公开(公告)号：CZ21099A3

公开(公告)日：2000-01-12

申请号：CZ21099

申请日：1997-07-14

Applicant: BASF AG

Inventor： MACK HELMUT ,  PFEIFFER THOMAS ,  SEITZ WERNER ,  ZIERKE THOMAS ,  BALKENHOHL FRIEDHELM ,  LANGE UDO

IPC: C07D207/22

公开(公告)号：AU708001B2

公开(公告)日：1999-07-29

申请号：AU4875196

申请日：1996-02-12

Applicant: BASF AG

Inventor： BOHM HANS-JOACHIM ,  HOFFKEN HANS WOLFGANG ,  HORNBERGER WILFRIED ,  KOSER STEFAN ,  MACK HELMUT ,  PFEIFFER THOMAS ,  SEITZ WERNER ,  ZIERKE THOMAS

IPC: A61K31/00 ,  A61K38/55 ,  A61P7/02 ,  C07D205/04 ,  C07D207/16 ,  C07D213/53 ,  C07D213/63 ,  C07D213/72 ,  C07D213/78 ,  C07D213/79 ,  C07D239/28 ,  C07D241/14 ,  C07D241/24 ,  C07D401/12 ,  C07K5/06 ,  C07K5/062 ,  C07K5/078 ,  A61K31/40 ,  A61K31/445 ,  A61K31/495

Abstract: The invention relates to a compound of the formula I: or a salt thereof with a physiologically tolerated acid, or stereoisomers thereof, wherein R 1 , R 2 , A, B, C and D have the meanings described in the specification.

公开(公告)号：HU9800634A2

公开(公告)日：1999-06-28

申请号：HU9800634

申请日：1996-02-06

Applicant: BASF AG

Inventor： BOEHM HANS-JOACHIM ,  HORNBERGER WILFRIED ,  HOEFFKEN HANS WOLFGANG ,  KOSER STEFAN ,  MACK HELMUT ,  PFEIFFER THOMAS ,  SEITZ WERNER ,  ZIERKE THOMAS

IPC: A61K38/55 ,  A61K38/00 ,  A61P7/02 ,  C07K5/06 ,  C07K5/065 ,  C07K5/072 ,  C07K5/087

Abstract: PCT No. PCT/EP96/00472 Sec. 371 Date Jul. 30, 1997 Sec. 102(e) Date Jul. 30, 1997 PCT Filed Feb. 6, 1996 PCT Pub. No. WO96/24609 PCT Pub. Date Aug. 15, 1996Thrombin inhibitors of the formula where R1, A, B and D have the meaning indicated in the description, and intermediates for the preparation thereof are described. The compounds I are suitable for controlling diseases.

公开(公告)号：AU706834B2

公开(公告)日：1999-06-24

申请号：AU4787596

申请日：1996-02-06

Applicant: BASF AG

Inventor： SEITZ WERNER ,  MACK HELMUT ,  ZIERKE THOMAS ,  BOHM HANS-JOACHIM ,  HOFFKEN HANS WOLFGANG ,  KOSER STEFAN ,  PFEIFFER THOMAS ,  HORNBERGER WILFRIED

IPC: A61K38/55 ,  A61K38/00 ,  A61P7/02 ,  C07K5/06 ,  C07K5/065 ,  C07K5/072 ,  C07K5/087

Abstract: PCT No. PCT/EP96/00472 Sec. 371 Date Jul. 30, 1997 Sec. 102(e) Date Jul. 30, 1997 PCT Filed Feb. 6, 1996 PCT Pub. No. WO96/24609 PCT Pub. Date Aug. 15, 1996Thrombin inhibitors of the formula where R1, A, B and D have the meaning indicated in the description, and intermediates for the preparation thereof are described. The compounds I are suitable for controlling diseases.

公开(公告)号：CZ31199A3

公开(公告)日：1999-06-16

申请号：CZ31199

申请日：1997-07-29

Applicant: BASF AG

Inventor： BAUCKE DORIT ,  LANGE UDO ,  MACK HELMUT ,  PFEIFER THOMAS ,  SEITZ WERNER ,  ZIERKE THOMAS ,  HOFFKEN HANS WOLFGANG ,  HORNBERGER WILFRIED GOLDENER

IPC: A61K31/40 ,  A61K31/44 ,  A61K38/00 ,  A61K38/05 ,  A61P1/18 ,  A61P7/02 ,  A61P11/02 ,  A61P11/06 ,  A61P17/00 ,  A61P19/02 ,  A61P29/00 ,  A61P43/00 ,  C07D207/22 ,  C07D211/78 ,  C07K5/00 ,  C07K5/02 ,  C07K5/083 ,  A61K38/02

Abstract: Compounds of the formula Iwhere R, R1, R2, R3, R4, R5 and R6, and l, m and n have the meanings stated in the description, and their preparation are described. The novel compounds are suitable for controlling diseases.

公开(公告)号：CZ48699A3

公开(公告)日：1999-05-12

申请号：CZ48699

申请日：1997-07-29

Applicant: BASF AG

Inventor： BAUCKE DORIT ,  LANGE UDO ,  MACK HELMUT ,  SEITZ WERNER ,  ZIERKE THOMAS ,  HOFFKEN HANS WOLFGANG ,  HORNBERGER WILFRIED

IPC: A61K38/00 ,  A61K38/05 ,  A61P7/02 ,  A61P29/00 ,  A61P35/00 ,  A61P35/04 ,  C07K5/06 ,  C07K5/062 ,  C07K5/065

Abstract: PCT No. PCT/EP97/04104 Sec. 371 Date Feb. 10, 1999 Sec. 102(e) Date Feb. 10, 1999 PCT Filed Jul. 29, 1997 PCT Pub. No. WO98/06741 PCT Pub. Date Feb. 19, 1998Compounds of the formula where A, B, E and D have the meanings indicated in the description, and their preparation are described. The substances are suitable for controlling diseases.

公开(公告)号：TR9900310T2

公开(公告)日：1999-04-21

申请号：TR9900310

申请日：1997-07-29

Applicant: BASF AG

Inventor： BAUCKE DORIT ,  LANGE UDO ,  MACK HELMUT ,  SEITZ WERNER ,  ZIERKE THOMAS ,  HOEFFKEN HANS WOLFGANG ,  HORNBERGER WILFRIED

IPC: A61K38/00 ,  A61K38/05 ,  A61P7/02 ,  A61P29/00 ,  A61P35/00 ,  A61P35/04 ,  C07K5/06 ,  C07K5/062 ,  C07K5/065

CPC classification number: C07K5/06078 ,  A61K38/00

公开(公告)号：NO990662L

公开(公告)日：1999-02-12

申请号：NO990662

申请日：1999-02-12

Applicant: BASF AG

Inventor： BAUCKE DORIT ,  LANGE UDO ,  MACK HELMUT ,  SEITZ WERNER ,  ZIERKE THOMAS ,  HOEFFKEN HANS WOLFGANG ,  HORNBERGER WILFRIED

IPC: A61K38/00 ,  A61K38/05 ,  A61P7/02 ,  A61P29/00 ,  A61P35/00 ,  A61P35/04 ,  C07K5/06 ,  C07K5/062 ,  C07K5/065

Abstract: PCT No. PCT/EP97/04104 Sec. 371 Date Feb. 10, 1999 Sec. 102(e) Date Feb. 10, 1999 PCT Filed Jul. 29, 1997 PCT Pub. No. WO98/06741 PCT Pub. Date Feb. 19, 1998Compounds of the formula where A, B, E and D have the meanings indicated in the description, and their preparation are described. The substances are suitable for controlling diseases.

公开(公告)号：ZA9706637B

公开(公告)日：1999-01-25

申请号：ZA9706637

申请日：1997-07-25

Applicant: BASF AG

Inventor： MACK HELMUT ,  PFEIFFER THOMAS ,  SEITZ WERNER ,  ZIERKE THOMAS ,  BALKENHOHL FRIEDHELM ,  LANGE UDO

IPC: C12P17/04 ,  C07D207/22 ,  C07D401/12 ,  C07D ,  C07B

CPC classification number: C07D207/22

公开(公告)号：AU699501B2

公开(公告)日：1998-12-03

申请号：AU2787595

申请日：1995-06-06

Applicant: BASF AG

Inventor： BOHM HANS-JOACHIM ,  KOSER STEFAN ,  MACK HELMUT ,  PFEIFFER THOMAS ,  SEITZ WERNER ,  HOFFKEN HANS WOLFGANG ,  HORNBERGER WILFRIED

IPC: A61K31/40 ,  A61K38/00 ,  A61K38/05 ,  A61K38/55 ,  A61K47/48 ,  A61P7/02 ,  C07C279/00 ,  C07D205/04 ,  C07D207/06 ,  C07D207/16 ,  C07D207/48 ,  C07D211/60 ,  C07K5/06 ,  C07K5/065 ,  C07K5/072 ,  C07K5/078

Abstract: Compounds of the formula and the salts thereof with physiologically tolerated acids and the stereoisomers thereof, in which the substituents have the meanings stated in the description, are described. Also disclosed are intermediates for their preparation. The compounds are suitable for controlling diseases.