Single-and multi-mode configurations for fiber-optic-coupler biosensors
    111.
    发明申请
    Single-and multi-mode configurations for fiber-optic-coupler biosensors 失效
    光纤耦合器生物传感器的单模和多模配置

    公开(公告)号:US20020127707A1

    公开(公告)日:2002-09-12

    申请号:US10095733

    申请日:2002-03-12

    Abstract: Single-mode and multi-mode fibers to achieve modal splitting and greater sensitivity in an optical fiber coupler for evanescent-wave biosensor applications. A source of light having multiple modes is coupled to the input to one of the multi-mode fibers, with the geometry of necked-down section being such that a limited number of modes may be carried by the multi-mode fiber as the light emerges from the coupler. At least one of the single-mode fibers is supported adjacent the multi-mode fiber to receive and carry one of the limited modes. A biomolecule enveloped by the evanescent field, exhibits a direct or indirect affinity to a binding partner, such that attachment of the binding partner is at least partially responsible for the limited number of modes carried by the multi-mode fiber as the light emerges from the coupler. A system-level implementation of the invention further includes instrumentation for receiving the light from the single-mode fiber carrying one of the limited modes, and determining a characteristic of the binding partner in accordance with the detected mode. The attachment of the binding partner may also causes a change in other detectable optical attributes, such as the magnitude or polarization of the light at one or both of the fiber outputs. The instrumentation may therefore further include a polarization-sensitive optical element supported at one or both of the outputs of the optical fibers, for example, in the form of a polarizing beamsplitter. One or more of the fibers may be pulled substantially without twisting so as to maintain polarization orientation, and the source of light may randomly, circularly, or linearly polarized.

    Abstract translation: 单模和多模光纤实现模式分裂,并且在光纤耦合器中具有更高的灵敏度,用于ev逝波生物传感器应用。 具有多种模式的光源耦合到多模光纤之一的输入端,缩小部分的几何形状使得当光出现时,多模光纤可以承载有限数量的模式 从耦合器。 至少一个单模光纤被支持在多模光纤附近以接收和携带有限模式之一。 由消逝场包围的生物分子对结合配偶体表现出直接或间接的亲和力,使得结合对象的附着至少部分地由多模光纤携带的有限数量的模式负责,因为光从 耦合器 本发明的系统级实现还包括用于从承载有限模式之一的单模光纤接收光的仪器,以及根据检测模式确定绑定伙伴的特性。 绑定伙伴的附着也可能导致其他可检测的光学属性的变化,例如在一个或两个光纤输出端的光的幅度或极化。 因此,仪器可以进一步包括支撑在光纤的一个或两个输出处的偏振敏感光学元件,例如以偏振分束器的形式。 纤维中的一种或多种可以被基本上拉伸而不会扭曲,从而保持偏振取向,并且光源可以随机,圆形或线性偏振。

    Holographic grating spectrum analyzer
    112.
    发明申请
    Holographic grating spectrum analyzer 失效
    全息光栅光谱分析仪

    公开(公告)号:US20020126280A1

    公开(公告)日:2002-09-12

    申请号:US10011236

    申请日:2001-10-19

    Inventor: Thomas L. Mikes

    Abstract: A spectrum analyzer providing an integrated calibration function and for providing that calibration function automatically. The injection of light to be analyzed through a central aperture of a scanning grating onto a focusing reflector provides in combination four traversals of the space therebetween. The spectrometer thus is used to separate wavelength information spacially and receive it back at the same or adjacent aperture(s) to be analyzed by a processing system to establish the spectra for the incident light. The light is typically injected from and received back into optical fibers or other light carrying elements. Calibration light is also applied through the same or adjacent apertures in the grating from a known source and spectra such as Argon to use as a calibration reference by detecting the known spectra peaks and correlating it to grating scan angle. The same structure is also used as a telecommunications channel router by injecting light of multi-channel and thus broadband spectral content into the spectrometer through the central aperture(s) and angling the grating so that a selected channel or channels are reflected back after four passages of the spectral separator to output one or more optical fibers or other guides.

    Abstract translation: 频谱分析仪提供集成校准功能,并自动提供校准功能。 通过扫描光栅的中心孔将待分析的光注入到聚焦反射器上,四者之间的空间组合四次。 因此,光谱仪用于空间分离波长信息并在相同或相邻孔径处接收,以便由处理系统分析以建立入射光的光谱。 光通常从光纤或其他轻载元件注入并接收回。 校准光也通过来自已知源和光谱(例如氩)的光栅中的相同或相邻孔径施加,以通过检测已知光谱峰值并将其与光栅扫描角度相关联来用作校准参考。 同样的结构也被用作通信信道路由器,它通过中心孔和多个通道将光通道注入光谱仪,从而使光纤通过四通道反射回所选择的通道 的光谱分离器以输出一个或多个光纤或其它引导件。

    System and method for self-referencing calibration
    113.
    发明申请
    System and method for self-referencing calibration 有权
    用于自参考校准的系统和方法

    公开(公告)号:US20020109839A1

    公开(公告)日:2002-08-15

    申请号:US10068623

    申请日:2002-02-05

    Abstract: A method of calibrating a spectrographic inspection system, comprises providing a plurality of packages, each of the plurality of packages containing a group of items, wherein each of the groups of items has a known composition, measuring the reflectance value of each of the groups of items and thereby obtaining a reference reflectance value set, normalizing the reference reflectance value set and thereby creating a normalized reference reflectance value set, and storing the normalized reference reflectance value set.

    Abstract translation: 一种校准光谱检查系统的方法,包括提供多个包装,所述多个包装件中的每一个包含一组物品,其中每组物品具有已知组成,测量每组物品的反射率值 从而获得设定的基准反射率值,归一化所设定的基准反射率值,从而生成归一化参考反射率值集合,并存储归一化参考反射率值集合。

    Computed tomography imaging spectrometer (CTIS) with 2D reflective grating for ultraviolet to long-wave infrared detection especially useful for surveying transient events
    114.
    发明申请
    Computed tomography imaging spectrometer (CTIS) with 2D reflective grating for ultraviolet to long-wave infrared detection especially useful for surveying transient events 失效
    具有2D反射光栅的计算机断层成像光谱仪(CTIS),用于紫外至长波红外检测,特别适用于测量瞬态事件

    公开(公告)号:US20020101587A1

    公开(公告)日:2002-08-01

    申请号:US09734242

    申请日:2000-12-04

    CPC classification number: G01J3/02 G01J3/0208 G01J3/18 G01J3/2823 G02B5/1861

    Abstract: The optical system of this invention is an unique type of imaging spectrometer, i.e. an instrument that can determine the spectra of all points in a two-dimensional scene. The general type of imaging spectrometer under which this invention falls has been termed a computed-tomography imaging spectrometer (CTIS). CTIS's have the ability to perform spectral imaging of scenes containing rapidly moving objects or evolving features, hereafter referred to as transient scenes. This invention, a reflective CTIS with an unique two-dimensional reflective grating, can operate in any wavelength band from the ultraviolet through long-wave infrared. Although this spectrometer is especially useful for rapidly occurring events it is also useful for investigation of some slow moving phenomena as in the life sciences.

    Abstract translation: 本发明的光学系统是独特类型的成像光谱仪,即可以确定二维场景中所有点的光谱的仪器。 本发明所属的一般类型的成像光谱仪被称为计算机断层成像光谱仪(CTIS)。 CTIS有能力对包含快速移动物体或演变特征的场景进行光谱成像,以下简称瞬态场景。 本发明具有独特的二维反射光栅的反射CTIS可以在紫外线通过长波红外线的任何波段中工作。 虽然这种光谱仪对于快速发生的事件特别有用,但也有助于对生命科学中的一些缓慢移动的现象进行调查。

    Device for measurement of the spectral reflectance and process for measurement of the spectral reflectance
    115.
    发明申请
    Device for measurement of the spectral reflectance and process for measurement of the spectral reflectance 失效
    用于测量光谱反射率的装置和用于测量光谱反射率的过程

    公开(公告)号:US20020071118A1

    公开(公告)日:2002-06-13

    申请号:US10011437

    申请日:2001-12-11

    Abstract: A device for measurement of the spectral reflectance of a surface where the reflectance factor of light with a certain wavelength can be measured in a wide wavelength range, including the UV range, and in which a reference reflectance factor can be easily obtained. The device for measurement has a light source part with a xenon lamp; a fiber on the incidence side; a measurement head which emits the light transmitted by the fiber via a convergent lens and a diffuser onto the surface of the measuring object and which receives the light reflected by the surface; a fiber on the exit side; and a spectroradiometer which receives the light which has been transmitted by the fiber on the exit side.

    Abstract translation: 可以在包括UV范围的宽波长范围内测量具有一定波长的光的反射率的表面的光谱反射率的装置,其中可以容易地获得参考反射系数。 用于测量的装置具有带氙灯的光源部分; 发病侧的纤维; 测量头,其通过会聚透镜和漫射器将由光纤传输的光发射到测量对象的表面上,并接收由表面反射的光; 出口侧的纤维; 以及光谱辐射计,其接收由光纤在出射侧发射的光。

    Technique for combined spectral, power, and polarization monitoring
    116.
    发明申请
    Technique for combined spectral, power, and polarization monitoring 有权
    组合光谱,功率和极化监测技术

    公开(公告)号:US20020060785A1

    公开(公告)日:2002-05-23

    申请号:US09828025

    申请日:2001-04-06

    Abstract: An apparatus for use in wave division multiplexing optical telecommunication systems includes a dual photodiode array which converts parallel and perpendicularly polarized light beams at given wavelengths to electrical signals which are digitized and used to rapidly and simultaneously determine all wavelengths and associated components of power and angle of polarization. This information can be displayed for monitoring purposes, or can be used to control signals travelling through optical fiber.

    Abstract translation: 用于波分复用光通信系统的装置包括双光电二极管阵列,其将给定波长的平行和垂直偏振光束转换成电信号,电信号被数字化并用于快速并同时确定功率和角度的所有波长和相关分量 极化。 该信息可以显示用于监视目的,也可以用于控制通过光纤传播的信号。

    Linear spectrometer
    117.
    发明申请
    Linear spectrometer 有权
    线性光谱仪

    公开(公告)号:US20020054289A1

    公开(公告)日:2002-05-09

    申请号:US09952718

    申请日:2001-09-12

    Abstract: A linear spectrometer for spectrally measuring an optical signal. The spectrometer has an input receiving the signal which is then diffracted onto a diffraction grating. The signal is therefore divided into its spectral components, each component being diffracted at an angle null. A correcting element, such as a lens, a group of lenses, a mirror, etc. is provided for focusing the spectral components on an image plane where they are detected. The correcting element is designed so that the resulting distribution of the spectral components on the image plane is linear with respect to the component's wavelength.

    Abstract translation: 用于光谱测量光信号的线性光谱仪。 光谱仪具有接收信号的输入,然后衍射到衍射光栅上。 因此,信号被分成其光谱分量,每个分量以角度θ被衍射。 提供诸如透镜,一组透镜,反射镜等的校正元件,用于将光谱分量聚焦在被检测到的图像平面上。 校正元件被设计成使得所得到的图像平面上的光谱分量的分布相对于分量的波长是线性的。

    Temporally resolved wavelength measurement method and apparatus
    118.
    发明申请
    Temporally resolved wavelength measurement method and apparatus 失效
    时间分辨波长测量方法和装置

    公开(公告)号:US20020044280A1

    公开(公告)日:2002-04-18

    申请号:US09972037

    申请日:2001-10-09

    CPC classification number: G01J3/1804 G01J3/06 G01J2003/2866

    Abstract: The invention provides a method and apparatus for determining the wavelength of a sample source of light, the apparatus having a reference light source of known wavelength, a collimator for collimating light from the sample source and from the reference source, a dispersing means for receiving and spatially dispersing collimated light from the collimator according to wavelength, focusing means for focusing dispersed light from the dispersing means, and a photodetector located in the focal plane of the focusing means and having an aperture for spatially selectively admitting light from the focusing means, and operable to provide a temporally calibratable output signal indicative of the wavelength of the selectively admitted light, wherein the apparatus is operable to scan the focused spatially dispersed beam across the aperture, and the photodetector output includes resolvable features corresponding to light from the reference source and sample source, whereby a time difference between the features is indicative of a wavelength difference between the light from the reference source and the sample source.

    Abstract translation: 本发明提供了一种用于确定样品光源的波长的方法和装置,该装置具有已知波长的参考光源,用于准直来自样品源和参考源的光的准直器,用于接收和 根据波长对来自准直器的准直光进行空间分散,用于聚焦来自分散装置的分散光的聚焦装置,以及位于聚焦装置的焦平面中的光电检测器,并具有用于空间选择性地允许来自聚焦装置的光的孔, 以提供指示所选择的入射光的波长的可临时校准的输出信号,其中该装置可操作以扫过聚焦的空间分散的光束穿过孔,并且光电检测器输出包括对应于来自参考源和样品源的光的可分辨特征 ,由此之间的时间差 这些特征表示来自参考源的光和样品源之间的波长差。

    Digital spectral identifier-controller and related methods
    119.
    发明申请
    Digital spectral identifier-controller and related methods 有权
    数字光谱标识符 - 控制器及相关方法

    公开(公告)号:US20020024665A1

    公开(公告)日:2002-02-28

    申请号:US09849831

    申请日:2001-05-04

    Inventor: Billy R. Masten

    Abstract: A high speed, low cost, wide spectrum light scanning and sensor unit (10) for receiving reflected light from an object and diffracting the light into segments of wavelengths and a linear sensor array (32) having elements positioned to receive the segments and to measure the relative magnitude of such segments to define a spectral distribution of the object together with a digital identifier-controller (36) connected to said sensing device and having a memory for memorizing a spectral distribution of light representing a first standard object, and additional memory for receiving a spectral distributions of other objects and programmable logic circuitry containing a program for determining the similarity between the standard object and the other objects.

    Abstract translation: 一种高速,低成本,宽光谱光扫描和传感器单元(10),用于接收来自物体的反射光并将光衍射成波长段;以及线性传感器阵列(32),其具有被定位成接收段的元件和测量 这些片段的相对大小与连接到所述感测装置的数字标识符 - 控制器(36)一起定义对象的频谱分布,并具有用于存储表示第一标准对象的光的频谱分布的存储器,以及用于 接收包含用于确定标准对象和其他对象之间的相似度的程序的其他对象和可编程逻辑电路的频谱分布。

    In situ spectroscopic method and related apparatus for measuring electrode gap distance
    120.
    发明申请
    In situ spectroscopic method and related apparatus for measuring electrode gap distance 有权
    用于测量电极间隙距离的原位光谱法和相关装置

    公开(公告)号:US20020008872A1

    公开(公告)日:2002-01-24

    申请号:US09876731

    申请日:2001-06-07

    CPC classification number: G01B11/00 G01J3/443

    Abstract: This invention provides a method for accurately measuring a gap distance between two electrodes. According to the method, a plasma space is formed between the electrodes, across which a DC voltage is coupled. The plasma space has a reactive gas that emits a spectrum of spectral lines. The spectrum is monitored to determine at least one line distance between the spectral lines. Finally, the gap distance can be deduced according to the line distance and a specific rule.

    Abstract translation: 本发明提供一种精确测量两个电极之间的间隙距离的方法。 根据该方法,在电极之间形成等离子体空间,通过该电极连接DC电压。 等离子体空间具有发射光谱线谱的反应气体。 监测光谱以确定光谱线之间的至少一行距离。 最后,可以根据行距离和具体规则推导间隙距离。

Patent Agency Ranking