公开(公告)号：WO2007123793A2

公开(公告)日：2007-11-01

申请号：PCT/US2007008058

申请日：2007-04-03

Applicant: STC UNM ,  SMYTH HUGH D ,  DONOVAN MARTIN J

Inventor： SMYTH HUGH D ,  DONOVAN MARTIN J

IPC: A61K9/16

CPC classification number: A61K9/0073 ,  A61K9/0075 ,  A61K9/0078 ,  A61K9/1641 ,  A61K47/60 ,  A61K47/6949 ,  A61K48/00 ,  B82Y5/00 ,  Y10T428/2982

Abstract: Swellable particles for delivery of a drug or other working agent to the pulmonary system are provided. The swellable particles include a dehydrated (dry) aerodynamic particle diameter of 5 µm or less to enable delivery to the respiratory tract, such as for example to the tracheo-bronchial airways of the upper respiratory tract and/or to the alveolic regions of the deep lung, and a hydrated particle diameter that is greater than 6 µm volume mean diameter to retard or prevent their phagocytosis by the macrophages present in airways of the respiratory tract.

Abstract translation: 提供了用于将药物或其它工作剂递送至肺部系统的可溶胀颗粒。 可溶胀颗粒包括5μm或更小的脱水（干燥）空气动力学粒径，以使得能够输送到呼吸道，例如向上呼吸道的气管支气管气道和/或深层的通气区域 肺，以及大于6μm体积平均直径的水合颗粒直径，以阻止或阻止其由呼吸道气道中的巨噬细胞吞噬。

公开(公告)号：WO2005086868A3

公开(公告)日：2007-01-18

申请号：PCT/US2005007786

申请日：2005-03-10

Applicant: STC UNM ,  LESTER LUKE F ,  DAWSON LARRY R ,  PEASE EDWIN A

Inventor： LESTER LUKE F ,  DAWSON LARRY R ,  PEASE EDWIN A

IPC: H01L31/0328 ,  H01L29/201 ,  H01L29/205 ,  H01L29/739 ,  H01L31/0304 ,  H01L31/0352

CPC classification number: H01L29/201 ,  H01L21/02381 ,  H01L21/02392 ,  H01L21/02395 ,  H01L21/02466 ,  H01L21/02507 ,  H01L21/0251 ,  H01L21/02546 ,  H01L21/02549 ,  H01L29/205 ,  H01L31/03046 ,  H01L31/035236

Abstract: A semiconductor device (28) is supported by a substrate (8) with a smaller lattice constant. A metamorphic buffer (10, 12, 14, 16, 18, 20) provides a transition from the smaller lattice constant of the substrate to the larger lattice constant of the semiconductor device. In one application, the semiconductor device has a lattice constant of between approximately 6.1 and 6.35 angstroms, metamorphic buffer layers include Sb (e.g., AlInSb buffer layers), and the substrate has a smaller lattice constant (e.g., Si, InP or GaAs substrates).

Abstract translation: 半导体器件（28）由具有较小晶格常数的衬底（8）支撑。 变质缓冲器（10,12,14,16,18,20）提供从衬底的较小晶格常数到半导体器件的较大晶格常数的转变。 在一个应用中，半导体器件具有约6.1和6.35埃之间的晶格常数，变质缓冲层包括Sb（例如，AlInSb缓冲层），并且衬底具有较小的晶格常数（例如，Si，InP或GaAs衬底） 。

公开(公告)号：WO2005123160A3

公开(公告)日：2006-05-18

申请号：PCT/US2005020831

申请日：2005-06-13

Applicant: STC UNM ,  SIBBITT WILMER L

Inventor： SIBBITT WILMER L

IPC: A61M5/00 ,  A61M5/32

CPC classification number: A61M5/3213 ,  A61M2005/3215

Abstract: A cap or sheath locks onto the needle or other sharp, thus permanently inactivating the needle or other sharp, preventing any further use of the device, and permanently isolating the contaminated sharp. Four components are a needle or sharp to accommodate a locking collar, a sheath with a external, internal, or horizontal track to accommodate a locking collar, a locking collar that moves inferiorly within or outside the sheath, or horizontally that binds to the sheath or needle, permanently locking the needle in the sheath and mechanically preventing the needle from moving from the sheath, and a locking mechanisms for these devices. Handles are advantageously provided for the sheath to permit safe recapping or resheathing so that the needle can be bound in the sheath and inactivated.

Abstract translation: 帽或皮套锁定在针或其他锋利处，从而使针或其他尖锐的永久性钝化，防止该装置的任何进一步使用，并永久隔离受污染的锋利。 四个组件是针或锋利的，以容纳锁定环，具有外部，内部或水平轨道的护套，以容纳锁定环，锁定套环，其在护套内或外部下方移动或水平地移动， 针，将针永久地锁定在护套中并机械地防止针从护套移动，以及用于这些装置的锁定机构。 手柄有利地被提供用于护套以允许安全的重新贴合或再适应，使得针可以绑在护套中并且被钝化。

公开(公告)号：WO2005038997A3

公开(公告)日：2006-01-12

申请号：PCT/US2004034152

申请日：2004-10-14

Applicant: STC UNM ,  KRISHNA SANJAY ,  DAVID JOHN P R ,  HAYAT MAJEED M

Inventor： KRISHNA SANJAY ,  DAVID JOHN P R ,  HAYAT MAJEED M

IPC: H01L29/06 ,  H01L31/0352 ,  H01L31/107 ,  H01S20060101 ,  H01L31/0304

CPC classification number: H01L31/1075 ,  B82Y10/00 ,  B82Y20/00 ,  H01L31/0352

Abstract: A photodetector (100) for use at wavelengths of 2 µm and longer has an intersubband absorption region (110) to provide absorption at wavelengths beyond 2 µm, integrated with an avalanche multiplier region (104) to provide low-noise gain. In one particular design, the intersubband absorption region (110) is a quantum-confined absorption region (e.g., based on quantum wells and/or quantum dots).

Abstract translation: 用于波长为2μm和更长的光检测器（100）具有跨带吸收区域（110），以在超过2μm的波长处提供吸收，与雪崩倍增器区域（104）集成以提供低噪声增益。 在一个特定设计中，子带间吸收区域（110）是量子限制吸收区域（例如，基于量子阱和/或量子点）。

公开(公告)号：WO2004033626A2

公开(公告)日：2004-04-22

申请号：PCT/US0321306

申请日：2003-07-09

Applicant: STC UNM ,  COLE LAURENCE A

Inventor： COLE LAURENCE A

IPC: G01N33/574 ,  G01N33/74 ,  G01N33/76 ,  C12N

CPC classification number: G01N33/57442 ,  G01N33/74 ,  G01N33/76

Abstract: The invention provides methods for detecting the presence or absence of invasive trophoblast cells. In addition, the invention provides methods for distinguishing quiescent trophoblast diseases from invasive trophoblast diseases and methods for monitoring progression of quiescent trophoblast diseases. The invention provides methods for detecting the presence or absence of germ cell tumors.

Abstract translation: 本发明提供了用于检测侵入性滋养细胞存在或不存在的方法。 此外，本发明提供了将静止滋养层疾病与侵入性滋养层疾病区分开来的方法以及监测静息滋养层疾病进展的方法。 本发明提供了用于检测生殖细胞肿瘤的存在或不存在的方法。

公开(公告)号：WO0239083A3

公开(公告)日：2002-07-11

申请号：PCT/US0142983

申请日：2001-11-06

Applicant: STC UNM ,  BURANDA TIONE ,  HUANG JINMAN ,  PEREZ-LUNA VICTOR H ,  LOPEZ GABRIEL P ,  SIMONS PETER ,  SKLAR LARRY A

Inventor： BURANDA TIONE ,  HUANG JINMAN ,  PEREZ-LUNA VICTOR H ,  LOPEZ GABRIEL P ,  SIMONS PETER ,  SKLAR LARRY A

IPC: G01N21/64 ,  G01N33/542 ,  G01N33/543 ,  C07K16/00 ,  C12M1/34 ,  C12M3/00 ,  C12Q1/00 ,  G01N21/00 ,  G01N33/53 ,  G01N33/544 ,  G01N33/545

CPC classification number: G01N33/542 ,  G01N33/54313

Abstract: The invention provides a sensing device comprising: a vessel; a plurality of sensor beads located within the vessel to form interstitial spaces there through; and a plurality of biomolecules bound to at least at portion of the plurality of beads, each of the biomolecules having a fluorescent tag. A sensing device comprised a suspension of a plurality of sensor beads. The invention also provides a method for detecting the binding of two biomolecules comprising the following steps: providing a plurality of first biomolecules, each of the first biomolecules having a first fluorescent tag; and providing a plurality of second biomolecules, each of the second biomolecules having a second fluorescent tag. The binding step have a pre-complexing total fluorescence and detecting any difference between the pre-complexing total fluorescence and the post-complexing total fluorescence.

Abstract translation: 本发明提供一种感测装置，包括：容器; 位于容器内的多个传感器珠，以在其间形成间隙空间; 并且多个生物分子结合到所述多个珠粒的至少一部分上，每个生物分子具有荧光标签。 感测装置包括多个传感器珠的悬架。 本发明还提供了检测两种生物分子的结合的方法，包括以下步骤：提供多个第一生物分子，每个第一生物分子具有第一荧光标记; 并且提供多个第二生物分子，每个第二生物分子具有第二荧光标记。 结合步骤具有预络合的总荧光并检测预络合总荧光和后络合总荧光之间的任何差异。

公开(公告)号：WO2016137968A2

公开(公告)日：2016-09-01

申请号：PCT/US2016019092

申请日：2016-02-23

Applicant: STC UNM ,  MELANCON CHARLES ,  HALL PAMELA ,  GREENBERG JACOB ,  OGASAWARA YASUSHI ,  ROGELJ SNEZNA

Inventor： MELANCON CHARLES ,  HALL PAMELA ,  GREENBERG JACOB ,  OGASAWARA YASUSHI ,  ROGELJ SNEZNA

IPC: A61K31/03

CPC classification number: A61K31/192 ,  A61K31/122

Abstract: In one aspect, this disclosure describes a pharmaceutical composition that generally includes frankiamicin A and a pharmaceutically acceptable carrier. In another aspect, this disclosure describes a method of treating a subject having, or at risk of having, a condition caused by a microbial infection treatable with frankiamicin A. Generally, the method includes administering to the subject an amount of frankiamicin A effective to ameliorate at least one symptom or clinical sign of the condition.

Abstract translation: 在一个方面，本公开描述了一种通常包含法尼基霉素A和药学上可接受的载体的药物组合物。 另一方面，本公开内容描述了治疗患有或可能患有由可用弗农康宁A治疗的微生物感染引起的病症的受试者的方法。通常，所述方法包括向受试者施用有效改善弗米奇霉素A的量 至少一种症状或临床症状。

公开(公告)号：WO2016073055A3

公开(公告)日：2016-07-14

申请号：PCT/US2015045762

申请日：2015-08-18

Applicant: STC UNM ,  ARROWHEAD CT INC ,  SANDIA CORP ,  UNIV INDIANA RES & TECH CORP

Inventor： BUSANI TITO ,  LAVROVA OLGA ,  MARTINEZ JULIO ,  SHELNUTT JOHN A ,  ZHANG SHIXIONG

IPC: H02S10/30 ,  H02S40/40 ,  H02S40/44

CPC classification number: H02S10/30 ,  H01G9/0029 ,  H01G9/2013 ,  H01G9/2022 ,  H01G9/204 ,  H01G9/2059 ,  H01L31/0547 ,  H01L35/00 ,  H01L51/0036 ,  H01L51/0048 ,  H01L51/0049 ,  H01L51/0056 ,  H01L51/006 ,  H01L51/0092 ,  H01L51/4233 ,  H02S40/38 ,  Y02B10/10 ,  Y02B10/70 ,  Y02E10/52 ,  Y02E10/549 ,  Y02P70/521

Abstract: The present invention is a photovoltaic-thermoelectric solar cell and a method of manufacturing a photovoltaic-thermoelectric solar cell. The solar cell includes a substantially transparent electrode, an organometallic photovoltaic material disposed on the transparent electrode, and a cathode disposed on the organometallic photovoltaic material. The organometallic photovoltaic material may be a porphyrin nanomaterial.

Abstract translation: 本发明是一种光电热电太阳能电池及其制造方法。 太阳能电池包括基本上透明的电极，设置在透明电极上的有机金属光伏材料和设置在有机金属光伏材料上的阴极。 有机金属光伏材料可以是卟啉纳米材料。

公开(公告)号：WO2015126930A3

公开(公告)日：2015-11-05

申请号：PCT/US2015016359

申请日：2015-02-18

Applicant: STC UNM

Inventor： TIMMINS GRAHAM ,  CHOI SEONG WON

IPC: A61K31/425 ,  A61K31/185 ,  A61K31/4965 ,  A61K31/606 ,  A61P31/06

CPC classification number: A61K31/16 ,  A61K9/0075 ,  A61K31/4965 ,  A61K45/06 ,  A61K2300/00

Abstract: In one embodiment, the invention provides a method of treating a subject who suffers from, or who is suspected of suffering from, a Mycobacterium infection, the method comprising administering to the subject a therapeutically effective amount of a urease inhibitor, optionally in combination with one or more anti-mycobacterial agents.

Abstract translation: 在一个实施方案中，本发明提供了治疗患有或怀疑患有分枝杆菌感染的受试者的方法，所述方法包括向所述受试者施用治疗有效量的脲酶抑制剂，任选地与一种 或更多的抗分枝杆菌剂。

公开(公告)号：WO2015054044A3

公开(公告)日：2015-08-06

申请号：PCT/US2014058949

申请日：2014-10-03

Applicant: STC UNM

Inventor： LESEMAN ZAYD ,  ABBAS KHAWAR ,  ELAHI MIRZA ,  KHEYRADDINI MOUSAVI ARASH ,  LIMA EDIDSON ,  MOYA STEPHEN

IPC: C23F4/00 ,  C23F1/00

CPC classification number: B23K10/006 ,  B23K10/003 ,  G01F17/00 ,  G01F22/02 ,  G04F13/06

Abstract: Provided is a method for determining a volume, at room temperature, of a first chamber having an unknown volume that is in fluid communication through a controllable valve with a second chamber having an unknown volume. The method can include measuring, by a pressure sensor coupled to one of the first chamber and the second chamber, a first equilibrium pressure of a gas that was introduced into the second chamber in both the first chamber and the second chamber after equilibrium is reached; measuring, by the pressure sensor, a second equilibrium pressure of the gas that was introduced into the second chamber in both the first chamber and the second chamber after equilibrium is reached, wherein the first chamber comprises an object with a known volume therein; and determining the volume of the first chamber based on the first equilibrium pressure and the second equilibrium pressure.

Abstract translation: 提供一种用于确定在室温下具有未知体积的第一腔室的体积的方法，所述第一腔室通过可控阀与具有未知体积的第二腔室流体连通。 该方法可以包括：通过与第一腔室和第二腔室中的一个连接的压力传感器测量在达到平衡之后在第一腔室和第二腔室中引入到第二腔室中的气体的第一平衡压力; 在达到平衡之后，通过压力传感器测量在第一腔室和第二腔室两者中引入到第二腔室中的气体的第二平衡压力，其中第一腔室包括其中具有已知体积的物体; 以及基于第一平衡压力和第二平衡压力确定第一腔室的容积。