分溶剂层的提取物; 和通过将固体提取物悬浮在水中制备的提取物,并依次用己烷,二氯甲烷和乙酸乙酯分馏。 组合物是药物组合物和食物组合物。
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公开(公告)号:KR1020120062615A
公开(公告)日:2012-06-14
申请号:KR1020110109289
申请日:2011-10-25
Applicant: 재단법인 제주테크노파크
CPC classification number: A61K36/03 , A61K8/9706 , A61K9/0014 , A61K9/06 , A61K2236/333 , Y10S514/859
Abstract: PURPOSE: An external use skin composition containing Padina arborescens extract and/or fraction thereof is provided to ensure antibacterial function and to treat acne. CONSTITUTION: An antibacterial external use skin composition contains ethanol solution extract of Padina arborescens or hexane fraction, dichloromethane fraction thereof, or ethyl acetate fraction thereof as an active ingredient. The external use skin composition has antibacterial function against Staphylococcus aureus, Staphylococcus epidermidis, or Propionibacterium acne. The external use skin composition is a cosmetic, cleansing, or pharmaceutical composition.
Abstract translation: 目的:提供含有Padina arborescens提取物和/或其部分的外用皮肤组合物,以确保抗菌功能并治疗痤疮。 构成:抗菌外用皮肤组合物含有Padina arborescens或己烷级分的乙醇溶液提取物,其二氯甲烷级分或其乙酸乙酯级分作为活性成分。 外用皮肤组合物对金黄色葡萄球菌,表皮葡萄球菌或痤疮丙酸杆菌具有抗菌作用。 外用皮肤组合物是化妆品,清洁剂或药物组合物。
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公开(公告)号:KR1020110084132A
公开(公告)日:2011-07-21
申请号:KR1020110012510
申请日:2011-02-11
Applicant: 재단법인 제주테크노파크 , 제주특별자치도
CPC classification number: A61K8/987 , A23L33/10 , A61K35/616 , A61Q19/005 , A61Q19/007 , A61Q19/08 , A61Q19/10
Abstract: PURPOSE: A composition containing Stichopus japonicus extract is provided to improve skin condition and to manufacture a cosmetic products, soap, drugs, and foods. CONSTITUTION: A composition for improving skin condition contains Stichopus japonicus extract as an active ingredient. The skin condition includes enhancement of skin elasticity, anti-aging, and skin moisturizing and skin irritation relief. The composition is a cosmetic, pharmaceutical, or food composition. The cosmetic composition is soap.
Abstract translation: 目的:提供含有日本St us提取物的组合物,以改善皮肤状况并制造化妆品,肥皂,药物和食品。 构成:用于改善皮肤状况的组合物含有日本St us提取物作为活性成分。 皮肤状况包括增强皮肤弹性,抗衰老,皮肤保湿和皮肤刺激缓解。 组合物是化妆品,药物或食品组合物。 化妆品组合物是肥皂。
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114.
公开(公告)号:KR1020090118154A
公开(公告)日:2009-11-18
申请号:KR1020080043774
申请日:2008-05-13
Applicant: 재단법인 제주테크노파크
IPC: A61K36/185 , A61P17/18 , A61P35/00
Abstract: PURPOSE: A composition containing Quercus acuta Thunb extract is provided to ensure the effect of DNA damage suppression and cancer cell proliferation suppression. CONSTITUTION: A method for producing fraction of Quercus acuta Thunb extract comprises: a step of preparing stems with leaves of Quercus acuta Thunb then pulverizing; a step of extracting the pulverized Quercus acuta Thunb powder with ethanol; a step of decompress-concentrating then suspending with distilled water; and a step of extracting with hexane, dichloromethane, ethylacetate, butanol, and water. A composition for antioxidation contains fraction of Quercus acuta Thunb extract.
Abstract translation: 目的:提供含有栎属藜提取物的组合物,以确保DNA损伤抑制和癌细胞增殖抑制的作用。 构成:生产栎属栎提取物的方法,包括:用槲皮栎树叶制备茎的步骤,然后粉碎; 用乙醇提取粉碎的栎树栎粉末的步骤; 减压浓缩步骤,然后用蒸馏水悬浮; 和用己烷,二氯甲烷,乙酸乙酯,丁醇和水萃取的步骤。 用于抗氧化的组合物含有栎属栎提取物的分数。
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115.
公开(公告)号:KR1020080020738A
公开(公告)日:2008-03-06
申请号:KR1020060083944
申请日:2006-09-01
Applicant: 재단법인 제주테크노파크
CPC classification number: A61K36/54 , A23V2200/304 , A61K2236/33 , Y10S514/825
Abstract: A composition comprising the extract of Litsea japonica is provided to prevent and treat inflammatory disease and metabolic bone disease including osteoporosis and osteopetrosis by inhibiting inflammation and bone metabolic factors including IL-6(interleukin-6), COX-2(cyclooxygenase-2) and PGE2(prostaglandin E2) without side effects. A composition for preventing and treating inflammatory disease and metabolic bone disease comprises the extract of Litsea japonica which is prepared by drying leaf, stem or fruit of Litsea japonica juss in the shade, pulverizing the dried Litsea japonica juss, dipping the pulverized Litsea japonica juss in 80% ethanol, sonicating the Litsea japonica juss solution for 1 hour, repeating the sonication in three times to prepare the ethanol extract of Litsea japonica juss, collecting the supernatant and concentrating the supernatant under reduced pressure, suspending the concentrate in distilled water, and extracting the suspension with hexane, dichloromethane, ethyl acetate and butanol sequentially, and is formulated as food additives or drink.
Abstract translation: 提供包含日本蓟马提取物的组合物,通过抑制炎症和包括IL-6(白细胞介素-6),COX-2(环氧合酶-2)和骨质疏松素-2)在内的骨代谢因子来预防和治疗包括骨质疏松和骨质疏松的炎性疾病和代谢性骨病, PGE2(前列腺素E2)无副作用。 用于预防和治疗炎性疾病和代谢性骨疾病的组合物包括通过在树荫下干燥荔枝枣的叶,茎或果实制备的荔枝提取物,粉碎干燥的枸杞,将粉碎的荔枝粳稻 80%乙醇,将Litsea japonica juss溶液超声处理1小时,三次重复超声处理,制备日本it杷的乙醇提取物,收集上清液,减压浓缩上清液,将浓缩物悬浮于蒸馏水中,萃取 依次用己烷,二氯甲烷,乙酸乙酯和丁醇悬浮,配制成食品添加剂或饮料。
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公开(公告)号:KR1020080020736A
公开(公告)日:2008-03-06
申请号:KR1020060083942
申请日:2006-09-01
Applicant: 재단법인 제주테크노파크
Abstract: A composition comprising the extract of Anomala albopilosa is provided to inhibit oxidation, inflammation and bone metabolism factors, so that the composition is useful for prevention and treatment of diseases caused by oxidation, inflammation and bone metabolism disorders including cancer, inflammation, arteriosclerosis, liver disease, rheumatoid arthritis, osteoporosis and osteopetrosis. A composition for preventing and treating diseases caused by oxidation, inflammation and bone metabolism factors comprises the extract of Anomala albopilosa which is prepared by drying imago or larva of Anomala albopilosa in the shade, pulverizing the dried Anomala albopilosa, dipping the dried Anomala albopilosa in 80% ethanol, and extracting the solution with ultrasonic wave in three times for 1 hour in each time, and has at least one effect selected from DPPH(diphenylpicrylhydrazyl) radical removal, xanthine oxidase inhibition, superoxide radical removal and nitric oxide production inhibition.
Abstract translation: 提供了包含Anomala albopilosa的提取物的组合物以抑制氧化,炎症和骨代谢因子,使得该组合物可用于预防和治疗由氧化,炎症和骨代谢障碍引起的疾病,包括癌症,炎症,动脉硬化,肝脏疾病 ,类风湿性关节炎,骨质疏松症和骨硬化症。 用于预防和治疗由氧化,炎症和骨代谢因素引起的疾病的组合物包括通过在阴凉处干燥成虫或黑僵菌的成虫或幼虫制备的黑马的提取物,粉碎干燥的阿诺玛菌(Anomala albopilosa),将干燥的阿诺玛拉(Anomala albopilosa)浸入80 %乙醇,每次用超声波提取溶液3次,每次1小时,并具有至少一种选自DPPH(二苯基丙基酰肼基)自由基去除,黄嘌呤氧化酶抑制,超氧自由基去除和一氧化氮生成抑制作用。
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公开(公告)号:KR1020150131667A
公开(公告)日:2015-11-25
申请号:KR1020140058688
申请日:2014-05-16
Applicant: 재단법인 제주테크노파크 , 제주대학교 산학협력단
CPC classification number: A61K36/04 , A23V2200/318 , A61K8/9706 , A61K2236/333 , Y10S514/857 , Y10S514/886
Abstract: 본발명은꿩꼬리풀추출물을이용한항염증용조성물을개시한다. 구체적으로 LPS(lipopolysaccharide)로자극된대식세포에서 NO 생성억제활성, PGE생성억제활성, 염증성사이토카인(TNF-α, IL-6 및 IL-1β) 생성억제활성그리고 iNOS 및 COX-2 생성억제활성을보이고, LPS로자극된골수유래수지상세포에서염증성사이토카인인 IL-12p40의생성억제활성을보이며, 나아가 IFN-γ로자극된각질형성세포인 HaCaT keratinocytes에서염증성케모카인인 MDC(macrophage-derived chemokine)의생성억제활성을보이는꿩꼬리풀추출물을이용한항염증용조성물을개시한다.
Abstract translation: 公开了使用Ph using提取物的抗炎组合物。 更具体地说,使用枸杞提取物的抗炎组合物对NO的产生,PGE_2的产生,炎性细胞因子(TNF-α,IL-6和IL-1β)的产生以及iNOS和COX的产生表现出抑制活性 -2在脂多糖(LPS)刺激的巨噬细胞中; 对由LPS刺激的骨髓来源的树突状细胞中炎性细胞因子IL-12p40的产生具有抑制活性; 此外; 并且在由IFN-γ刺激的HaCaT角质形成细胞中显示出对作为炎性趋化因子的巨噬细胞来源的趋化因子(MDC)的产生的抑制活性。
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公开(公告)号:KR101562553B1
公开(公告)日:2015-11-04
申请号:KR1020140017478
申请日:2014-02-14
Applicant: 재단법인 경기과학기술진흥원 , 재단법인 제주테크노파크 , 주식회사 테라젠이텍스
Abstract: 본발명은인슐린등에의해분화촉진된지방전구세포의지방세포로의분화를억제하고고지방식이에의한비만유도마우스모델에서체중을감소시키며혈중지질농도를낮추고간의지방축적을억제하는활성을경단구슬모자반추출물을이용한항비만제조성물을개시한다.
Abstract translation: 本发明的分化抑制脂肪细胞的分化在促进前脂肪细胞,并使用这种脂肪饺子抑制降低血脂水平之间脂肪蓄积的活性降低肥胖诱导的小鼠模型重量胰岛素珠马尾藻提取物 Lt。
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